ENSG00000151779

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000281513 ENSG00000151779 HEK293_OSMI2_6hA HEK293_TMG_6hB NBAS protein_coding protein_coding 9.045853 5.6467 8.893101 2.067364 0.1972955 0.6543473 4.1687109 1.5118520 6.9424164 0.5150174 0.18328097 2.1916864 0.4597958 0.2706667 0.7817333 0.51106667 2.376557e-09 2.376557e-09 FALSE TRUE
ENST00000417461 ENSG00000151779 HEK293_OSMI2_6hA HEK293_TMG_6hB NBAS protein_coding protein_coding 9.045853 5.6467 8.893101 2.067364 0.1972955 0.6543473 0.9781249 0.6887068 0.1927979 0.4577819 0.10692821 -1.7846448 0.1041833 0.1093667 0.0212000 -0.08816667 7.912318e-01 2.376557e-09 TRUE TRUE
ENST00000433283 ENSG00000151779 HEK293_OSMI2_6hA HEK293_TMG_6hB NBAS protein_coding protein_coding 9.045853 5.6467 8.893101 2.067364 0.1972955 0.6543473 1.4180093 0.9407325 0.5351619 0.5593138 0.02642763 -0.8023547 0.1536708 0.1636667 0.0603000 -0.10336667 9.291239e-01 2.376557e-09 FALSE TRUE
ENST00000442506 ENSG00000151779 HEK293_OSMI2_6hA HEK293_TMG_6hB NBAS protein_coding protein_coding 9.045853 5.6467 8.893101 2.067364 0.1972955 0.6543473 1.4447500 1.8076625 0.0000000 0.6577045 0.00000000 -7.5059406 0.1651917 0.3250000 0.0000000 -0.32500000 3.026690e-08 2.376557e-09 FALSE TRUE
MSTRG.17988.5 ENSG00000151779 HEK293_OSMI2_6hA HEK293_TMG_6hB NBAS protein_coding   9.045853 5.6467 8.893101 2.067364 0.1972955 0.6543473 0.9419858 0.6196186 1.1841150 0.1739931 0.24501682 0.9233916 0.1065625 0.1158333 0.1323333 0.01650000 9.527202e-01 2.376557e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000151779 E001 0.3088520 0.0269272384 5.705288e-01   2 15166914 15166915 2 - 0.086 0.169 1.112
ENSG00000151779 E002 0.3088520 0.0269272384 5.705288e-01   2 15166916 15166916 1 - 0.086 0.169 1.112
ENSG00000151779 E003 69.5693867 0.0009394607 1.109480e-15 1.852657e-13 2 15166917 15167323 407 - 1.668 2.020 1.185
ENSG00000151779 E004 0.0000000       2 15177949 15178157 209 -      
ENSG00000151779 E005 47.1608619 0.0009654398 1.408518e-07 5.051716e-06 2 15178988 15179116 129 - 1.535 1.814 0.948
ENSG00000151779 E006 2.1010928 0.0098558186 6.506190e-03 4.223950e-02 2 15179117 15180378 1262 - 0.273 0.722 2.286
ENSG00000151779 E007 66.2198653 0.0091636617 7.253760e-05 1.143435e-03 2 15186742 15186880 139 - 1.684 1.951 0.900
ENSG00000151779 E008 67.5705777 0.0059975131 1.985238e-03 1.696809e-02 2 15190264 15190403 140 - 1.726 1.917 0.647
ENSG00000151779 E009 63.1473929 0.0013683963 5.318483e-07 1.634457e-05 2 15218773 15218968 196 - 1.678 1.921 0.819
ENSG00000151779 E010 39.9702908 0.0023578097 2.328536e-04 3.033438e-03 2 15232422 15232511 90 - 1.495 1.718 0.761
ENSG00000151779 E011 67.6727449 0.0006244876 7.018577e-04 7.456931e-03 2 15234545 15234747 203 - 1.743 1.897 0.520
ENSG00000151779 E012 84.2287339 0.0005249314 8.844629e-05 1.348556e-03 2 15238468 15238686 219 - 1.836 1.995 0.536
ENSG00000151779 E013 99.3706962 0.0005301509 2.386693e-02 1.086847e-01 2 15275484 15275818 335 - 1.938 2.026 0.294
ENSG00000151779 E014 73.2540627 0.0005832028 2.139450e-04 2.829656e-03 2 15276851 15277101 251 - 1.776 1.937 0.543
ENSG00000151779 E015 43.4290905 0.0009327690 5.728599e-03 3.838421e-02 2 15287073 15287183 111 - 1.560 1.715 0.527
ENSG00000151779 E016 63.9369465 0.0039444478 4.618897e-01 6.744177e-01 2 15292537 15292766 230 - 1.767 1.809 0.142
ENSG00000151779 E017 46.2189588 0.0047701617 1.644697e-01 3.833427e-01 2 15308216 15308353 138 - 1.604 1.701 0.330
ENSG00000151779 E018 31.7623380 0.0011468453 4.562789e-02 1.690858e-01 2 15309171 15309247 77 - 1.433 1.564 0.452
ENSG00000151779 E019 36.8300747 0.0011168931 4.357847e-02 1.640719e-01 2 15327750 15327870 121 - 1.498 1.622 0.425
ENSG00000151779 E020 38.6452294 0.0013314073 2.341683e-01 4.699276e-01 2 15328199 15328312 114 - 1.583 1.510 -0.248
ENSG00000151779 E021 45.2151657 0.0070153283 3.867495e-01 6.179285e-01 2 15330598 15330765 168 - 1.645 1.584 -0.207
ENSG00000151779 E022 31.4105672 0.0048729233 3.278867e-01 5.669452e-01 2 15351992 15352081 90 - 1.444 1.519 0.257
ENSG00000151779 E023 40.6877875 0.0009970915 5.801918e-01 7.572817e-01 2 15353553 15353710 158 - 1.595 1.564 -0.105
ENSG00000151779 E024 35.5914425 0.0052646606 3.296576e-01 5.685923e-01 2 15356303 15356416 114 - 1.552 1.484 -0.234
ENSG00000151779 E025 35.0061184 0.0051523875 7.103065e-01 8.419749e-01 2 15366580 15366693 114 - 1.536 1.509 -0.092
ENSG00000151779 E026 38.8681735 0.0033649598 2.738118e-01 5.137389e-01 2 15374608 15374720 113 - 1.593 1.522 -0.242
ENSG00000151779 E027 43.7641718 0.0015205372 9.418422e-01 9.731821e-01 2 15379602 15379831 230 - 1.621 1.626 0.020
ENSG00000151779 E028 27.8986604 0.0013450674 5.126506e-01 7.099424e-01 2 15383215 15383317 103 - 1.415 1.463 0.166
ENSG00000151779 E029 0.1779838 0.0355938437 1.000000e+00   2 15393639 15393727 89 - 0.086 0.000 -7.924
ENSG00000151779 E030 40.7239033 0.0009511526 1.096483e-01 2.984630e-01 2 15394227 15394349 123 - 1.616 1.523 -0.320
ENSG00000151779 E031 36.1976959 0.0011583157 2.920207e-01 5.327013e-01 2 15396413 15396475 63 - 1.555 1.491 -0.219
ENSG00000151779 E032 47.2086588 0.0010311211 5.421032e-01 7.305770e-01 2 15402168 15402301 134 - 1.654 1.622 -0.107
ENSG00000151779 E033 40.8034038 0.0011263609 6.435177e-01 7.992188e-01 2 15415546 15415719 174 - 1.590 1.564 -0.088
ENSG00000151779 E034 42.0719323 0.0011198768 3.853474e-01 6.167324e-01 2 15417527 15417712 186 - 1.614 1.564 -0.170
ENSG00000151779 E035 44.1518120 0.0078163125 9.540653e-01 9.789627e-01 2 15424315 15424468 154 - 1.616 1.619 0.010
ENSG00000151779 E036 36.0706458 0.0167094732 2.994355e-01 5.398486e-01 2 15427711 15427794 84 - 1.553 1.478 -0.257
ENSG00000151779 E037 39.6565922 0.0009823159 3.239254e-03 2.483521e-02 2 15461201 15461337 137 - 1.625 1.441 -0.631
ENSG00000151779 E038 26.0518397 0.0043686005 1.068867e-02 6.105353e-02 2 15461687 15461791 105 - 1.457 1.246 -0.733
ENSG00000151779 E039 29.2798377 0.0055780464 8.036232e-02 2.455711e-01 2 15467329 15467407 79 - 1.490 1.350 -0.483
ENSG00000151779 E040 36.7208058 0.0012704227 7.822918e-03 4.849467e-02 2 15467664 15467804 141 - 1.590 1.418 -0.591
ENSG00000151779 E041 29.5810153 0.0012456085 4.331341e-03 3.099711e-02 2 15468382 15468533 152 - 1.507 1.301 -0.712
ENSG00000151779 E042 26.7389986 0.0013241138 5.699407e-05 9.329964e-04 2 15473222 15473347 126 - 1.489 1.170 -1.113
ENSG00000151779 E043 53.7220027 0.0012719485 3.676111e-06 8.833851e-05 2 15474067 15474324 258 - 1.778 1.516 -0.889
ENSG00000151779 E044 38.2783920 0.0036799799 4.105586e-05 7.036970e-04 2 15475687 15475880 194 - 1.640 1.350 -0.997
ENSG00000151779 E045 13.2260431 0.0026793247 2.822889e-03 2.233164e-02 2 15478226 15478244 19 - 1.207 0.884 -1.184
ENSG00000151779 E046 20.4015109 0.0020565299 8.139581e-05 1.259799e-03 2 15478245 15478289 45 - 1.385 1.021 -1.290
ENSG00000151779 E047 0.0000000       2 15483262 15483368 107 -      
ENSG00000151779 E048 28.2192481 0.0022939633 2.812970e-04 3.541193e-03 2 15488894 15489022 129 - 1.507 1.222 -0.988
ENSG00000151779 E049 28.2952769 0.0211311668 9.820757e-03 5.735264e-02 2 15504145 15504213 69 - 1.504 1.226 -0.963
ENSG00000151779 E050 30.6015783 0.0011336365 2.591977e-04 3.315087e-03 2 15511212 15511350 139 - 1.535 1.269 -0.922
ENSG00000151779 E051 27.5565069 0.0017017982 8.642697e-05 1.322636e-03 2 15534543 15534641 99 - 1.504 1.197 -1.069
ENSG00000151779 E052 28.3004148 0.0013146750 6.921728e-04 7.376646e-03 2 15536418 15536551 134 - 1.501 1.246 -0.884
ENSG00000151779 E053 27.2884206 0.0014303977 1.380720e-03 1.276348e-02 2 15539223 15539356 134 - 1.479 1.235 -0.851
ENSG00000151779 E054 16.3620431 0.0019631794 8.784553e-04 8.917563e-03 2 15551493 15551536 44 - 1.288 0.958 -1.188
ENSG00000151779 E055 19.6645885 0.0017090845 1.624925e-04 2.247513e-03 2 15553426 15553473 48 - 1.368 1.021 -1.234
ENSG00000151779 E056 24.1093034 0.0013907548 3.191146e-06 7.826834e-05 2 15554061 15554138 78 - 1.460 1.059 -1.413
ENSG00000151779 E057 19.0288883 0.0017983164 8.674393e-04 8.828957e-03 2 15556783 15556819 37 - 1.347 1.041 -1.091
ENSG00000151779 E058 22.8483691 0.0016191281 1.882329e-03 1.628108e-02 2 15558580 15558634 55 - 1.415 1.156 -0.908
ENSG00000151779 E059 23.3670358 0.0058222484 2.405969e-02 1.092688e-01 2 15561188 15561334 147 - 1.410 1.211 -0.699