ENSG00000151338

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396294 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding protein_coding 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.18920730 0.00000000 0.3719862 0.00000000 0.04888427 5.255448 0.05578750 0.00000000 0.07943333 0.079433333 0.03834132 0.03834132 FALSE TRUE
ENST00000554829 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding retained_intron 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.03921398 0.05668432 0.0000000 0.05668432 0.00000000 -2.737347 0.03189583 0.05130000 0.00000000 -0.051300000 0.54331745 0.03834132   FALSE
ENST00000554930 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding processed_transcript 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.62596781 0.17338490 0.6383094 0.08802720 0.32606742 1.821808 0.17734583 0.18566667 0.14293333 -0.042733333 0.97634190 0.03834132 FALSE TRUE
ENST00000556615 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding protein_coding 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.31328439 0.09192053 0.5418295 0.09192053 0.31126164 2.436778 0.07761250 0.11716667 0.10990000 -0.007266667 0.89889079 0.03834132 FALSE FALSE
ENST00000556753 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding protein_coding 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.25155738 0.10736342 0.0000000 0.10736342 0.00000000 -3.552911 0.05589167 0.09713333 0.00000000 -0.097133333 0.60674421 0.03834132 FALSE FALSE
ENST00000694961 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding protein_coding 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.72769766 0.14963888 1.6401441 0.14963888 0.14446130 3.369708 0.17944583 0.18030000 0.34923333 0.168933333 0.52052865 0.03834132 FALSE TRUE
ENST00000694964 ENSG00000151338 HEK293_OSMI2_6hA HEK293_TMG_6hB MIPOL1 protein_coding protein_coding 3.18452 0.9065604 4.692885 0.1002168 0.2203691 2.359244 0.22116446 0.03992912 0.4000130 0.02019961 0.04433123 3.037716 0.08965000 0.04940000 0.08490000 0.035500000 0.63422044 0.03834132 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000151338 E001 0.0000000       14 37197894 37197912 19 +      
ENSG00000151338 E002 0.6600180 0.019387492 0.5947526026   14 37197913 37197929 17 + 0.197 0.000 -11.239
ENSG00000151338 E003 0.6600180 0.019387492 0.5947526026   14 37197930 37197931 2 + 0.197 0.000 -13.464
ENSG00000151338 E004 0.6600180 0.019387492 0.5947526026   14 37197932 37197932 1 + 0.197 0.000 -13.464
ENSG00000151338 E005 0.9335208 0.015914464 1.0000000000   14 37197933 37197936 4 + 0.235 0.236 0.009
ENSG00000151338 E006 1.5276421 0.018117643 0.7813755138 0.88547808 14 37197937 37197949 13 + 0.332 0.388 0.330
ENSG00000151338 E007 2.3730184 0.009422835 0.1168946319 0.31066349 14 37197950 37197955 6 + 0.387 0.664 1.331
ENSG00000151338 E008 5.9453100 0.004780499 0.4734911572 0.68244436 14 37197956 37198009 54 + 0.725 0.831 0.424
ENSG00000151338 E009 6.8208739 0.004669191 0.7230062495 0.84996963 14 37198010 37198027 18 + 0.781 0.832 0.200
ENSG00000151338 E010 6.7442062 0.004778424 0.9609921914 0.98245518 14 37198028 37198036 9 + 0.791 0.782 -0.033
ENSG00000151338 E011 8.5601383 0.011033993 0.4318774538 0.65264889 14 37198037 37198067 31 + 0.898 0.781 -0.452
ENSG00000151338 E012 9.4308285 0.003507965 0.7146322517 0.84469697 14 37198068 37198086 19 + 0.905 0.952 0.175
ENSG00000151338 E013 9.6054157 0.003162180 0.5211521790 0.71566661 14 37198087 37198092 6 + 0.905 0.986 0.301
ENSG00000151338 E014 9.5534984 0.003324612 0.5208556278 0.71549317 14 37198093 37198104 12 + 0.905 0.986 0.301
ENSG00000151338 E015 0.3032425 0.027442404 0.0123460803   14 37198105 37198278 174 + 0.000 0.389 15.346
ENSG00000151338 E016 0.1779838 0.037410704 1.0000000000   14 37207142 37207244 103 + 0.058 0.000 -11.732
ENSG00000151338 E017 0.7507353 0.048879086 0.4490840734   14 37212230 37212356 127 + 0.234 0.000 -13.701
ENSG00000151338 E018 3.0537929 0.008580063 0.9428769220 0.97373640 14 37219553 37219691 139 + 0.518 0.502 -0.080
ENSG00000151338 E019 0.0000000       14 37220799 37220918 120 +      
ENSG00000151338 E020 2.6199196 0.009506263 0.6617156302 0.81091179 14 37227726 37227838 113 + 0.479 0.389 -0.476
ENSG00000151338 E021 0.2027342 0.081474636 0.0757910204   14 37234378 37234459 82 + 0.000 0.238 14.255
ENSG00000151338 E022 0.1779838 0.037410704 1.0000000000   14 37240433 37240461 29 + 0.058 0.000 -11.732
ENSG00000151338 E023 1.0457254 0.323754031 0.9194421168   14 37240462 37240569 108 + 0.241 0.238 -0.025
ENSG00000151338 E024 20.1940383 0.001716354 0.7653858782 0.87588866 14 37247103 37247240 138 + 1.203 1.229 0.091
ENSG00000151338 E025 0.0000000       14 37247799 37247828 30 +      
ENSG00000151338 E026 18.9219730 0.002193038 0.2930090452 0.53370167 14 37247829 37247907 79 + 1.166 1.264 0.347
ENSG00000151338 E027 0.6544085 0.019080085 0.6475189022   14 37265207 37265281 75 + 0.156 0.237 0.749
ENSG00000151338 E028 12.2649879 0.005259800 0.9176495317 0.96104485 14 37266938 37266950 13 + 1.009 1.017 0.033
ENSG00000151338 E029 20.7639407 0.002342379 0.5410912023 0.72982226 14 37266951 37267066 116 + 1.210 1.264 0.190
ENSG00000151338 E030 21.5103702 0.001901561 0.8413260713 0.92018934 14 37267067 37267169 103 + 1.233 1.210 -0.082
ENSG00000151338 E031 23.9164547 0.004692854 0.6782526275 0.82160819 14 37268658 37268793 136 + 1.266 1.298 0.113
ENSG00000151338 E032 21.0480117 0.008519391 0.9022773045 0.95301364 14 37270420 37270525 106 + 1.226 1.209 -0.062
ENSG00000151338 E033 2.6247418 0.026031704 0.0313919631 0.13146599 14 37276330 37278874 2545 + 0.536 0.000 -14.966
ENSG00000151338 E034 16.1118966 0.002540723 0.5414507687 0.73010438 14 37285318 37285372 55 + 1.107 1.169 0.221
ENSG00000151338 E035 22.6528573 0.001670973 0.7186023750 0.84735494 14 37285373 37285447 75 + 1.251 1.281 0.105
ENSG00000151338 E036 3.4253309 0.083197340 0.0523165907 0.18506031 14 37288580 37290205 1626 + 0.475 0.831 1.540
ENSG00000151338 E037 0.9889386 0.217062971 0.0771016047   14 37290206 37290368 163 + 0.155 0.576 2.687
ENSG00000151338 E038 0.3751086 0.036973391 0.0121978059   14 37302501 37306476 3976 + 0.000 0.390 15.315
ENSG00000151338 E039 18.1078371 0.001893107 0.6467416176 0.80129865 14 37308056 37308089 34 + 1.174 1.124 -0.181
ENSG00000151338 E040 25.2572719 0.001838526 0.9392270510 0.97189644 14 37308349 37308457 109 + 1.306 1.297 -0.033
ENSG00000151338 E041 19.8935089 0.002176062 0.7664354273 0.87646959 14 37308458 37308519 62 + 1.203 1.228 0.092
ENSG00000151338 E042 0.0000000       14 37350091 37350214 124 +      
ENSG00000151338 E043 22.9910575 0.006729624 0.5251261769 0.71851993 14 37369517 37369624 108 + 1.277 1.209 -0.239
ENSG00000151338 E044 0.1779838 0.037410704 1.0000000000   14 37369625 37369939 315 + 0.058 0.000 -11.732
ENSG00000151338 E045 0.0000000       14 37385494 37385779 286 +      
ENSG00000151338 E046 0.3206185 0.027442404 1.0000000000   14 37396976 37397014 39 + 0.110 0.000 -12.630
ENSG00000151338 E047 0.0000000       14 37399745 37399748 4 +      
ENSG00000151338 E048 0.0000000       14 37399749 37399749 1 +      
ENSG00000151338 E049 0.0000000       14 37399750 37399754 5 +      
ENSG00000151338 E050 0.0000000       14 37399755 37399799 45 +      
ENSG00000151338 E051 0.0000000       14 37399800 37400059 260 +      
ENSG00000151338 E052 0.0000000       14 37400060 37402113 2054 +      
ENSG00000151338 E053 0.0000000       14 37402114 37402226 113 +      
ENSG00000151338 E054 0.2027342 0.081474636 0.0757910204   14 37402227 37402528 302 + 0.000 0.238 14.255
ENSG00000151338 E055 0.2027342 0.081474636 0.0757910204   14 37406567 37406670 104 + 0.000 0.238 14.255
ENSG00000151338 E056 0.0000000       14 37417326 37417486 161 +      
ENSG00000151338 E057 0.0000000       14 37419228 37419459 232 +      
ENSG00000151338 E058 20.4137389 0.001707437 0.2250039527 0.45943616 14 37422855 37422949 95 + 1.229 1.100 -0.462
ENSG00000151338 E059 1.2389762 0.014535190 0.1601403035   14 37423525 37424588 1064 + 0.235 0.501 1.593
ENSG00000151338 E060 0.7063259 0.575781865 0.5823556882   14 37430597 37431559 963 + 0.161 0.239 0.706
ENSG00000151338 E061 0.0000000       14 37437608 37437724 117 +      
ENSG00000151338 E062 1.5817723 0.013165317 0.7793892391 0.88437665 14 37476892 37477062 171 + 0.333 0.388 0.329
ENSG00000151338 E063 31.3435237 0.002369376 0.1226116398 0.31991452 14 37499908 37500138 231 + 1.415 1.280 -0.469
ENSG00000151338 E064 2.5591118 0.052735561 0.0046646553 0.03281697 14 37501517 37507790 6274 + 0.331 0.833 2.344
ENSG00000151338 E065 0.0000000       14 37510588 37510668 81 +      
ENSG00000151338 E066 0.0000000       14 37515884 37516689 806 +      
ENSG00000151338 E067 0.3206185 0.027442404 1.0000000000   14 37518372 37519235 864 + 0.110 0.000 -12.630
ENSG00000151338 E068 14.9733460 0.020834977 0.7257690437 0.85162873 14 37520958 37523472 2515 + 1.098 1.045 -0.194
ENSG00000151338 E069 0.1779838 0.037410704 1.0000000000   14 37523473 37523569 97 + 0.058 0.000 -11.732
ENSG00000151338 E070 0.1779838 0.037410704 1.0000000000   14 37523570 37524557 988 + 0.058 0.000 -11.732
ENSG00000151338 E071 0.4466850 0.026201543 1.0000000000   14 37535926 37536047 122 + 0.155 0.000 -13.123
ENSG00000151338 E072 0.6597577 0.589655407 0.0957636577   14 37536048 37538619 2572 + 0.057 0.510 3.984
ENSG00000151338 E073 0.1723744 0.035221713 0.0739021647   14 37538620 37539077 458 + 0.000 0.237 14.403
ENSG00000151338 E074 0.6412370 0.034252431 0.5985394262   14 37545665 37546904 1240 + 0.197 0.000 -13.457
ENSG00000151338 E075 74.7917210 0.005883860 0.0265524906 0.11693438 14 37546905 37553986 7082 + 1.776 1.626 -0.510
ENSG00000151338 E076 0.3393995 0.027442404 1.0000000000   14 37564047 37564218 172 + 0.110 0.000 -12.630
ENSG00000151338 E077 0.7673035 0.018434007 0.4358202365   14 37564219 37564362 144 + 0.235 0.000 -13.715
ENSG00000151338 E078 0.2852693 0.363136079 1.0000000000   14 37564363 37564366 4 + 0.108 0.000 -12.307
ENSG00000151338 E079 1.4461025 0.011999996 0.1558732802 0.37073623 14 37564367 37569053 4687 + 0.361 0.000 -14.345
ENSG00000151338 E080 0.9402750 0.029138217 0.0004363953   14 37578704 37579125 422 + 0.058 0.664 4.652