ENSG00000151332

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318473 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding protein_coding 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 1.5505888 0.7444278 3.0689514 0.20797432 0.68130732 2.028984 0.09447917 0.14390000 0.082000000 -0.06190000 4.254607e-01 3.140941e-16 FALSE TRUE
ENST00000359527 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding protein_coding 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 0.9310581 0.1049771 2.7039207 0.05480109 0.56475016 4.560960 0.03827917 0.02073333 0.071733333 0.05100000 2.660758e-01 3.140941e-16 FALSE TRUE
ENST00000416007 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding protein_coding 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 9.9813523 3.3021727 18.0668817 0.48238458 0.65904103 2.448296 0.61093750 0.65670000 0.485200000 -0.17150000 3.441486e-01 3.140941e-16 FALSE TRUE
ENST00000604154 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding processed_transcript 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 0.2085590 0.4087675 0.1952108 0.25503732 0.09795503 -1.029043 0.02022500 0.06953333 0.005233333 -0.06430000 5.534961e-01 3.140941e-16   FALSE
ENST00000604336 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding protein_coding 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 1.2516206 0.3105387 2.2050430 0.22474951 0.64230487 2.788764 0.05500000 0.07676667 0.057900000 -0.01886667 9.387746e-01 3.140941e-16 FALSE TRUE
ENST00000605579 ENSG00000151332 HEK293_OSMI2_6hA HEK293_TMG_6hB MBIP protein_coding protein_coding 19.08615 5.050981 37.39212 0.7431969 1.548687 2.885631 3.5961189 0.0000000 7.1234117 0.00000000 0.52354725 9.478448 0.11235417 0.00000000 0.190300000 0.19030000 3.140941e-16 3.140941e-16 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000151332 E001 0.4279040 0.5845781846 1.000000e+00   14 36298564 36298567 4 - 0.145 0.001 -8.084
ENSG00000151332 E002 0.5893196 0.0888690915 6.700189e-01   14 36298568 36298589 22 - 0.189 0.000 -10.782
ENSG00000151332 E003 162.1579776 0.0003774560 7.118196e-02 0.2271090762 14 36298590 36299116 527 - 2.064 2.129 0.218
ENSG00000151332 E004 59.0298255 0.0007137334 5.688557e-01 0.7494284676 14 36299117 36299117 1 - 1.639 1.675 0.122
ENSG00000151332 E005 99.3803723 0.0006017164 6.609174e-01 0.8105015782 14 36299118 36299187 70 - 1.863 1.886 0.075
ENSG00000151332 E006 54.4152889 0.0006791336 8.384407e-01 0.9185614784 14 36299188 36299190 3 - 1.610 1.599 -0.040
ENSG00000151332 E007 74.9251622 0.0005391651 3.106743e-01 0.5511642055 14 36300785 36300823 39 - 1.735 1.790 0.186
ENSG00000151332 E008 1.3674438 0.0572254897 1.065489e-02   14 36300824 36301020 197 - 0.190 0.677 2.775
ENSG00000151332 E009 4.2925969 0.0066178639 5.267853e-01 0.7196818067 14 36305089 36305304 216 - 0.633 0.515 -0.533
ENSG00000151332 E010 0.6434498 0.0195965162 6.337966e-01   14 36308017 36308091 75 - 0.190 0.000 -10.733
ENSG00000151332 E011 74.6948312 0.0006733823 9.883129e-01 0.9959341120 14 36308092 36308156 65 - 1.740 1.740 0.000
ENSG00000151332 E012 75.7111449 0.0005510671 7.611985e-01 0.8733035106 14 36308157 36308189 33 - 1.749 1.733 -0.053
ENSG00000151332 E013 69.3114129 0.0006914396 3.951024e-01 0.6244741591 14 36311573 36311576 4 - 1.716 1.668 -0.165
ENSG00000151332 E014 144.5588854 0.0003523075 5.900681e-01 0.7638046750 14 36311577 36311725 149 - 2.024 2.045 0.073
ENSG00000151332 E015 97.8323845 0.0064140479 1.313601e-01 0.3339497197 14 36311959 36312024 66 - 1.846 1.930 0.282
ENSG00000151332 E016 22.1253272 0.0016738226 3.657659e-05 0.0006387851 14 36313290 36314511 1222 - 1.284 0.744 -2.002
ENSG00000151332 E017 118.0915086 0.0024613050 8.083979e-01 0.9012280733 14 36314512 36314608 97 - 1.938 1.949 0.038
ENSG00000151332 E018 84.6514462 0.0023423427 6.408985e-01 0.7974579463 14 36314691 36314700 10 - 1.799 1.774 -0.087
ENSG00000151332 E019 188.1032913 0.0003287423 8.976019e-02 0.2633384293 14 36314701 36314915 215 - 2.148 2.090 -0.193
ENSG00000151332 E020 2.2513279 0.0096372090 9.175437e-01 0.9609977449 14 36314916 36314936 21 - 0.422 0.401 -0.114
ENSG00000151332 E021 120.3125905 0.0003660084 8.904349e-01 0.9469130402 14 36316693 36316812 120 - 1.947 1.942 -0.016
ENSG00000151332 E022 4.6261656 0.0070044644 3.874869e-02 0.1514829530 14 36319585 36319870 286 - 0.685 0.245 -2.340
ENSG00000151332 E023 82.1017893 0.0004650430 3.712451e-01 0.6049316689 14 36320460 36320637 178 - 1.792 1.745 -0.156