ENSG00000150401

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460318 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding processed_transcript 5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 0.04708465 0.3117750 0.00000000 0.14180918 0.00000000 -5.0079804 0.01216667 0.08906667 0.00000000 -0.089066667 0.001041744 0.001041744 FALSE TRUE
ENST00000465710 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding protein_coding 5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 0.43306122 0.2756238 0.42192666 0.22934817 0.18847343 0.5966702 0.06934583 0.06093333 0.05016667 -0.010766667 0.984685956 0.001041744   FALSE
ENST00000465938 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding protein_coding 5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 1.40811501 0.2559456 2.74820452 0.25594562 0.36622266 3.3745263 0.19894583 0.05283333 0.33260000 0.279766667 0.153500752 0.001041744 FALSE FALSE
ENST00000478244 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding protein_coding 5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 0.76526470 0.5213739 0.85153350 0.39006034 0.09532442 0.6971795 0.14454583 0.14340000 0.10350000 -0.039900000 0.922864672 0.001041744 FALSE TRUE
MSTRG.9103.1 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding   5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 2.31040836 1.6083810 3.47536954 0.45925264 0.06228024 1.1067604 0.41969167 0.43390000 0.42566667 -0.008233333 1.000000000 0.001041744 TRUE TRUE
MSTRG.9103.5 ENSG00000150401 HEK293_OSMI2_6hA HEK293_TMG_6hB DCUN1D2 protein_coding   5.810123 3.765864 8.198496 0.5547932 0.329475 1.120311 0.27727854 0.4477126 0.08675097 0.08925071 0.08675097 -2.2420942 0.05346667 0.12833333 0.01040000 -0.117933333 0.094761216 0.001041744 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000150401 E001 0.5171231 0.4885849049 0.1241390358   13 113455815 113455818 4 - 0.000 0.363 10.716
ENSG00000150401 E002 152.9123839 0.0004207767 0.0001107497 0.001627539 13 113455819 113457796 1978 - 2.131 2.232 0.336
ENSG00000150401 E003 8.6624727 0.0825108573 0.3473589913 0.584842421 13 113457797 113457798 2 - 0.916 1.073 0.579
ENSG00000150401 E004 51.2766691 0.0011407228 0.2471671712 0.484863931 13 113457799 113458108 310 - 1.722 1.667 -0.186
ENSG00000150401 E005 31.6982048 0.0013228901 0.1790757518 0.402727761 13 113459312 113459408 97 - 1.526 1.444 -0.284
ENSG00000150401 E006 0.3336024 0.0274424043 0.0893540996   13 113459409 113459543 135 - 0.000 0.267 13.050
ENSG00000150401 E007 16.3550829 0.0024715101 0.5328765376 0.724104800 13 113461054 113461054 1 - 1.241 1.189 -0.184
ENSG00000150401 E008 28.9138918 0.0013776130 0.5001694235 0.700862023 13 113461055 113461136 82 - 1.472 1.430 -0.145
ENSG00000150401 E009 22.3751429 0.0023956441 0.2104854150 0.442403361 13 113462740 113462891 152 - 1.385 1.294 -0.318
ENSG00000150401 E010 0.8928518 0.0518206251 0.0556515721   13 113462892 113463088 197 - 0.095 0.434 2.811
ENSG00000150401 E011 24.9487054 0.0017255165 0.3009379069 0.541424889 13 113474124 113474196 73 - 1.419 1.348 -0.247
ENSG00000150401 E012 17.7927108 0.0089662089 0.6906472934 0.829483674 13 113474197 113474209 13 - 1.270 1.236 -0.118
ENSG00000150401 E013 22.2485745 0.0023254088 0.2205933538 0.454209264 13 113474210 113474254 45 - 1.385 1.294 -0.315
ENSG00000150401 E014 1.4044381 0.0187993234 0.0305255526 0.128918478 13 113480466 113480574 109 - 0.173 0.551 2.384
ENSG00000150401 E015 30.6767700 0.0014350301 0.6364623587 0.794650280 13 113480575 113480647 73 - 1.497 1.469 -0.094
ENSG00000150401 E016 27.6632211 0.0015995561 0.5794309475 0.756779261 13 113480648 113480743 96 - 1.458 1.423 -0.119
ENSG00000150401 E017 21.5329662 0.0021067670 0.0657636519 0.215651435 13 113483840 113483901 62 - 1.386 1.244 -0.493
ENSG00000150401 E018 24.4444073 0.0040326555 0.2215731062 0.455359896 13 113483902 113483962 61 - 1.420 1.330 -0.312
ENSG00000150401 E019 22.4478012 0.0083182609 0.5041836584 0.703724740 13 113483963 113484056 94 - 1.374 1.320 -0.186
ENSG00000150401 E020 16.6515547 0.0023273045 0.0599230690 0.202638749 13 113484057 113484196 140 - 1.161 1.322 0.567
ENSG00000150401 E021 4.1131130 0.0486788678 0.6660724143 0.813743503 13 113489090 113489173 84 - 0.671 0.751 0.332
ENSG00000150401 E022 5.7393421 0.0326937003 0.5463895869 0.733739427 13 113489174 113489253 80 - 0.841 0.753 -0.346
ENSG00000150401 E023 0.6901176 0.0214198361 0.1246956166   13 113490433 113490666 234 - 0.095 0.358 2.384
ENSG00000150401 E024 5.0198132 0.0062974715 0.3445191339 0.582098207 13 113490667 113490951 285 - 0.713 0.842 0.516