ENSG00000147601

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000276602 ENSG00000147601 HEK293_OSMI2_6hA HEK293_TMG_6hB TERF1 protein_coding protein_coding 22.22822 7.54562 42.62163 1.545649 0.2501398 2.496302 10.239353 3.911737 19.82458 1.0934114 1.00418131 2.338453 0.5365167 0.5037000 0.46503333 -0.03866667 0.9508443981 0.0007551758 FALSE  
ENST00000276603 ENSG00000147601 HEK293_OSMI2_6hA HEK293_TMG_6hB TERF1 protein_coding protein_coding 22.22822 7.54562 42.62163 1.545649 0.2501398 2.496302 2.561270 1.080223 2.47371 0.1443589 0.09399571 1.187873 0.1354667 0.1481333 0.05806667 -0.09006667 0.0007551758 0.0007551758 FALSE  
ENST00000518874 ENSG00000147601 HEK293_OSMI2_6hA HEK293_TMG_6hB TERF1 protein_coding protein_coding 22.22822 7.54562 42.62163 1.545649 0.2501398 2.496302 7.629509 1.865825 16.90564 0.5037733 0.78984832 3.172761 0.2404042 0.2547000 0.39666667 0.14196667 0.4652489222 0.0007551758 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000147601 E001 3.6843086 0.0073434434 0.7557052690 0.870046261 8 73008830 73008855 26 + 0.598 0.565 -0.150
ENSG00000147601 E002 5.5972821 0.0152228389 0.6782918808 0.821632301 8 73008856 73008859 4 + 0.743 0.699 -0.180
ENSG00000147601 E003 5.5972821 0.0152228389 0.6782918808 0.821632301 8 73008860 73008863 4 + 0.743 0.699 -0.180
ENSG00000147601 E004 18.0444795 0.0018289304 0.1079918408 0.295702396 8 73008864 73008876 13 + 1.211 1.068 -0.515
ENSG00000147601 E005 102.0315033 0.0005210473 0.0007527576 0.007883298 8 73008877 73008907 31 + 1.938 1.809 -0.434
ENSG00000147601 E006 215.0305489 0.0004537790 0.0054339385 0.036884277 8 73008908 73009205 298 + 2.246 2.187 -0.197
ENSG00000147601 E007 0.9930002 0.0911063156 0.1218936776   8 73009206 73012505 3300 + 0.167 0.477 2.089
ENSG00000147601 E008 0.4986023 0.0333054021 0.6619402922   8 73012856 73012931 76 + 0.167 0.000 -10.508
ENSG00000147601 E009 138.9055887 0.0024275614 0.0246054388 0.110999321 8 73013895 73013990 96 + 2.058 1.985 -0.245
ENSG00000147601 E010 160.8662429 0.0026585206 0.4714362251 0.681172559 8 73020684 73020805 122 + 2.109 2.104 -0.015
ENSG00000147601 E011 156.7668592 0.0003720384 0.4755346218 0.683874737 8 73022216 73022302 87 + 2.096 2.098 0.005
ENSG00000147601 E012 6.0050767 0.1019817067 0.0856314528 0.255727528 8 73022303 73024821 2519 + 0.673 1.013 1.326
ENSG00000147601 E013 212.9669725 0.0002702238 0.1480354672 0.359518825 8 73024822 73024971 150 + 2.234 2.218 -0.054
ENSG00000147601 E014 0.8023924 0.9302697010 0.3078083256   8 73024972 73025699 728 + 0.114 0.488 2.794
ENSG00000147601 E015 123.1155501 0.0008052967 0.0009792614 0.009751391 8 73026940 73026943 4 + 2.015 1.901 -0.382
ENSG00000147601 E016 212.4750746 0.0003200555 0.0207470487 0.098493933 8 73026944 73027052 109 + 2.239 2.196 -0.144
ENSG00000147601 E017 9.3824255 0.2519593075 0.5686150558 0.749248645 8 73027053 73028477 1425 + 0.944 0.819 -0.479
ENSG00000147601 E018 12.5042215 0.0029859036 0.0546957246 0.190648633 8 73028603 73029952 1350 + 1.070 0.846 -0.838
ENSG00000147601 E019 3.5172834 0.0068304356 0.7514129752 0.867651257 8 73029953 73030335 383 + 0.562 0.637 0.333
ENSG00000147601 E020 18.0040573 0.0020238777 0.0010311819 0.010150027 8 73030336 73030395 60 + 1.109 1.421 1.099
ENSG00000147601 E021 5.1501697 0.0198793406 0.8336608965 0.915820079 8 73030396 73030794 399 + 0.702 0.754 0.211
ENSG00000147601 E022 4.6993959 0.1418273275 0.0263553232 0.116352719 8 73030795 73030955 161 + 0.539 1.013 1.921
ENSG00000147601 E023 12.7620907 0.0462211452 0.0063926578 0.041648904 8 73030956 73031612 657 + 0.936 1.315 1.363
ENSG00000147601 E024 7.4167423 0.0055199262 0.1554468908 0.370109880 8 73031613 73032041 429 + 0.777 0.987 0.802
ENSG00000147601 E025 154.2238798 0.0004931828 0.0121722268 0.067158027 8 73032042 73032133 92 + 2.071 2.183 0.376
ENSG00000147601 E026 3.0717661 0.0074373369 0.5031099431 0.702913555 8 73038706 73038795 90 + 0.503 0.638 0.616
ENSG00000147601 E027 0.2027342 0.0484887165 0.1020720925   8 73038796 73038804 9 + 0.000 0.223 11.542
ENSG00000147601 E028 214.0675381 0.0004417369 0.2674644211 0.507124392 8 73039116 73039219 104 + 2.222 2.281 0.198
ENSG00000147601 E029 0.9500890 0.0440889141 0.8878572668   8 73039545 73039619 75 + 0.250 0.222 -0.228
ENSG00000147601 E030 0.5657866 0.0202418660 0.1848158784   8 73042011 73042778 768 + 0.118 0.368 2.097
ENSG00000147601 E031 590.3035978 0.0103474126 0.0234317830 0.107324101 8 73045961 73048123 2163 + 2.646 2.755 0.361