• ENSG00000147471
  • Isoform Switch

ENSG00000147471

Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000328195 ENSG00000147471 HEK293_OSMI2_6hA HEK293_TMG_6hB PLPBP protein_coding protein_coding 29.50086 13.37036 36.03435 1.131715 1.564476 1.429656 14.954643 8.164930 16.955873 1.7910887 0.3953902 1.0533574 0.55347500 0.6012 0.47163333 -0.129566667 6.810218e-01 5.629602e-22 FALSE TRUE
ENST00000521631 ENSG00000147471 HEK293_OSMI2_6hA HEK293_TMG_6hB PLPBP protein_coding retained_intron 29.50086 13.37036 36.03435 1.131715 1.564476 1.429656 2.002091 0.000000 6.120658 0.0000000 0.2040917 9.2598982 0.04904583 0.0000 0.17093333 0.170933333 5.629602e-22 5.629602e-22   FALSE
ENST00000523358 ENSG00000147471 HEK293_OSMI2_6hA HEK293_TMG_6hB PLPBP protein_coding protein_coding 29.50086 13.37036 36.03435 1.131715 1.564476 1.429656 5.780411 1.748717 4.978213 0.9032322 2.5267089 1.5039996 0.15540000 0.1398 0.13286667 -0.006933333 1.000000e+00 5.629602e-22 FALSE FALSE
MSTRG.31396.14 ENSG00000147471 HEK293_OSMI2_6hA HEK293_TMG_6hB PLPBP protein_coding   29.50086 13.37036 36.03435 1.131715 1.564476 1.429656 3.514074 1.836625 3.244528 0.6835847 0.1207247 0.8175576 0.13291250 0.1305 0.09066667 -0.039833333 9.074285e-01 5.629602e-22 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.