ENSG00000143614

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368655 ENSG00000143614 HEK293_OSMI2_6hA HEK293_TMG_6hB GATAD2B protein_coding protein_coding 15.86663 20.64409 16.34696 2.608234 0.3419342 -0.3365231 12.944013 18.9472 11.721998 2.124627 0.2528280 -0.6922971 0.81307083 0.9223333 0.7171000 -0.2052333 2.409652e-02 6.427604e-24 FALSE TRUE
MSTRG.2252.5 ENSG00000143614 HEK293_OSMI2_6hA HEK293_TMG_6hB GATAD2B protein_coding   15.86663 20.64409 16.34696 2.608234 0.3419342 -0.3365231 1.270594 0.0000 3.484393 0.000000 0.4266339 8.4488980 0.08361667 0.0000000 0.2126333 0.2126333 6.427604e-24 6.427604e-24 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000143614 E001 0.4644705 0.0218541211 0.266753969   1 153789030 153789782 753 -      
ENSG00000143614 E002 0.2027342 0.0440004979 1.000000000   1 153789938 153790076 139 -      
ENSG00000143614 E003 1904.4638718 1.9070989925 0.395606234 0.62488873 1 153804725 153809809 5085 -      
ENSG00000143614 E004 93.1468750 0.6080630159 0.469082960 0.67945272 1 153809810 153809916 107 -      
ENSG00000143614 E005 65.1907600 0.4924655518 0.489111185 0.69343122 1 153809917 153809947 31 -      
ENSG00000143614 E006 121.2786688 0.6493504245 0.358152473 0.59432984 1 153809948 153810096 149 -      
ENSG00000143614 E007 137.2161503 0.9630890978 0.490251899 0.69416484 1 153810097 153810310 214 -      
ENSG00000143614 E008 2.8367489 0.1270529164 0.039391977 0.15319724 1 153811596 153811730 135 -      
ENSG00000143614 E009 95.0819268 0.0005548662 0.867984618 0.93484846 1 153811731 153811844 114 -      
ENSG00000143614 E010 49.5690476 0.0038159094 0.409255296 0.63548911 1 153811845 153811848 4 -      
ENSG00000143614 E011 115.1443770 0.0213839174 0.113601142 0.30515514 1 153812022 153812132 111 -      
ENSG00000143614 E012 2.0016821 0.2042050608 0.827235254 0.91223099 1 153812133 153812275 143 -      
ENSG00000143614 E013 169.0392819 0.0256314213 0.020217429 0.09664737 1 153813250 153813452 203 -      
ENSG00000143614 E014 219.9908019 0.0482932833 0.066978749 0.21831696 1 153816273 153816585 313 -      
ENSG00000143614 E015 51.1478536 0.0760601179 0.227977015 0.46294108 1 153816586 153816588 3 -      
ENSG00000143614 E016 77.5127647 0.0969196340 0.394355812 0.62388269 1 153817372 153817419 48 -      
ENSG00000143614 E017 113.1571752 0.0600954087 0.163100709 0.38134003 1 153817420 153817542 123 -      
ENSG00000143614 E018 114.4934717 0.0523869387 0.050165447 0.18008808 1 153818040 153818171 132 -      
ENSG00000143614 E019 73.5647703 0.0396080873 0.031908590 0.13294606 1 153818791 153818824 34 -      
ENSG00000143614 E020 117.6082681 0.0363839707 0.008563475 0.05188640 1 153818825 153818922 98 -      
ENSG00000143614 E021 76.8641875 0.0248402870 0.001081795 0.01054371 1 153819606 153819623 18 -      
ENSG00000143614 E022 92.5892677 0.0343290437 0.005690887 0.03819180 1 153819624 153819676 53 -      
ENSG00000143614 E023 98.2457714 0.0326462997 0.002715857 0.02166501 1 153819677 153819735 59 -      
ENSG00000143614 E024 0.5227326 0.5474347889 0.887761287   1 153827558 153827610 53 -      
ENSG00000143614 E025 195.0966925 0.0357441555 0.001262334 0.01187804 1 153828013 153828257 245 -      
ENSG00000143614 E026 66.9314041 0.0185946006 0.001155167 0.01108641 1 153828258 153828265 8 -      
ENSG00000143614 E027 85.5674014 0.0247298007 0.001563074 0.01405964 1 153828266 153828348 83 -      
ENSG00000143614 E028 0.1426347 0.0306383085 0.245088344   1 153886424 153886521 98 -      
ENSG00000143614 E029 0.7310763 0.4976943605 0.616273253   1 153898856 153898916 61 -      
ENSG00000143614 E030 0.5530924 0.0395119687 1.000000000   1 153898917 153898982 66 -      
ENSG00000143614 E031 0.5668842 0.3343064211 1.000000000   1 153914674 153914740 67 -      
ENSG00000143614 E032 0.3926045 0.4769256890 0.502990459   1 153921839 153922030 192 -      
ENSG00000143614 E033 51.2118972 0.0187497531 0.005850181 0.03900676 1 153922733 153922972 240 -      
ENSG00000143614 E034 0.2027342 0.0440004979 1.000000000   1 153923299 153923360 62 -