ENSG00000138764

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316355 ENSG00000138764 HEK293_OSMI2_6hA HEK293_TMG_6hB CCNG2 protein_coding protein_coding 6.909278 2.123245 12.23601 0.1963773 1.062307 2.521189 2.6057600 1.2813624 3.5649967 0.1410579 0.5371221 1.469048 0.4167958 0.6063667 0.28873333 -0.317633333 0.003457561 0.002576878 FALSE TRUE
ENST00000395640 ENSG00000138764 HEK293_OSMI2_6hA HEK293_TMG_6hB CCNG2 protein_coding protein_coding 6.909278 2.123245 12.23601 0.1963773 1.062307 2.521189 0.3975833 0.0000000 0.5865519 0.0000000 0.2983860 5.898576 0.0889125 0.0000000 0.04706667 0.047066667 0.590015738 0.002576878 FALSE TRUE
ENST00000502280 ENSG00000138764 HEK293_OSMI2_6hA HEK293_TMG_6hB CCNG2 protein_coding protein_coding 6.909278 2.123245 12.23601 0.1963773 1.062307 2.521189 0.2972880 0.0000000 1.2509063 0.0000000 0.6285162 6.978317 0.0493625 0.0000000 0.11190000 0.111900000 0.555817760 0.002576878 FALSE TRUE
ENST00000509972 ENSG00000138764 HEK293_OSMI2_6hA HEK293_TMG_6hB CCNG2 protein_coding protein_coding 6.909278 2.123245 12.23601 0.1963773 1.062307 2.521189 2.4620470 0.8418831 4.8106386 0.1469756 0.3718327 2.500497 0.3206917 0.3936333 0.39710000 0.003466667 1.000000000 0.002576878 FALSE TRUE
ENST00000512918 ENSG00000138764 HEK293_OSMI2_6hA HEK293_TMG_6hB CCNG2 protein_coding protein_coding 6.909278 2.123245 12.23601 0.1963773 1.062307 2.521189 1.1441470 0.0000000 2.0229129 0.0000000 0.9576895 7.667405 0.1239500 0.0000000 0.15510000 0.155100000 0.002576878 0.002576878 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000138764 E001 3.0343917 0.0079654218 0.981280943 0.99241608 4 77157207 77157209 3 + 0.547 0.541 -0.028
ENSG00000138764 E002 3.0343917 0.0079654218 0.981280943 0.99241608 4 77157210 77157224 15 + 0.547 0.541 -0.028
ENSG00000138764 E003 1.5767104 0.0200198706 0.191930010 0.41930064 4 77157225 77157236 12 + 0.303 0.541 1.294
ENSG00000138764 E004 7.9298038 0.0038046535 0.034236041 0.13950453 4 77157237 77157369 133 + 0.805 1.061 0.965
ENSG00000138764 E005 22.8915925 0.0026902086 0.001833446 0.01593674 4 77157370 77157506 137 + 1.234 1.478 0.848
ENSG00000138764 E006 2.0413915 0.0342901943 0.206565868 0.43759837 4 77158297 77158355 59 + 0.479 0.210 -1.697
ENSG00000138764 E007 2.1261394 0.1146474113 0.038979923 0.15213475 4 77158356 77158425 70 + 0.521 0.000 -13.757
ENSG00000138764 E008 2.6261468 0.0122149021 0.313654054 0.55387570 4 77158426 77158451 26 + 0.547 0.349 -1.028
ENSG00000138764 E009 4.7937720 0.0061932549 0.529081658 0.72136995 4 77158452 77158532 81 + 0.717 0.612 -0.445
ENSG00000138764 E010 55.9359476 0.0006696082 0.462184514 0.67463988 4 77158533 77158670 138 + 1.665 1.703 0.128
ENSG00000138764 E011 62.7788828 0.0009127134 0.654864663 0.80665786 4 77159367 77159504 138 + 1.729 1.703 -0.087
ENSG00000138764 E012 90.5753609 0.0042737376 0.205291710 0.43623782 4 77160721 77160971 251 + 1.893 1.823 -0.236
ENSG00000138764 E013 54.4052893 0.0044109539 0.238765095 0.47520232 4 77161480 77161558 79 + 1.675 1.595 -0.272
ENSG00000138764 E014 67.3327037 0.0143910222 0.434273226 0.65445196 4 77161649 77161747 99 + 1.765 1.697 -0.230
ENSG00000138764 E015 106.2135229 0.0004803811 0.536035197 0.72635451 4 77164274 77164479 206 + 1.956 1.930 -0.089
ENSG00000138764 E016 15.8697467 0.0021340686 0.283686486 0.52412466 4 77164480 77165010 531 + 1.175 1.061 -0.411
ENSG00000138764 E017 310.2098149 0.0008673769 0.158198410 0.37408071 4 77165801 77170060 4260 + 2.406 2.432 0.089
ENSG00000138764 E018 0.3447487 0.4266610260 0.058779456   4 77178956 77179066 111 + 0.000 0.354 12.271
ENSG00000138764 E019 0.0000000       4 77185097 77185410 314 +      
ENSG00000138764 E020 0.0000000       4 77187764 77187807 44 +      
ENSG00000138764 E021 0.0000000       4 77192211 77192267 57 +      
ENSG00000138764 E022 0.0000000       4 77384637 77384767 131 +      
ENSG00000138764 E023 0.0000000       4 77431726 77431870 145 +      
ENSG00000138764 E024 0.1308682 0.0326491905 0.117606177   4 77432240 77432433 194 + 0.000 0.209 12.224
ENSG00000138764 E025 0.0000000       4 77433207 77433388 182 +