• ENSG00000137770
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000137770

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000260327 ENSG00000137770 HEK293_OSMI2_6hA HEK293_TMG_6hB CTDSPL2 protein_coding protein_coding 13.49443 1.212103 28.49445 0.3321133 0.3948919 4.54375 5.25701037 0.73833834 11.66808863 0.37472149 0.66085365 3.9639697 0.45869167 0.4775333 0.4103000000 -0.067233333 9.848773e-01 8.599626e-13 FALSE TRUE
ENST00000558791 ENSG00000137770 HEK293_OSMI2_6hA HEK293_TMG_6hB CTDSPL2 protein_coding protein_coding 13.49443 1.212103 28.49445 0.3321133 0.3948919 4.54375 5.04742316 0.00000000 12.14352045 0.00000000 0.68649355 10.2471586 0.20617083 0.0000000 0.4257333333 0.425733333 8.599626e-13 8.599626e-13 FALSE FALSE
ENST00000558966 ENSG00000137770 HEK293_OSMI2_6hA HEK293_TMG_6hB CTDSPL2 protein_coding protein_coding 13.49443 1.212103 28.49445 0.3321133 0.3948919 4.54375 0.08197614 0.13902558 0.02357699 0.13902558 0.02357699 -2.1500151 0.06563750 0.2521000 0.0008333333 -0.251266667 6.889613e-01 8.599626e-13 FALSE TRUE
ENST00000559175 ENSG00000137770 HEK293_OSMI2_6hA HEK293_TMG_6hB CTDSPL2 protein_coding retained_intron 13.49443 1.212103 28.49445 0.3321133 0.3948919 4.54375 0.07539932 0.07479923 0.12162554 0.01423876 0.03479015 0.6343164 0.02627083 0.0793000 0.0042333333 -0.075066667 2.056487e-03 8.599626e-13 TRUE FALSE
MSTRG.10678.1 ENSG00000137770 HEK293_OSMI2_6hA HEK293_TMG_6hB CTDSPL2 protein_coding   13.49443 1.212103 28.49445 0.3321133 0.3948919 4.54375 1.85989662 0.15840103 2.90941300 0.08053669 0.54142600 4.1157054 0.12363333 0.1032667 0.1017000000 -0.001566667 9.723814e-01 8.599626e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000137770 E001 7.4627988 0.0039612053 9.452472e-01 9.748966e-01 15 44427614 44427621 8 + 0.674 0.664 -0.042
ENSG00000137770 E002 8.1545818 0.0041229908 3.996650e-01 6.279826e-01 15 44427622 44427628 7 + 0.690 0.846 0.629
ENSG00000137770 E003 11.0244215 0.0030391933 2.856529e-01 5.262577e-01 15 44427629 44427641 13 + 0.798 0.975 0.676
ENSG00000137770 E004 41.6444197 0.0014821065 3.581857e-01 5.943618e-01 15 44427642 44427692 51 + 1.348 1.252 -0.336
ENSG00000137770 E005 61.2170047 0.0010014272 9.307356e-02 2.694286e-01 15 44427693 44427772 80 + 1.511 1.356 -0.535
ENSG00000137770 E006 0.4868358 0.2292067415 1.511679e-01   15 44427793 44427807 15 + 0.070 0.340 2.757
ENSG00000137770 E007 0.3088520 0.0260537725 5.983407e-02   15 44427808 44427813 6 + 0.036 0.343 3.796
ENSG00000137770 E008 0.6482515 0.0275011436 2.135875e-01   15 44427814 44427893 80 + 0.100 0.343 2.209
ENSG00000137770 E009 0.3088520 0.0260537725 5.983407e-02   15 44427894 44428005 112 + 0.036 0.343 3.796
ENSG00000137770 E010 0.1614157 0.0372460832 4.349582e-01   15 44428006 44428095 90 + 0.036 0.000 -6.859
ENSG00000137770 E011 41.3439468 0.0059451524 6.037524e-02 2.036604e-01 15 44458991 44459002 12 + 1.348 1.116 -0.818
ENSG00000137770 E012 123.3421692 0.0014255219 2.037390e-04 2.716400e-03 15 44459003 44459200 198 + 1.813 1.540 -0.925
ENSG00000137770 E013 0.1426347 0.0352287128 4.348371e-01   15 44470469 44470574 106 + 0.036 0.000 -6.877
ENSG00000137770 E014 107.2838559 0.0018208105 1.660092e-03 1.474409e-02 15 44484224 44484362 139 + 1.754 1.509 -0.830
ENSG00000137770 E015 51.9007827 0.0007557947 2.580128e-01 4.967468e-01 15 44486551 44486553 3 + 1.440 1.332 -0.374
ENSG00000137770 E016 116.7295721 0.0003889154 5.708986e-03 3.828452e-02 15 44486554 44486700 147 + 1.787 1.597 -0.646
ENSG00000137770 E017 137.5449983 0.0003597427 1.627042e-03 1.451028e-02 15 44490784 44490991 208 + 1.859 1.658 -0.680
ENSG00000137770 E018 48.2073025 0.0014701735 1.840031e-01 4.091696e-01 15 44490992 44490999 8 + 1.415 1.280 -0.468
ENSG00000137770 E019 78.0235052 0.0008747221 4.482272e-01 6.644227e-01 15 44496380 44496458 79 + 1.610 1.555 -0.189
ENSG00000137770 E020 90.2317857 0.0019713366 7.293081e-01 8.538544e-01 15 44497027 44497138 112 + 1.668 1.647 -0.073
ENSG00000137770 E021 78.2387801 0.0005593268 5.179424e-02 1.839790e-01 15 44499727 44499813 87 + 1.617 1.458 -0.544
ENSG00000137770 E022 2.7525892 0.0782056730 1.745481e-01 3.965775e-01 15 44501962 44502048 87 + 0.359 0.661 1.479
ENSG00000137770 E023 4.4647500 0.0210575023 4.841298e-01 6.898750e-01 15 44503424 44503879 456 + 0.523 0.343 -0.958
ENSG00000137770 E024 74.3721571 0.0004973289 2.941336e-01 5.347105e-01 15 44514598 44514660 63 + 1.591 1.509 -0.278
ENSG00000137770 E025 75.7651592 0.0005806020 5.049252e-01 7.042718e-01 15 44514765 44514844 80 + 1.592 1.647 0.185
ENSG00000137770 E026 3.0671521 0.0148361527 1.767671e-01 3.994492e-01 15 44518654 44518864 211 + 0.377 0.665 1.389
ENSG00000137770 E027 69.3278140 0.0005937397 2.293864e-01 4.644256e-01 15 44519169 44519223 55 + 1.551 1.647 0.326
ENSG00000137770 E028 63.2991817 0.0007303448 8.307952e-01 9.142332e-01 15 44519224 44519295 72 + 1.518 1.540 0.076
ENSG00000137770 E029 2.2627842 0.1159859092 3.822380e-01 6.140474e-01 15 44519637 44521263 1627 + 0.312 0.528 1.171
ENSG00000137770 E030 0.3559677 0.5392323695 6.607526e-01   15 44521264 44521310 47 + 0.071 0.001 -7.141
ENSG00000137770 E031 78.7055471 0.0025325258 5.520047e-01 7.376989e-01 15 44521311 44521406 96 + 1.609 1.658 0.167
ENSG00000137770 E032 768.2122037 0.0003070471 2.620560e-13 3.012652e-11 15 44524109 44529038 4930 + 2.578 2.718 0.465