• ENSG00000130751
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000130751

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000439365 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding protein_coding 19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 2.7694960 4.7592608 0.4762136 1.7690261 0.2534239 -3.294103 0.11841667 0.15320000 0.06780000 -0.08540000 7.045700e-01 5.369949e-10 FALSE TRUE
ENST00000594257 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding nonsense_mediated_decay 19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 0.7205332 0.3510258 0.7652316 0.3510258 0.3850872 1.102525 0.04051250 0.02176667 0.10586667 0.08410000 5.626817e-01 5.369949e-10 FALSE FALSE
ENST00000601169 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding retained_intron 19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 1.7390526 2.2445643 0.9500942 0.4908069 0.1208034 -1.231601 0.10302500 0.08060000 0.13223333 0.05163333 3.752788e-01 5.369949e-10 FALSE TRUE
ENST00000602189 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding protein_coding 19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 1.3113528 2.3767291 0.4593280 0.6755938 0.3995255 -2.346366 0.06565833 0.08100000 0.06113333 -0.01986667 7.197687e-01 5.369949e-10 FALSE TRUE
ENST00000602212 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding protein_coding 19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 2.4128715 2.3367853 0.8129083 1.0671173 0.4723075 -1.511882 0.13737917 0.07350000 0.11483333 0.04133333 1.000000e+00 5.369949e-10 FALSE TRUE
MSTRG.17389.17 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding   19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 0.3474688 0.0000000 0.5771208 0.0000000 0.1671785 5.875585 0.02259167 0.00000000 0.07913333 0.07913333 5.369949e-10 5.369949e-10 FALSE TRUE
MSTRG.17389.18 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding   19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 2.1698846 3.5694158 0.7107624 0.1261899 0.7107624 -2.312128 0.10301250 0.14116667 0.09743333 -0.04373333 4.531166e-01 5.369949e-10 FALSE TRUE
MSTRG.17389.9 ENSG00000130751 HEK293_OSMI2_6hA HEK293_TMG_6hB NPAS1 protein_coding   19.51807 28.13329 7.245667 6.152999 0.2126588 -1.955611 1.1224008 2.7942052 0.0000000 0.8252652 0.0000000 -8.131448 0.05014167 0.09463333 0.00000000 -0.09463333 1.212196e-09 5.369949e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000130751 E001 0.0000000       19 47019801 47019806 6 +      
ENSG00000130751 E002 1.5114157 0.4240751704 0.4185031001 0.642517692 19 47019807 47019836 30 + 0.001 0.370 9.337
ENSG00000130751 E003 1.8036996 0.4077498560 0.8747808672 0.938641877 19 47019837 47019838 2 + 0.249 0.391 0.916
ENSG00000130751 E004 2.4219511 0.1298987059 0.9015766311 0.952676483 19 47019839 47019844 6 + 0.404 0.465 0.318
ENSG00000130751 E005 3.0172898 0.1155040699 0.6864565730 0.826780068 19 47019845 47019845 1 + 0.404 0.535 0.659
ENSG00000130751 E006 3.7260008 0.0319629991 0.3596466513 0.595545355 19 47019846 47019847 2 + 0.405 0.607 0.983
ENSG00000130751 E007 4.6549418 0.0352736412 0.2085923063 0.440176032 19 47019848 47019848 1 + 0.405 0.684 1.313
ENSG00000130751 E008 12.2848367 0.0111275240 0.0022948682 0.019018222 19 47019849 47019869 21 + 0.520 1.051 2.148
ENSG00000130751 E009 16.8619954 0.0203352816 0.0028784104 0.022677903 19 47019870 47019898 29 + 0.685 1.170 1.844
ENSG00000130751 E010 48.4134686 0.0009168797 0.0054090581 0.036741829 19 47019899 47019997 99 + 1.369 1.581 0.732
ENSG00000130751 E011 0.3336024 0.0244411696 1.0000000000   19 47020886 47021005 120 + 0.000 0.104 9.734
ENSG00000130751 E012 71.7565804 0.0193414549 0.2299527593 0.465124871 19 47021006 47021169 164 + 1.625 1.727 0.347
ENSG00000130751 E013 60.2754675 0.0008270956 0.1928406596 0.420594882 19 47021612 47021847 236 + 1.571 1.654 0.281
ENSG00000130751 E014 42.3692466 0.0039335869 0.4413828429 0.659662816 19 47032278 47032351 74 + 1.447 1.499 0.181
ENSG00000130751 E015 70.4426192 0.0019958577 0.0405142931 0.156082185 19 47032643 47032732 90 + 1.813 1.691 -0.412
ENSG00000130751 E016 10.7618166 0.1039974442 0.4781463196 0.685894622 19 47035329 47035331 3 + 1.078 0.902 -0.649
ENSG00000130751 E017 13.1921924 0.0390724649 0.4326073254 0.653199675 19 47035332 47035347 16 + 1.128 0.988 -0.511
ENSG00000130751 E018 11.3670601 0.0034106614 0.6246037201 0.787099929 19 47035348 47035349 2 + 1.011 0.945 -0.244
ENSG00000130751 E019 12.6929251 0.0030523255 0.5127008297 0.709974176 19 47035350 47035358 9 + 1.072 0.989 -0.302
ENSG00000130751 E020 11.5016547 0.0029153076 0.0060918415 0.040176603 19 47035860 47035888 29 + 1.216 0.903 -1.139
ENSG00000130751 E021 15.0937660 0.0523371241 0.1268177795 0.326722632 19 47035889 47035963 75 + 1.274 1.026 -0.887
ENSG00000130751 E022 139.5575304 0.0003950792 0.9183061161 0.961360188 19 47035964 47036129 166 + 2.012 2.005 -0.022
ENSG00000130751 E023 56.5745191 0.0009408109 0.3496491443 0.586952539 19 47039036 47039076 41 + 1.571 1.630 0.202
ENSG00000130751 E024 82.8796449 0.0006139668 0.9766690289 0.990076910 19 47039077 47039151 75 + 1.786 1.784 -0.009
ENSG00000130751 E025 6.3077521 0.0051714668 0.6600543344 0.810027371 19 47039404 47039406 3 + 0.686 0.757 0.291
ENSG00000130751 E026 119.6401464 0.0007222870 0.7171982677 0.846400920 19 47039407 47039564 158 + 1.953 1.935 -0.059
ENSG00000130751 E027 144.3313105 0.0004941054 0.0341888286 0.139364140 19 47040444 47040550 107 + 2.087 2.003 -0.281
ENSG00000130751 E028 12.5807333 0.1288407697 0.0112542517 0.063420188 19 47040551 47040758 208 + 1.392 0.871 -1.880
ENSG00000130751 E029 57.1751919 0.0006642304 0.0055325942 0.037382102 19 47040978 47041024 47 + 1.758 1.596 -0.552
ENSG00000130751 E030 121.2143399 0.0004008899 0.1997981121 0.429416121 19 47041025 47041125 101 + 1.992 1.937 -0.185
ENSG00000130751 E031 141.8108706 0.0039415083 0.9589724465 0.981382854 19 47042810 47042904 95 + 2.006 2.005 -0.004
ENSG00000130751 E032 17.0975606 0.0021945527 0.6207045075 0.784317370 19 47045135 47045190 56 + 1.072 1.127 0.200
ENSG00000130751 E033 241.2941292 0.0002950822 0.0006653756 0.007141706 19 47045191 47045775 585 + 2.148 2.253 0.350