• ENSG00000130741
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000130741

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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TableFilter v0.7.3

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000253039 ENSG00000130741 HEK293_OSMI2_6hA HEK293_TMG_6hB EIF2S3 protein_coding protein_coding 139.5567 69.41853 205.1769 13.26145 3.516731 1.563338 94.87378 54.849812 125.18895 14.0288571 3.917742 1.190401 0.7136083 0.7641667 0.6103333 -0.1538333 0.420554854 0.002076034 FALSE TRUE
ENST00000460032 ENSG00000130741 HEK293_OSMI2_6hA HEK293_TMG_6hB EIF2S3 protein_coding processed_transcript 139.5567 69.41853 205.1769 13.26145 3.516731 1.563338 12.29289 6.250804 21.85521 1.2844350 1.945334 1.804218 0.0954875 0.1077000 0.1064000 -0.0013000 0.958527467 0.002076034   FALSE
MSTRG.34026.4 ENSG00000130741 HEK293_OSMI2_6hA HEK293_TMG_6hB EIF2S3 protein_coding   139.5567 69.41853 205.1769 13.26145 3.516731 1.563338 19.27326 3.685695 40.57979 0.7135513 2.244438 3.457199 0.1066708 0.0574000 0.1978000 0.1404000 0.002076034 0.002076034 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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TableFilter v0.7.3

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©2015-2025 Max Guglielmi
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Page of 3
groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000130741 E001 4.383016 2.384747e-01 1.143718e-01 3.064283e-01 X 24054679 24054680 2 + 0.559 0.930 1.519
ENSG00000130741 E002 6.753185 3.756745e-01 1.804226e-01 4.045459e-01 X 24054681 24054707 27 + 0.715 1.081 1.399
ENSG00000130741 E003 11.996405 6.229931e-01 4.348002e-01 6.548400e-01 X 24054708 24054739 32 + 1.004 1.219 0.773
ENSG00000130741 E004 15.234702 6.230040e-01 4.852466e-01 6.907227e-01 X 24054740 24054759 20 + 1.129 1.267 0.487
ENSG00000130741 E005 50.894588 9.024338e-01 4.878608e-01 6.925777e-01 X 24054760 24054945 186 + 1.633 1.764 0.444
ENSG00000130741 E006 32.273077 7.781144e-01 5.574615e-01 7.414526e-01 X 24054946 24054955 10 + 1.452 1.551 0.342
ENSG00000130741 E007 73.869256 1.334872e+00 8.278164e-01 9.125174e-01 X 24054956 24054970 15 + 1.858 1.774 -0.282
ENSG00000130741 E008 429.775943 7.419854e-01 4.773383e-01 6.852559e-01 X 24054971 24055037 67 + 2.551 2.682 0.437
ENSG00000130741 E009 628.235800 8.852490e-02 6.176847e-01 7.822359e-01 X 24055615 24055678 64 + 2.743 2.795 0.173
ENSG00000130741 E010 973.408884 1.664815e-02 9.778569e-01 9.907123e-01 X 24057421 24057548 128 + 2.941 2.966 0.084
ENSG00000130741 E011 426.680273 9.551325e-04 1.611186e-01 3.784763e-01 X 24057633 24057641 9 + 2.592 2.594 0.009
ENSG00000130741 E012 992.985771 8.281574e-05 3.963823e-06 9.426528e-05 X 24057642 24057754 113 + 2.964 2.944 -0.068
ENSG00000130741 E013 825.794373 2.339720e-03 2.039162e-02 9.728264e-02 X 24060088 24060182 95 + 2.884 2.859 -0.085
ENSG00000130741 E014 1.139839 2.370237e-01 9.977504e-02   X 24060183 24060479 297 + 0.389 0.000 -10.776
ENSG00000130741 E015 1.119875 1.537876e-02 3.255800e-01   X 24061890 24061930 41 + 0.349 0.178 -1.287
ENSG00000130741 E016 2.732742 2.044424e-01 4.032887e-01 6.309323e-01 X 24061931 24062009 79 + 0.588 0.405 -0.901
ENSG00000130741 E017 1006.687307 3.108631e-03 3.070125e-03 2.383441e-02 X 24062416 24062574 159 + 2.978 2.925 -0.174
ENSG00000130741 E018 2.759534 8.940985e-03 5.150118e-01 7.116560e-01 X 24062575 24062626 52 + 0.566 0.480 -0.406
ENSG00000130741 E019 757.597958 9.259769e-04 1.384592e-04 1.962406e-03 X 24064201 24064335 135 + 2.852 2.811 -0.136
ENSG00000130741 E020 600.296481 3.693061e-04 1.810689e-04 2.460367e-03 X 24065998 24066092 95 + 2.749 2.718 -0.102
ENSG00000130741 E021 1092.170401 2.614752e-03 2.086351e-01 4.402157e-01 X 24067964 24068108 145 + 2.998 3.000 0.007
ENSG00000130741 E022 1156.352761 2.585030e-03 6.184394e-01 7.827541e-01 X 24071558 24071712 155 + 3.017 3.039 0.074
ENSG00000130741 E023 482.551059 2.426789e-03 2.485610e-01 4.863403e-01 X 24071713 24071727 15 + 2.644 2.648 0.016
ENSG00000130741 E024 922.142287 2.104394e-03 5.013966e-01 7.017998e-01 X 24073091 24073181 91 + 2.919 2.939 0.066
ENSG00000130741 E025 918.413359 1.334916e-03 8.468872e-03 5.147357e-02 X 24073182 24073261 80 + 2.929 2.909 -0.068
ENSG00000130741 E026 537.857868 6.812014e-04 2.531481e-04 3.252904e-03 X 24073262 24073263 2 + 2.703 2.663 -0.132
ENSG00000130741 E027 92.104161 1.214844e-01 5.087361e-01 7.069916e-01 X 24073264 24073411 148 + 1.950 1.875 -0.250
ENSG00000130741 E028 32.354713 1.108230e-01 4.725816e-01 6.819271e-01 X 24073412 24073528 117 + 1.509 1.415 -0.324
ENSG00000130741 E029 2296.619931 1.860487e-03 1.782299e-02 8.843693e-02 X 24076722 24077343 622 + 3.295 3.378 0.275
ENSG00000130741 E030 2634.537668 3.826227e-03 2.528213e-05 4.657216e-04 X 24077344 24078810 1467 + 3.328 3.485 0.520