• ENSG00000124459
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000124459

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000269973 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding protein_coding 5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 1.07555848 0.00000000 2.1018258 0.00000000 0.14937377 7.7223470 0.14795417 0.000000000 0.21586667 0.21586667 2.989310e-12 2.98931e-12 FALSE TRUE
ENST00000615985 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding protein_coding 5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 1.41151802 1.14169257 2.2598365 0.23755945 0.33429688 0.9788327 0.31011250 0.394866667 0.23276667 -0.16210000 1.595853e-01 2.98931e-12 FALSE TRUE
MSTRG.17268.1 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding   5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 0.51430974 0.09910950 0.6805906 0.09910950 0.12966540 2.6620540 0.07555417 0.030533333 0.06923333 0.03870000 5.977708e-01 2.98931e-12 FALSE TRUE
MSTRG.17268.2 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding   5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 0.88108197 0.84192309 1.0906303 0.20351447 0.66586460 0.3695349 0.16457917 0.290566667 0.10733333 -0.18323333 5.849386e-01 2.98931e-12 FALSE TRUE
MSTRG.17268.4 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding   5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 0.44674952 0.06580150 1.0644250 0.06580150 0.56624250 3.8251946 0.07377917 0.020266667 0.11446667 0.09420000 7.590138e-01 2.98931e-12 FALSE TRUE
MSTRG.17268.6 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding   5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 0.04723472 0.19737639 0.0000000 0.11408846 0.00000000 -4.3741797 0.01588333 0.073533333 0.00000000 -0.07353333 1.598322e-01 2.98931e-12 FALSE TRUE
MSTRG.17268.9 ENSG00000124459 HEK293_OSMI2_6hA HEK293_TMG_6hB ZNF45 protein_coding   5.789446 2.888724 9.715916 0.5880539 0.4894116 1.746416 0.33118272 0.01321697 0.7365053 0.01321697 0.08597978 5.0069007 0.04528750 0.004066667 0.07686667 0.07280000 6.278413e-03 2.98931e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000124459 E001 2.280692 0.0099020987 0.37805515 0.61057393 19 43912511 43912517 7 - 0.427 0.580 0.743
ENSG00000124459 E002 6.062645 0.0052858464 0.02341893 0.10729302 19 43912518 43912623 106 - 0.707 0.998 1.131
ENSG00000124459 E003 3.555378 0.0069305198 0.04016080 0.15512211 19 43912624 43912630 7 - 0.509 0.819 1.327
ENSG00000124459 E004 6.544867 0.0050292690 0.10282677 0.28682289 19 43912631 43912680 50 - 0.766 0.973 0.797
ENSG00000124459 E005 9.741192 0.0049486635 0.91320446 0.95872439 19 43912681 43912712 32 - 0.988 0.973 -0.057
ENSG00000124459 E006 62.427291 0.0006926468 0.02794877 0.12113582 19 43912713 43913128 416 - 1.719 1.822 0.350
ENSG00000124459 E007 106.992882 0.0038658556 0.15540188 0.37004940 19 43913129 43913624 496 - 1.954 2.018 0.214
ENSG00000124459 E008 58.122335 0.0007207503 0.13666081 0.34239904 19 43913625 43913792 168 - 1.695 1.768 0.248
ENSG00000124459 E009 197.909220 0.0004387202 0.09942261 0.28072932 19 43913793 43914940 1148 - 2.229 2.271 0.139
ENSG00000124459 E010 55.671438 0.0006986695 0.01444893 0.07606228 19 43914941 43915200 260 - 1.728 1.591 -0.463
ENSG00000124459 E011 34.615116 0.0035185013 0.48075954 0.68761979 19 43918870 43918962 93 - 1.506 1.454 -0.179
ENSG00000124459 E012 42.845198 0.0052438219 0.14362458 0.35280919 19 43919573 43919699 127 - 1.605 1.502 -0.351
ENSG00000124459 E013 4.414167 0.0092284705 0.07757696 0.23999184 19 43919700 43919762 63 - 0.738 0.428 -1.413
ENSG00000124459 E014 26.236105 0.0016715628 0.00334400 0.02544569 19 43922171 43922217 47 - 1.426 1.176 -0.876
ENSG00000124459 E015 1.177761 0.0153787590 0.82324166   19 43922218 43922287 70 - 0.286 0.327 0.269
ENSG00000124459 E016 33.117414 0.0128361582 0.15515096 0.36965405 19 43924238 43924310 73 - 1.501 1.370 -0.452
ENSG00000124459 E017 0.308852 0.0265313685 0.41941547   19 43924311 43924312 2 - 0.074 0.193 1.585
ENSG00000124459 E018 41.677789 0.0102113988 0.25181125 0.48984915 19 43924402 43924561 160 - 1.590 1.495 -0.326
ENSG00000124459 E019 32.920366 0.0033938699 0.42625784 0.64823277 19 43925325 43925458 134 - 1.486 1.427 -0.203
ENSG00000124459 E020 3.718237 0.0097998267 0.16966834 0.39006858 19 43929918 43929956 39 - 0.674 0.428 -1.147
ENSG00000124459 E021 4.019266 0.0060460061 0.56862809 0.74926000 19 43929957 43929997 41 - 0.674 0.580 -0.411
ENSG00000124459 E022 3.107115 0.0076127817 0.89100686 0.94715945 19 43929998 43930000 3 - 0.557 0.580 0.103
ENSG00000124459 E023 16.188326 0.0026158127 0.32358098 0.56290071 19 43931247 43931365 119 - 1.158 1.250 0.323
ENSG00000124459 E024 1.867589 0.0172287894 0.98308893 0.99334272 19 43932403 43932603 201 - 0.427 0.428 0.006
ENSG00000124459 E025 10.098997 0.0036098527 0.76630969 0.87637401 19 43932604 43932607 4 - 0.988 1.022 0.122
ENSG00000124459 E026 22.558610 0.0016008023 0.14697402 0.35797159 19 43932608 43932690 83 - 1.346 1.222 -0.437
ENSG00000124459 E027 33.293466 0.0292010174 0.30059028 0.54107461 19 43934426 43934694 269 - 1.510 1.392 -0.404
ENSG00000124459 E028 2.028817 0.0106786680 0.63735714 0.79527632 19 43934695 43934727 33 - 0.427 0.510 0.420
ENSG00000124459 E029 19.492481 0.6481702286 0.54370118 0.73172825 19 43934924 43935229 306 - 1.241 1.298 0.201
ENSG00000124459 E030 6.282981 0.4274240961 0.70030718 0.83583368 19 43935230 43935294 65 - 0.812 0.834 0.085