ENSG00000120885

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000405140	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	0.15736000	0.1298110	0.1995136	0.1298110	0.1031166	0.5835661	0.01665833	0.005233333	0.06460000	0.05936667	5.038457e-01	4.356299e-05	FALSE	TRUE
ENST00000519472	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	2.76754719	7.5532036	0.5707077	2.1748783	0.5707077	-3.7031133	0.21795833	0.357566667	0.11713333	-0.24043333	3.057888e-01	4.356299e-05	FALSE	FALSE
ENST00000521770	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	0.55101691	0.3764212	0.4352500	0.3764212	0.4352500	0.2044415	0.06254583	0.015200000	0.10390000	0.08870000	9.044634e-01	4.356299e-05	FALSE	TRUE
ENST00000522098	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	2.89784617	5.3096400	0.4770612	0.6190137	0.2412390	-3.4491537	0.25285417	0.264466667	0.14606667	-0.11840000	7.500656e-01	4.356299e-05	FALSE	FALSE
ENST00000522502	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	retained_intron	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	0.21646472	0.0000000	0.4544533	0.0000000	0.4544533	5.5374616	0.02838333	0.000000000	0.09326667	0.09326667	6.665856e-01	4.356299e-05	FALSE	FALSE
ENST00000523589	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	0.07714278	0.0000000	0.6171422	0.0000000	0.6171422	5.9707207	0.01841250	0.000000000	0.14730000	0.14730000	7.148574e-01	4.356299e-05	FALSE	FALSE
ENST00000560566	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding	protein_coding	11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	0.91439018	1.7911074	0.0000000	0.2085035	0.0000000	-7.4927404	0.08054167	0.093633333	0.00000000	-0.09363333	4.356299e-05	4.356299e-05	FALSE	TRUE
MSTRG.31310.3	ENSG00000120885	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CLU	protein_coding		11.11954	20.33748	3.88255	3.099407	0.6773261	-2.386062	3.42253753	4.9728399	1.1050612	0.9321020	0.5539540	-2.1598453	0.31150000	0.253133333	0.32286667	0.06973333	1.000000e+00	4.356299e-05	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 36
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000120885	E001	0.0000000				8	27596917	27597807	891	-
ENSG00000120885	E002	0.8984613	0.0520801469	0.21911274		8	27597808	27597995	188	-	0.394	0.154	-1.788
ENSG00000120885	E003	17.1782432	0.0026333724	0.96214941	0.9831070	8	27597996	27598142	147	-	1.131	1.136	0.018
ENSG00000120885	E004	31.5496112	0.0014487131	0.22663579	0.4613371	8	27598143	27598250	108	-	1.463	1.369	-0.322
ENSG00000120885	E005	34.5663670	0.0015403957	0.28119333	0.5214789	8	27598460	27598536	77	-	1.495	1.416	-0.271
ENSG00000120885	E006	41.8090294	0.0051283143	0.72953039	0.8539628	8	27598537	27598635	99	-	1.525	1.503	-0.074
ENSG00000120885	E007	0.7569420	0.0440793135	0.20770553		8	27598636	27599779	1144	-	0.394	0.153	-1.809
ENSG00000120885	E008	60.2024815	0.0051598469	0.93948644	0.9719602	8	27599780	27600009	230	-	1.662	1.660	-0.007
ENSG00000120885	E009	0.0000000				8	27600010	27600015	6	-
ENSG00000120885	E010	0.0000000				8	27604218	27604290	73	-
ENSG00000120885	E011	27.7021038	0.0015999980	0.64584626	0.8007381	8	27604291	27604309	19	-	1.364	1.325	-0.134
ENSG00000120885	E012	39.9849697	0.0010399180	0.83389927	0.9159753	8	27604310	27604365	56	-	1.495	1.480	-0.050
ENSG00000120885	E013	32.1195558	0.0021702741	0.68458749	0.8256775	8	27604366	27604395	30	-	1.364	1.399	0.122
ENSG00000120885	E014	60.0144014	0.0008374415	0.12405045	0.3221491	8	27604924	27605069	146	-	1.570	1.665	0.325
ENSG00000120885	E015	36.5971782	0.0042872596	0.06821529	0.2210703	8	27605070	27605140	71	-	1.305	1.460	0.539
ENSG00000120885	E016	27.1307671	0.0037556924	0.09649651	0.2756350	8	27605141	27605171	31	-	1.176	1.338	0.567
ENSG00000120885	E017	47.2404235	0.0008285975	0.41836224	0.6423885	8	27605172	27605335	164	-	1.505	1.561	0.192
ENSG00000120885	E018	0.3336024	0.0274424043	1.00000000		8	27605336	27605339	4	-	0.000	0.108	9.553
ENSG00000120885	E019	17.5082528	0.0052835332	0.40380631	0.6313706	8	27606354	27606363	10	-	1.217	1.134	-0.296
ENSG00000120885	E020	19.0306950	0.0084816032	0.36842088	0.6027644	8	27606364	27606381	18	-	1.255	1.167	-0.310
ENSG00000120885	E021	46.5196800	0.0038402803	0.06957716	0.2239099	8	27606382	27606524	143	-	1.649	1.528	-0.412
ENSG00000120885	E022	0.5649788	0.0245359591	0.58990811		8	27608541	27608936	396	-	0.000	0.194	10.547
ENSG00000120885	E023	0.1308682	0.0326491905	1.00000000		8	27608937	27608937	1	-	0.000	0.057	8.550
ENSG00000120885	E024	54.2082541	0.0011274799	0.59805589	0.7689604	8	27608938	27609086	149	-	1.634	1.601	-0.111
ENSG00000120885	E025	23.4359834	0.0020766781	0.50125446	0.7016819	8	27610475	27610475	1	-	1.305	1.243	-0.216
ENSG00000120885	E026	39.3329566	0.0011408571	0.99177252	0.9976121	8	27610476	27610600	125	-	1.474	1.474	0.000
ENSG00000120885	E027	0.0000000				8	27610601	27611074	474	-
ENSG00000120885	E028	0.0000000				8	27611075	27611109	35	-
ENSG00000120885	E029	0.0000000				8	27611110	27611145	36	-
ENSG00000120885	E030	0.0000000				8	27611146	27611431	286	-
ENSG00000120885	E031	0.0000000				8	27611601	27611751	151	-
ENSG00000120885	E032	0.2027342	0.0376791381	1.00000000		8	27611830	27611966	137	-	0.000	0.057	8.557
ENSG00000120885	E033	0.0000000				8	27613578	27613683	106	-
ENSG00000120885	E034	0.0000000				8	27613684	27614172	489	-
ENSG00000120885	E035	0.1723744	0.0358441617	1.00000000		8	27614173	27614370	198	-	0.000	0.057	8.555
ENSG00000120885	E036	18.7277825	0.0039505597	0.01102405	0.0624685	8	27614655	27614700	46	-	0.883	1.199	1.158

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000120885

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3