ENSG00000120705

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360541 ENSG00000120705 HEK293_OSMI2_6hA HEK293_TMG_6hB ETF1 protein_coding protein_coding 76.41421 19.21846 132.0084 3.812913 6.08453 2.779424 54.20259 16.7236061 84.78646 3.7413953 3.933155 2.341256 0.7890833 0.85823333 0.6423000 -0.2159333 0.006061609 0.006061609 FALSE TRUE
ENST00000503014 ENSG00000120705 HEK293_OSMI2_6hA HEK293_TMG_6hB ETF1 protein_coding protein_coding 76.41421 19.21846 132.0084 3.812913 6.08453 2.779424 11.29271 0.3864794 29.55881 0.3864794 1.775778 6.220686 0.0900750 0.01703333 0.2237333 0.2067000 0.062514629 0.006061609 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000120705 E001 561.2303481 1.838064824 0.4225094390 0.645499793 5 138506095 138506872 778 - 2.544 2.880 1.118
ENSG00000120705 E002 1157.2624063 2.082900747 0.5084698259 0.706826858 5 138506873 138507989 1117 - 2.880 3.139 0.861
ENSG00000120705 E003 643.4198792 1.896567262 0.5009563069 0.701476127 5 138507990 138508387 398 - 2.626 2.882 0.851
ENSG00000120705 E004 561.9163773 0.006842348 0.1976561795 0.426659278 5 138508669 138508816 148 - 2.600 2.721 0.400
ENSG00000120705 E005 377.0360716 0.003741460 0.3440564980 0.581661761 5 138510565 138510629 65 - 2.443 2.486 0.146
ENSG00000120705 E006 349.2613074 0.012898030 0.6332855579 0.792525135 5 138511045 138511103 59 - 2.405 2.464 0.197
ENSG00000120705 E007 590.0115594 0.026886940 0.2798863977 0.519966172 5 138511104 138511200 97 - 2.641 2.647 0.019
ENSG00000120705 E008 16.3173616 0.239269788 0.7189354191 0.847528714 5 138511201 138511474 274 - 1.076 1.273 0.701
ENSG00000120705 E009 447.8053626 0.026828972 0.2403478920 0.476965723 5 138511475 138511524 50 - 2.525 2.512 -0.042
ENSG00000120705 E010 447.6275246 0.023694759 0.1055509428 0.291586325 5 138511525 138511604 80 - 2.529 2.490 -0.130
ENSG00000120705 E011 7.4116664 0.015742485 0.3507759468 0.587943265 5 138512699 138512763 65 - 0.825 0.733 -0.365
ENSG00000120705 E012 234.5820647 0.025886627 0.1409101886 0.348899838 5 138512764 138512771 8 - 2.248 2.220 -0.091
ENSG00000120705 E013 701.7900125 0.017457629 0.0402213436 0.155263547 5 138512772 138512954 183 - 2.725 2.683 -0.140
ENSG00000120705 E014 449.2038316 0.014956384 0.0111116411 0.062834351 5 138513568 138513650 83 - 2.537 2.459 -0.257
ENSG00000120705 E015 383.4202975 0.013050330 0.0027076472 0.021613197 5 138513651 138513706 56 - 2.472 2.365 -0.356
ENSG00000120705 E016 649.2792991 0.014324890 0.0009472263 0.009480804 5 138517561 138517700 140 - 2.702 2.582 -0.399
ENSG00000120705 E017 653.4575435 0.018053141 0.0054467400 0.036950925 5 138518692 138518867 176 - 2.702 2.601 -0.338
ENSG00000120705 E018 9.5876798 0.084922783 0.9366841958 0.970544152 5 138529555 138529678 124 - 0.902 0.978 0.285
ENSG00000120705 E019 0.5117739 0.029798953 0.5124717653   5 138541519 138541711 193 - 0.108 0.239 1.373
ENSG00000120705 E020 4.4706810 0.124658009 0.0596003244 0.201856844 5 138542634 138542704 71 - 0.532 0.957 1.746
ENSG00000120705 E021 11.4509269 0.072695383 0.6250473844 0.787350412 5 138542705 138542832 128 - 0.946 1.087 0.520
ENSG00000120705 E022 318.8743226 0.016118848 0.0866201363 0.257617695 5 138542833 138542936 104 - 2.381 2.348 -0.112
ENSG00000120705 E023 156.3306420 0.013995779 0.8214599398 0.908812973 5 138543097 138543267 171 - 2.058 2.117 0.196