ENSG00000107938

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337623 ENSG00000107938 HEK293_OSMI2_6hA HEK293_TMG_6hB EDRF1 protein_coding protein_coding 21.21214 9.405522 35.10617 0.254115 0.3530361 1.899022 2.040810 0.2288278 3.837955 0.2288278 1.4625448 4.01004927 0.0810250 0.02393333 0.10866667 0.084733333 0.347611763 0.003152143 FALSE TRUE
ENST00000356792 ENSG00000107938 HEK293_OSMI2_6hA HEK293_TMG_6hB EDRF1 protein_coding protein_coding 21.21214 9.405522 35.10617 0.254115 0.3530361 1.899022 8.568926 2.7839041 17.293369 1.0293514 1.2877340 2.63069851 0.3368125 0.30160000 0.49336667 0.191766667 0.617021542 0.003152143 FALSE TRUE
ENST00000368812 ENSG00000107938 HEK293_OSMI2_6hA HEK293_TMG_6hB EDRF1 protein_coding retained_intron 21.21214 9.405522 35.10617 0.254115 0.3530361 1.899022 3.286112 2.8054128 2.638869 0.4448317 0.7128673 -0.08796972 0.2364833 0.29613333 0.07480000 -0.221333333 0.003152143 0.003152143 FALSE TRUE
ENST00000368813 ENSG00000107938 HEK293_OSMI2_6hA HEK293_TMG_6hB EDRF1 protein_coding protein_coding 21.21214 9.405522 35.10617 0.254115 0.3530361 1.899022 1.276620 0.8284607 2.120712 0.4160244 0.3195374 1.34552033 0.0663000 0.08576667 0.06056667 -0.025200000 1.000000000 0.003152143 FALSE TRUE
ENST00000525091 ENSG00000107938 HEK293_OSMI2_6hA HEK293_TMG_6hB EDRF1 protein_coding retained_intron 21.21214 9.405522 35.10617 0.254115 0.3530361 1.899022 1.528369 0.7370843 2.483619 0.1740223 0.2218713 1.73889795 0.0700000 0.07783333 0.07066667 -0.007166667 0.958609391 0.003152143 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000107938 E001 0.0000000       10 125719515 125719575 61 +      
ENSG00000107938 E002 0.6434498 0.0195277720 3.966060e-01   10 125719576 125719665 90 + 0.213 0.001 -8.036
ENSG00000107938 E003 1.4896339 0.0122399284 4.509008e-01 0.6662952889 10 125719666 125719697 32 + 0.355 0.220 -0.939
ENSG00000107938 E004 1.9528871 0.0101244419 2.458563e-01 0.4834148008 10 125719698 125719701 4 + 0.437 0.220 -1.398
ENSG00000107938 E005 1.9528871 0.0101244419 2.458563e-01 0.4834148008 10 125719702 125719702 1 + 0.437 0.220 -1.398
ENSG00000107938 E006 2.2735056 0.0094001629 1.628243e-01 0.3809611916 10 125719703 125719708 6 + 0.485 0.220 -1.640
ENSG00000107938 E007 48.4949429 0.0302961259 6.246567e-02 0.2082879952 10 125719709 125719883 175 + 1.624 1.481 -0.487
ENSG00000107938 E008 40.0207239 0.0022735446 2.107894e-03 0.0177916903 10 125719884 125719915 32 + 1.551 1.356 -0.671
ENSG00000107938 E009 70.4424444 0.0137180664 2.650704e-02 0.1167917740 10 125721204 125721282 79 + 1.779 1.652 -0.430
ENSG00000107938 E010 103.5984930 0.0145938593 1.236929e-03 0.0116946346 10 125721283 125721412 130 + 1.955 1.757 -0.667
ENSG00000107938 E011 70.3730373 0.0152789430 4.313854e-02 0.1629139846 10 125723068 125723134 67 + 1.778 1.658 -0.407
ENSG00000107938 E012 94.2903092 0.0005505905 2.929711e-03 0.0229796439 10 125723811 125723936 126 + 1.903 1.803 -0.336
ENSG00000107938 E013 79.7615569 0.0097271734 3.497858e-01 0.5870732650 10 125725318 125725442 125 + 1.820 1.791 -0.098
ENSG00000107938 E014 54.0432281 0.9222543319 6.026677e-01 0.7719977966 10 125725682 125725765 84 + 1.635 1.679 0.149
ENSG00000107938 E015 52.1065824 0.9125684239 6.375548e-01 0.7954469655 10 125725766 125725838 73 + 1.626 1.636 0.034
ENSG00000107938 E016 54.9285421 0.0142038422 5.623172e-01 0.7449298793 10 125729003 125729104 102 + 1.658 1.649 -0.032
ENSG00000107938 E017 95.7904978 0.0010608658 2.906098e-05 0.0005249679 10 125729358 125729479 122 + 1.922 1.755 -0.563
ENSG00000107938 E018 0.4043710 0.0437574142 9.416196e-02   10 125730272 125730287 16 + 0.064 0.364 3.053
ENSG00000107938 E019 94.7653138 0.0065102995 1.640620e-03 0.0146032251 10 125730288 125730399 112 + 1.911 1.764 -0.496
ENSG00000107938 E020 4.4253138 0.1746061945 3.104065e-01 0.5509135008 10 125731865 125731925 61 + 0.685 0.477 -0.941
ENSG00000107938 E021 120.9264089 0.0187690428 5.604526e-02 0.1937649454 10 125733404 125733551 148 + 2.007 1.907 -0.333
ENSG00000107938 E022 134.8163209 0.0188147592 1.216210e-01 0.3184206141 10 125733635 125733743 109 + 2.048 1.973 -0.252
ENSG00000107938 E023 115.8164373 0.0182371337 1.186609e-01 0.3136592311 10 125734072 125734183 112 + 1.983 1.904 -0.265
ENSG00000107938 E024 156.4784979 0.0211699129 1.986218e-01 0.4279364455 10 125735644 125735886 243 + 2.108 2.056 -0.174
ENSG00000107938 E025 61.3604382 0.0554509284 3.768080e-01 0.6096914707 10 125735887 125735904 18 + 1.705 1.669 -0.121
ENSG00000107938 E026 54.8170609 0.0487214447 5.235302e-01 0.7174759712 10 125737918 125737922 5 + 1.651 1.645 -0.019
ENSG00000107938 E027 76.7073393 0.0345998107 6.138865e-01 0.7794720958 10 125737923 125737989 67 + 1.791 1.802 0.038
ENSG00000107938 E028 110.1993431 0.0104775511 7.816010e-01 0.8855920865 10 125738295 125738445 151 + 1.942 1.974 0.107
ENSG00000107938 E029 155.8330765 0.0085059442 2.911368e-01 0.5317114733 10 125740463 125740651 189 + 2.100 2.087 -0.042
ENSG00000107938 E030 156.5415544 0.0098100207 3.975859e-01 0.6264425228 10 125741001 125741201 201 + 2.100 2.095 -0.018
ENSG00000107938 E031 19.0645472 0.0708126749 2.264832e-01 0.4611923191 10 125741202 125741665 464 + 1.150 1.378 0.802
ENSG00000107938 E032 15.2789607 0.0449974441 1.643271e-01 0.3831613423 10 125742220 125742345 126 + 1.065 1.299 0.833
ENSG00000107938 E033 128.8629329 0.0043738069 5.613676e-01 0.7442722702 10 125743058 125743276 219 + 2.018 2.026 0.027
ENSG00000107938 E034 54.4659507 0.9302864653 5.610320e-01 0.7440366795 10 125745707 125745771 65 + 1.629 1.713 0.283
ENSG00000107938 E035 85.7991391 0.1355273735 4.445467e-01 0.6618122507 10 125745772 125745930 159 + 1.820 1.920 0.337
ENSG00000107938 E036 14.7903869 0.1665397499 5.821199e-01 0.7584459082 10 125746701 125747535 835 + 1.056 1.256 0.715
ENSG00000107938 E037 99.6034210 0.0140362123 1.384043e-01 0.3451327321 10 125747536 125747694 159 + 1.877 2.018 0.473
ENSG00000107938 E038 86.5091961 0.0186327352 1.413428e-01 0.3494838808 10 125747863 125747952 90 + 1.814 1.966 0.509
ENSG00000107938 E039 76.4768342 0.0577809638 2.291723e-01 0.4641581226 10 125747953 125748012 60 + 1.759 1.914 0.525
ENSG00000107938 E040 49.8200983 0.0932118297 2.308919e-01 0.4661887069 10 125748013 125749096 1084 + 1.547 1.799 0.858
ENSG00000107938 E041 5.7993783 0.0061311445 2.081119e-02 0.0987093381 10 125749273 125749296 24 + 0.666 1.009 1.344
ENSG00000107938 E042 9.5922397 0.0697703271 2.292917e-02 0.1057065476 10 125749297 125749411 115 + 0.838 1.210 1.369
ENSG00000107938 E043 99.1477496 1.3219161609 4.264651e-01 0.6483717503 10 125749412 125749565 154 + 1.843 2.086 0.816
ENSG00000107938 E044 1.0317300 0.4380242102 1.787772e-01   10 125749566 125749813 248 + 0.169 0.485 2.109
ENSG00000107938 E045 79.3033013 0.3024538648 2.177615e-01 0.4507449850 10 125752799 125752914 116 + 1.753 1.977 0.754
ENSG00000107938 E046 51.2307233 0.8298366815 2.325659e-01 0.4681336614 10 125753694 125753778 85 + 1.524 1.879 1.203
ENSG00000107938 E047 63.0374143 0.1481650475 6.330191e-02 0.2101430391 10 125753779 125753845 67 + 1.631 1.935 1.026
ENSG00000107938 E048 2.2434826 0.2353833303 5.846175e-02 0.1993316479 10 125761228 125761314 87 + 0.289 0.798 2.481
ENSG00000107938 E049 149.6735065 0.0037636552 4.196344e-04 0.0049221974 10 125763301 125763524 224 + 2.039 2.224 0.622
ENSG00000107938 E050 305.2760145 0.0079862477 2.834820e-01 0.5239435838 10 125763525 125764040 516 + 2.368 2.460 0.306
ENSG00000107938 E051 44.7652607 0.0206244371 3.412072e-02 0.1391833785 10 125764041 125764143 103 + 1.505 1.740 0.803