ENSG00000107929

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316157 ENSG00000107929 HEK293_OSMI2_6hA HEK293_TMG_6hB LARP4B protein_coding protein_coding 26.79143 25.93073 30.03523 5.21926 0.9637615 0.2119171 12.807898 14.6854331 12.676565 3.1815897 0.2230305 -0.2120663 0.4791208 0.5614667 0.42250000 -0.138966667 0.002371615 0.002371615 FALSE TRUE
ENST00000690211 ENSG00000107929 HEK293_OSMI2_6hA HEK293_TMG_6hB LARP4B protein_coding protein_coding 26.79143 25.93073 30.03523 5.21926 0.9637615 0.2119171 4.929211 4.1668570 5.785949 0.5472308 0.3526045 0.4726272 0.1826083 0.1681000 0.19263333 0.024533333 0.826640550 0.002371615 FALSE FALSE
ENST00000690516 ENSG00000107929 HEK293_OSMI2_6hA HEK293_TMG_6hB LARP4B protein_coding nonsense_mediated_decay 26.79143 25.93073 30.03523 5.21926 0.9637615 0.2119171 2.605235 2.7841093 2.803967 1.4228394 0.3311241 0.0102168 0.1061875 0.0893000 0.09283333 0.003533333 0.930774814 0.002371615 FALSE TRUE
MSTRG.3471.11 ENSG00000107929 HEK293_OSMI2_6hA HEK293_TMG_6hB LARP4B protein_coding   26.79143 25.93073 30.03523 5.21926 0.9637615 0.2119171 2.954913 0.4335853 5.895216 0.4335853 0.4150002 3.7347064 0.0983500 0.0280000 0.19583333 0.167833333 0.134767842 0.002371615 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000107929 E001 2.1187764 0.0106768433 3.581039e-01 5.942998e-01 10 806933 806951 19 - 0.420 0.587 0.809
ENSG00000107929 E002 19.5608944 0.0023828839 4.335811e-02 1.634742e-01 10 806952 807879 928 - 1.214 1.391 0.619
ENSG00000107929 E003 10.5946539 0.0027803812 3.202203e-02 1.332862e-01 10 807880 808272 393 - 0.930 1.167 0.867
ENSG00000107929 E004 2.3758130 0.0090199277 4.864277e-03 3.389267e-02 10 809497 809548 52 - 0.218 0.711 2.664
ENSG00000107929 E005 895.9079199 0.0033792189 3.122114e-10 1.992510e-08 10 809549 811805 2257 - 2.842 3.037 0.646
ENSG00000107929 E006 23.3160764 0.0014234177 2.451755e-03 2.001752e-02 10 811806 811821 16 - 1.247 1.486 0.832
ENSG00000107929 E007 573.1052360 0.0001447665 3.653010e-08 1.506472e-06 10 811822 812505 684 - 2.706 2.806 0.334
ENSG00000107929 E008 362.4797251 0.0006822283 4.995320e-03 3.460413e-02 10 812506 812920 415 - 2.520 2.597 0.257
ENSG00000107929 E009 299.2762638 0.0003214333 5.524986e-01 7.380395e-01 10 812921 813213 293 - 2.478 2.483 0.018
ENSG00000107929 E010 8.8597358 0.0156745627 6.804418e-01 8.230214e-01 10 813214 813256 43 - 1.020 0.992 -0.102
ENSG00000107929 E011 5.1246409 0.1658093074 5.154013e-01 7.119084e-01 10 814018 814441 424 - 0.853 0.716 -0.542
ENSG00000107929 E012 4.3317320 0.0619026067 1.878410e-01 4.142014e-01 10 814442 814636 195 - 0.817 0.593 -0.933
ENSG00000107929 E013 23.1501459 0.0032316783 3.948398e-02 1.534180e-01 10 814637 814741 105 - 1.292 1.463 0.590
ENSG00000107929 E014 211.7691643 0.0004018250 1.494965e-01 3.615434e-01 10 814742 814850 109 - 2.339 2.320 -0.064
ENSG00000107929 E015 209.7418320 0.0003380616 3.938166e-02 1.531761e-01 10 814946 815070 125 - 2.341 2.306 -0.114
ENSG00000107929 E016 7.3217385 0.3213822191 8.647084e-01 9.329750e-01 10 815071 815715 645 - 0.903 0.935 0.122
ENSG00000107929 E017 253.1545719 0.0002370971 7.884250e-01 8.896111e-01 10 817725 817889 165 - 2.400 2.412 0.041
ENSG00000107929 E018 48.0640610 0.1601472011 7.365194e-01 8.582796e-01 10 817890 820799 2910 - 1.621 1.747 0.428
ENSG00000107929 E019 139.6372705 0.0003344556 8.835438e-02 2.607148e-01 10 820800 820845 46 - 2.111 2.181 0.235
ENSG00000107929 E020 3.6344187 0.2855231443 1.866451e-01 4.126252e-01 10 820846 820930 85 - 0.425 0.802 1.686
ENSG00000107929 E021 266.2024722 0.0002673429 2.570961e-01 4.958919e-01 10 825065 825316 252 - 2.431 2.425 -0.020
ENSG00000107929 E022 155.4633933 0.0003230479 2.554932e-01 4.941362e-01 10 825764 825870 107 - 2.204 2.190 -0.047
ENSG00000107929 E023 2.2472391 0.3647899161 4.983461e-01 6.996927e-01 10 825871 827283 1413 - 0.414 0.592 0.868
ENSG00000107929 E024 207.4389502 0.0072461932 2.232099e-01 4.572021e-01 10 829385 829594 210 - 2.335 2.304 -0.104
ENSG00000107929 E025 111.5125844 0.0037847157 2.693409e-01 5.091374e-01 10 829681 829734 54 - 2.065 2.034 -0.102
ENSG00000107929 E026 183.2520174 0.0032925933 3.295810e-03 2.516996e-02 10 830867 830977 111 - 2.308 2.214 -0.316
ENSG00000107929 E027 182.6766418 0.0029313667 6.643244e-04 7.132677e-03 10 836403 836506 104 - 2.313 2.205 -0.359
ENSG00000107929 E028 222.3465537 0.0002789280 1.027245e-09 5.986609e-08 10 842932 843068 137 - 2.409 2.279 -0.434
ENSG00000107929 E029 144.6937608 0.0003078588 3.515035e-05 6.174243e-04 10 844977 845055 79 - 2.215 2.110 -0.350
ENSG00000107929 E030 106.1462191 0.0003860107 2.120541e-04 2.808146e-03 10 863743 863778 36 - 2.083 1.973 -0.369
ENSG00000107929 E031 154.3304780 0.0007176902 4.265976e-06 1.003408e-04 10 863779 863883 105 - 2.253 2.132 -0.403
ENSG00000107929 E032 93.9270862 0.0088215706 1.522873e-02 7.894589e-02 10 864123 864153 31 - 2.036 1.923 -0.381
ENSG00000107929 E033 123.1620572 0.0093335709 4.115860e-02 1.577485e-01 10 864154 864240 87 - 2.141 2.050 -0.308
ENSG00000107929 E034 85.3321402 0.0015414194 4.319295e-03 3.093712e-02 10 864241 864269 29 - 1.987 1.886 -0.338
ENSG00000107929 E035 68.7951793 0.0008796695 8.697049e-04 8.847245e-03 10 864270 864270 1 - 1.909 1.782 -0.427
ENSG00000107929 E036 0.3393995 0.0246721969 1.879728e-01   10 870009 870012 4 - 0.218 0.000 -12.668
ENSG00000107929 E037 6.6904677 0.0043310552 4.693061e-03 3.296808e-02 10 870013 870083 71 - 1.020 0.684 -1.308
ENSG00000107929 E038 0.6294705 0.0271690775 2.856156e-01   10 870084 873205 3122 - 0.297 0.120 -1.624
ENSG00000107929 E039 97.7502166 0.0086369447 8.221407e-03 5.034923e-02 10 884447 884506 60 - 2.062 1.925 -0.457
ENSG00000107929 E040 92.6464223 0.0095152893 5.619710e-02 1.940852e-01 10 885641 885760 120 - 2.022 1.919 -0.345
ENSG00000107929 E041 0.1723744 0.0652265974 5.066361e-01   10 889442 889834 393 - 0.000 0.120 10.343
ENSG00000107929 E042 0.0000000       10 903208 903343 136 -      
ENSG00000107929 E043 0.0000000       10 903430 903515 86 -      
ENSG00000107929 E044 0.1723744 0.0652265974 5.066361e-01   10 924383 924433 51 - 0.000 0.120 10.343
ENSG00000107929 E045 39.1876634 0.0032882929 2.005427e-02 9.606443e-02 10 931428 931705 278 - 1.519 1.681 0.552
ENSG00000107929 E046 1.7008740 0.2021366151 3.389405e-01 5.770268e-01 10 931779 931834 56 - 0.522 0.346 -0.931