ENSG00000107890

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376087 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding protein_coding 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 1.1404228 0.5050106 1.72309397 0.26322393 0.10994631 1.75067577 0.28682083 0.25970000 0.34060000 0.08090000 8.758898e-01 9.633541e-07 FALSE TRUE
ENST00000436985 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding protein_coding 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.6804673 0.0000000 1.69440649 0.00000000 0.35588441 7.41312564 0.12117083 0.00000000 0.33373333 0.33373333 9.633541e-07 9.633541e-07 FALSE TRUE
ENST00000445828 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding protein_coding 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.1584373 0.1441500 0.14280597 0.14415001 0.08870532 -0.01263404 0.05963333 0.07986667 0.02826667 -0.05160000 9.827487e-01 9.633541e-07 FALSE TRUE
ENST00000675349 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding processed_transcript 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.2581388 0.0779905 0.36175042 0.04648222 0.04270193 2.07891477 0.06198333 0.03890000 0.07160000 0.03270000 7.239530e-01 9.633541e-07 FALSE TRUE
ENST00000675936 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding nonsense_mediated_decay 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.1936878 0.2801983 0.00000000 0.14172398 0.00000000 -4.85896713 0.09516667 0.14226667 0.00000000 -0.14226667 1.752387e-01 9.633541e-07 TRUE TRUE
ENST00000676280 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding protein_coding 3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.1414066 0.1679718 0.01948297 0.16797175 0.01948297 -2.59369437 0.09231667 0.08833333 0.00390000 -0.08443333 9.022709e-01 9.633541e-07 FALSE TRUE
MSTRG.3688.4 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding   3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.1581755 0.2606225 0.00000000 0.10200034 0.00000000 -4.75820970 0.04575417 0.13936667 0.00000000 -0.13936667 1.229380e-03 9.633541e-07 TRUE TRUE
MSTRG.3688.7 ENSG00000107890 HEK293_OSMI2_6hA HEK293_TMG_6hB ANKRD26 protein_coding   3.552748 1.921321 5.068602 0.07348981 0.06638405 1.394843 0.3895749 0.2101732 0.19949805 0.07592873 0.19949805 -0.07170200 0.10121250 0.10780000 0.03980000 -0.06800000 4.776968e-01 9.633541e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000107890 E001 0.1723744 0.0304502769 0.1682126105   10 26973793 26973871 79 - 0.000 0.187 11.285
ENSG00000107890 E002 5.9061185 0.0647608526 0.0002299544 0.003000733 10 26973872 26976007 2136 - 0.520 1.149 2.504
ENSG00000107890 E003 1.5773305 0.0121989077 0.8206393978 0.908442262 10 26976008 26976042 35 - 0.372 0.417 0.253
ENSG00000107890 E004 1.4644356 0.0121777957 0.2635978680 0.502875606 10 26980576 26980618 43 - 0.294 0.499 1.153
ENSG00000107890 E005 2.9189423 0.0523643853 0.0062353435 0.040886995 10 26980619 26980726 108 - 0.372 0.840 2.126
ENSG00000107890 E006 2.3469986 0.2002992996 0.0278761523 0.120936186 10 26980727 26980839 113 - 0.297 0.769 2.311
ENSG00000107890 E007 0.6368449 0.0198567079 0.0024005862   10 26982054 26982162 109 - 0.000 0.498 16.090
ENSG00000107890 E008 3.5808114 0.0294430925 0.0018395342 0.015983383 10 26982693 26982813 121 - 0.438 0.928 2.104
ENSG00000107890 E009 0.4231520 0.0679635903 0.1656494427   10 26991914 26992005 92 - 0.077 0.315 2.459
ENSG00000107890 E010 1.7851561 0.2223588116 0.0243706315 0.110233487 10 26992263 26992404 142 - 0.200 0.693 2.747
ENSG00000107890 E011 1.5456153 0.0130224150 0.3796521267 0.611912891 10 26995041 26995147 107 - 0.335 0.498 0.884
ENSG00000107890 E012 2.5517374 0.0093693905 0.7049010753 0.838650377 10 27004116 27004184 69 - 0.495 0.567 0.337
ENSG00000107890 E013 35.2813940 0.0040991395 0.0038943179 0.028557939 10 27004185 27005266 1082 - 1.445 1.644 0.680
ENSG00000107890 E014 6.4349764 0.0264776226 0.6685559448 0.815268284 10 27005267 27005314 48 - 0.856 0.801 -0.213
ENSG00000107890 E015 14.1954171 0.0052587857 0.2311016786 0.466463587 10 27005315 27005616 302 - 1.107 1.232 0.446
ENSG00000107890 E016 6.9172773 0.0051578613 0.1009851298 0.283572229 10 27005617 27005622 6 - 0.794 1.005 0.804
ENSG00000107890 E017 15.8570296 0.0082658817 0.0461095622 0.170275603 10 27005623 27005723 101 - 1.121 1.318 0.696
ENSG00000107890 E018 14.4784555 0.0179533204 0.2214086302 0.455165091 10 27006917 27006962 46 - 1.103 1.243 0.499
ENSG00000107890 E019 30.5991752 0.0195939948 0.1656672487 0.384708389 10 27012882 27013110 229 - 1.414 1.543 0.445
ENSG00000107890 E020 28.6422074 0.0014962332 0.1067934898 0.293666966 10 27014494 27014711 218 - 1.388 1.507 0.410
ENSG00000107890 E021 36.8557214 0.0055375133 0.0337333863 0.138160931 10 27017502 27017792 291 - 1.484 1.632 0.505
ENSG00000107890 E022 22.0747723 0.0220946988 0.0072399128 0.045776228 10 27022558 27022687 130 - 1.224 1.486 0.913
ENSG00000107890 E023 22.0859546 0.0032518277 0.0423951972 0.160970909 10 27024447 27024559 113 - 1.261 1.428 0.583
ENSG00000107890 E024 24.4271336 0.0017137461 0.0034762461 0.026201611 10 27028852 27028945 94 - 1.287 1.508 0.762
ENSG00000107890 E025 20.8138877 0.0019393597 0.0865116860 0.257426048 10 27029286 27029356 71 - 1.247 1.392 0.505
ENSG00000107890 E026 0.4820342 0.0213279875 0.4035910077   10 27030393 27030600 208 - 0.199 0.000 -14.413
ENSG00000107890 E027 27.1508037 0.0014467241 0.3461789666 0.583721498 10 27033225 27033377 153 - 1.378 1.453 0.262
ENSG00000107890 E028 26.6005494 0.0013483385 0.4722168785 0.681718610 10 27034796 27034906 111 - 1.377 1.437 0.205
ENSG00000107890 E029 81.9236123 0.0008135289 0.4921027986 0.695418176 10 27034907 27035672 766 - 1.871 1.848 -0.077
ENSG00000107890 E030 10.0378045 0.0399802439 0.2063871680 0.437448991 10 27035673 27035677 5 - 1.033 0.841 -0.723
ENSG00000107890 E031 16.2142306 0.0068533599 0.4924302279 0.695640650 10 27035678 27035752 75 - 1.203 1.142 -0.215
ENSG00000107890 E032 20.1545419 0.0176840016 0.9547554756 0.979288559 10 27037186 27037323 138 - 1.275 1.294 0.070
ENSG00000107890 E033 0.0000000       10 27037664 27037782 119 -      
ENSG00000107890 E034 20.1556572 0.0669126849 0.7915377789 0.891340029 10 27037871 27037995 125 - 1.279 1.286 0.024
ENSG00000107890 E035 16.2032719 0.0051316227 0.3619402418 0.597306037 10 27037996 27038054 59 - 1.208 1.125 -0.294
ENSG00000107890 E036 10.9472947 0.0275156351 0.5036509091 0.703343626 10 27039965 27039987 23 - 1.046 0.959 -0.322
ENSG00000107890 E037 20.0397771 0.0220176461 0.7120954483 0.843142122 10 27039988 27040097 110 - 1.279 1.247 -0.112
ENSG00000107890 E038 15.2261831 0.0164583430 0.9325582273 0.968439555 10 27040098 27040178 81 - 1.160 1.158 -0.007
ENSG00000107890 E039 16.0207307 0.0021570351 0.1174329215 0.311538273 10 27043426 27043567 142 - 1.217 1.070 -0.528
ENSG00000107890 E040 10.5973211 0.0031921388 0.0929644038 0.269254936 10 27044157 27044190 34 - 1.066 0.872 -0.723
ENSG00000107890 E041 0.8455639 0.0953997479 0.5670629113   10 27046111 27046352 242 - 0.200 0.318 0.889
ENSG00000107890 E042 22.3805652 0.0015577083 0.1480078095 0.359471953 10 27046353 27046520 168 - 1.348 1.234 -0.401
ENSG00000107890 E043 6.6763366 0.0043631323 0.1270138764 0.327041130 10 27046521 27046523 3 - 0.891 0.678 -0.848
ENSG00000107890 E044 23.5364115 0.0020905408 0.2778947893 0.517960410 10 27048801 27048979 179 - 1.367 1.285 -0.286
ENSG00000107890 E045 7.6851649 0.0151381737 0.1418176058 0.350183517 10 27051059 27052425 1367 - 0.932 0.726 -0.806
ENSG00000107890 E046 18.2886970 0.0018079493 0.0570264076 0.196115826 10 27053320 27053390 71 - 1.279 1.108 -0.607
ENSG00000107890 E047 14.7635210 0.0021487284 0.1096711111 0.298491524 10 27060345 27060414 70 - 1.186 1.028 -0.566
ENSG00000107890 E048 8.3754024 0.0038900106 0.9903415933 0.996901975 10 27060415 27060417 3 - 0.922 0.931 0.033
ENSG00000107890 E049 9.4124816 0.0046453010 0.3358841223 0.574308045 10 27060512 27060540 29 - 0.932 1.050 0.438
ENSG00000107890 E050 0.1723744 0.0304502769 0.1682126105   10 27060818 27060881 64 - 0.000 0.187 14.168
ENSG00000107890 E051 14.2539421 0.0043300002 0.8005431002 0.896635939 10 27061144 27061229 86 - 1.145 1.126 -0.067
ENSG00000107890 E052 8.1189021 0.0041589368 0.9922322268 0.997813226 10 27061230 27061242 13 - 0.922 0.930 0.032
ENSG00000107890 E053 0.6300180 0.2712446812 0.4065220740   10 27063036 27063987 952 - 0.140 0.320 1.515
ENSG00000107890 E054 12.0975309 0.0026299249 0.3745898635 0.607808825 10 27063988 27064081 94 - 1.094 1.006 -0.323
ENSG00000107890 E055 0.0000000       10 27066241 27066486 246 -      
ENSG00000107890 E056 11.1565182 0.0029631023 0.1679785848 0.387902843 10 27066487 27066548 62 - 1.080 0.930 -0.553
ENSG00000107890 E057 17.1835873 0.0019744652 0.5189159490 0.714289401 10 27067157 27067286 130 - 1.227 1.175 -0.185
ENSG00000107890 E058 0.0000000       10 27077023 27077337 315 -      
ENSG00000107890 E059 25.5280725 0.0084347116 0.1151244825 0.307658662 10 27077338 27077540 203 - 1.407 1.273 -0.468
ENSG00000107890 E060 13.4575364 0.0167071216 0.0158787044 0.081348732 10 27077633 27077693 61 - 1.174 0.873 -1.108
ENSG00000107890 E061 14.4200120 0.0032330341 0.0009910113 0.009843052 10 27079089 27079161 73 - 1.212 0.840 -1.370
ENSG00000107890 E062 0.9888187 0.0155920584 0.5758184371   10 27080032 27080153 122 - 0.294 0.187 -0.847
ENSG00000107890 E063 0.8040577 0.0177178284 0.5306233022   10 27080649 27080771 123 - 0.199 0.317 0.886
ENSG00000107890 E064 9.9303766 0.0031906394 0.0001828371 0.002481019 10 27082803 27082833 31 - 1.087 0.567 -2.063
ENSG00000107890 E065 11.2717664 0.0027159792 0.0004567946 0.005285428 10 27086539 27086609 71 - 1.127 0.678 -1.719
ENSG00000107890 E066 13.7836674 0.0339693284 0.0026705491 0.021403063 10 27092406 27092512 107 - 1.208 0.766 -1.646
ENSG00000107890 E067 18.9724610 0.0025993071 0.0021430355 0.018030951 10 27093349 27093522 174 - 1.321 1.028 -1.044
ENSG00000107890 E068 14.6841860 0.0027124764 0.0005285361 0.005935563 10 27093685 27093799 115 - 1.227 0.839 -1.425
ENSG00000107890 E069 0.0000000       10 27098180 27098326 147 -      
ENSG00000107890 E070 16.9147601 0.0245802322 0.0023340600 0.019277165 10 27100085 27100494 410 - 1.281 0.875 -1.475