ENSG00000107560

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355624 ENSG00000107560 HEK293_OSMI2_6hA HEK293_TMG_6hB RAB11FIP2 protein_coding protein_coding 6.161464 1.534235 11.24765 0.4153272 0.67505 2.865942 3.6607115 1.1776183 6.5363337 0.4806219 0.5567700 2.4626160 0.67837083 0.6892333 0.58063333 -0.10860000 8.071714e-01 1.059401e-05 FALSE TRUE
ENST00000369199 ENSG00000107560 HEK293_OSMI2_6hA HEK293_TMG_6hB RAB11FIP2 protein_coding protein_coding 6.161464 1.534235 11.24765 0.4153272 0.67505 2.865942 0.4358151 0.3130682 0.4221661 0.1233220 0.2911521 0.4197472 0.11472917 0.2500667 0.03526667 -0.21480000 3.390642e-01 1.059401e-05 FALSE TRUE
ENST00000483413 ENSG00000107560 HEK293_OSMI2_6hA HEK293_TMG_6hB RAB11FIP2 protein_coding retained_intron 6.161464 1.534235 11.24765 0.4153272 0.67505 2.865942 1.2925331 0.0000000 2.9734113 0.0000000 0.7396509 8.2208191 0.11525833 0.0000000 0.25920000 0.25920000 1.059401e-05 1.059401e-05 FALSE TRUE
MSTRG.4703.3 ENSG00000107560 HEK293_OSMI2_6hA HEK293_TMG_6hB RAB11FIP2 protein_coding   6.161464 1.534235 11.24765 0.4153272 0.67505 2.865942 0.6145844 0.0435481 0.9852844 0.0435481 0.3902881 4.2162015 0.07592083 0.0607000 0.09196667 0.03126667 7.527595e-01 1.059401e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000107560 E001 0.4880035 0.053694312 6.715042e-01   10 118004916 118004947 32 - 0.126 0.209 0.869
ENSG00000107560 E002 64.8123195 0.130625517 7.342795e-02 2.316507e-01 10 118004948 118005462 515 - 1.667 1.927 0.878
ENSG00000107560 E003 49.0545582 0.033652090 8.524680e-03 5.171788e-02 10 118005463 118005628 166 - 1.543 1.824 0.953
ENSG00000107560 E004 37.4239350 0.002164808 7.646033e-04 7.983229e-03 10 118005629 118005755 127 - 1.444 1.695 0.857
ENSG00000107560 E005 15.0719027 0.036947623 3.851896e-02 1.509219e-01 10 118005756 118005771 16 - 1.047 1.336 1.026
ENSG00000107560 E006 25.1394335 0.015951039 1.027329e-01 2.866599e-01 10 118005772 118005838 67 - 1.294 1.479 0.642
ENSG00000107560 E007 258.3851068 1.004294653 4.224280e-01 6.454215e-01 10 118005839 118009075 3237 - 2.304 2.423 0.397
ENSG00000107560 E008 19.2935951 0.002340697 1.703798e-02 8.560983e-02 10 118009076 118009081 6 - 1.280 1.081 -0.708
ENSG00000107560 E009 41.0925868 0.001599738 1.206489e-02 6.670451e-02 10 118009082 118009225 144 - 1.588 1.457 -0.451
ENSG00000107560 E010 24.8919536 0.158350592 2.107275e-01 4.426707e-01 10 118015065 118015110 46 - 1.354 1.272 -0.288
ENSG00000107560 E011 4.9573285 0.399976307 9.428063e-01 9.736990e-01 10 118033982 118034041 60 - 0.658 0.852 0.784
ENSG00000107560 E012 0.0000000       10 118038924 118038971 48 -      
ENSG00000107560 E013 86.5217765 0.436651602 1.264139e-01 3.261232e-01 10 118038972 118039440 469 - 1.902 1.677 -0.759
ENSG00000107560 E014 72.0557102 0.001073831 6.175055e-10 3.738561e-08 10 118040123 118040565 443 - 1.850 1.549 -1.022
ENSG00000107560 E015 57.6118477 0.249135484 7.133258e-01 8.439046e-01 10 118045811 118046941 1131 - 1.699 1.652 -0.159