ENSG00000103723

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000542200 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding protein_coding 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.09269745 0.05699239 0.1376236 0.01118767 0.02599472 1.1398544 0.02899167 0.01136667 0.06820000 0.05683333 0.03179984 0.03179984 FALSE  
ENST00000559888 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding retained_intron 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.24985009 1.16324812 0.0000000 0.70701097 0.00000000 -6.8743643 0.05208333 0.19390000 0.00000000 -0.19390000 0.45104870 0.03179984 FALSE  
ENST00000659252 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding retained_intron 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.15943895 0.11695738 0.2174331 0.11695738 0.21743311 0.8410981 0.03887083 0.01886667 0.09326667 0.07440000 0.94930746 0.03179984    
ENST00000660624 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding protein_coding 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.98641323 1.12929034 0.4856829 0.22523563 0.04410583 -1.2006459 0.25961250 0.22620000 0.24173333 0.01553333 0.96013976 0.03179984 FALSE  
ENST00000664460 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding protein_coding 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.36617937 0.45873533 0.2763150 0.07927664 0.04629047 -0.7111703 0.09764583 0.09050000 0.13793333 0.04743333 0.68009474 0.03179984 FALSE  
ENST00000668990 ENSG00000103723 HEK293_OSMI2_6hA HEK293_TMG_6hB AP3B2 protein_coding protein_coding 3.85095 5.271615 2.011303 0.7910648 0.1864805 -1.385693 0.57089442 0.84492019 0.1653248 0.46208405 0.16532475 -2.2857600 0.14497917 0.17466667 0.09810000 -0.07656667 0.78247867 0.03179984 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000103723 E001 0.2852693 0.249431516 0.060961043   15 82659281 82659281 1 - 0.322 0.000 -12.230
ENSG00000103723 E002 0.2852693 0.249431516 0.060961043   15 82659282 82659284 3 - 0.322 0.000 -15.039
ENSG00000103723 E003 0.4576437 0.101563268 0.152183448   15 82659285 82659286 2 - 0.324 0.074 -2.568
ENSG00000103723 E004 0.6300180 0.301957975 0.372749233   15 82659287 82659291 5 - 0.321 0.139 -1.536
ENSG00000103723 E005 1.3504955 0.337849864 0.687649942   15 82659292 82659294 3 - 0.420 0.297 -0.734
ENSG00000103723 E006 1.3504955 0.337849864 0.687649942   15 82659295 82659299 5 - 0.420 0.297 -0.734
ENSG00000103723 E007 1.5228699 0.394024354 0.813616816 0.90442521 15 82659300 82659301 2 - 0.419 0.339 -0.458
ENSG00000103723 E008 3.4328521 0.132116020 0.939500616 0.97196020 15 82659302 82659311 10 - 0.577 0.592 0.069
ENSG00000103723 E009 3.4328521 0.132116020 0.939500616 0.97196020 15 82659312 82659317 6 - 0.577 0.592 0.069
ENSG00000103723 E010 6.4026436 0.011983237 0.355188639 0.59191508 15 82659318 82659347 30 - 0.691 0.833 0.574
ENSG00000103723 E011 7.1772513 0.024785330 0.411933773 0.63752115 15 82659348 82659366 19 - 0.738 0.871 0.524
ENSG00000103723 E012 16.1847247 0.002248194 0.675963171 0.82016871 15 82659367 82659494 128 - 1.141 1.181 0.144
ENSG00000103723 E013 11.8036502 0.003093745 0.343596648 0.58123815 15 82659495 82659512 18 - 0.972 1.079 0.393
ENSG00000103723 E014 13.0764978 0.003024736 0.903638240 0.95370964 15 82659513 82659531 19 - 1.085 1.099 0.050
ENSG00000103723 E015 12.0651645 0.003280205 0.607196081 0.77502751 15 82659532 82659551 20 - 1.104 1.051 -0.193
ENSG00000103723 E016 23.2703969 0.005843108 0.914333996 0.95926063 15 82659552 82659710 159 - 1.324 1.332 0.028
ENSG00000103723 E017 0.4873834 0.097261348 0.732925571   15 82659711 82659741 31 - 0.192 0.138 -0.570
ENSG00000103723 E018 19.0284588 0.008446000 0.367801579 0.60224432 15 82659845 82659954 110 - 1.175 1.262 0.310
ENSG00000103723 E019 11.5815738 0.003653210 0.586126697 0.76103589 15 82659955 82659983 29 - 0.997 1.058 0.224
ENSG00000103723 E020 3.3419601 0.699800298 0.285487570 0.52608351 15 82659984 82661824 1841 - 0.633 0.573 -0.267
ENSG00000103723 E021 18.0326933 0.002184144 0.403063071 0.63078266 15 82661825 82661922 98 - 1.158 1.236 0.276
ENSG00000103723 E022 14.6215814 0.002318476 0.716121268 0.84568591 15 82662168 82662252 85 - 1.105 1.142 0.134
ENSG00000103723 E023 4.5659615 0.140108224 0.790981300 0.89106274 15 82662253 82662693 441 - 0.691 0.694 0.011
ENSG00000103723 E024 21.7668327 0.002489629 0.490514823 0.69434496 15 82662694 82662922 229 - 1.249 1.309 0.210
ENSG00000103723 E025 0.9630002 0.130357166 0.698974235   15 82662923 82663126 204 - 0.192 0.287 0.752
ENSG00000103723 E026 15.9114093 0.003343318 0.167044968 0.38659606 15 82663127 82663233 107 - 1.065 1.206 0.507
ENSG00000103723 E027 1.5694852 0.112448439 0.315372164 0.55539813 15 82663234 82663251 18 - 0.192 0.427 1.587
ENSG00000103723 E028 1.6940039 0.984975845 1.000000000 1.00000000 15 82663252 82663295 44 - 0.189 0.441 1.694
ENSG00000103723 E029 2.3969331 0.906216793 0.573882325 0.75292530 15 82663296 82663559 264 - 0.434 0.498 0.327
ENSG00000103723 E030 13.4192661 0.029036096 0.830647724 0.91414556 15 82663560 82663620 61 - 1.064 1.112 0.172
ENSG00000103723 E031 1.7074357 0.692070394 0.489772803 0.69382709 15 82663621 82663800 180 - 0.433 0.373 -0.329
ENSG00000103723 E032 23.6427960 0.026423562 0.767230844 0.87694222 15 82663801 82663975 175 - 1.301 1.343 0.147
ENSG00000103723 E033 1.3077489 0.303584068 0.619132893   15 82663976 82664366 391 - 0.191 0.366 1.260
ENSG00000103723 E034 21.0684919 0.004006372 0.758389429 0.87160665 15 82664367 82664490 124 - 1.301 1.277 -0.085
ENSG00000103723 E035 1.5101233 0.022978956 0.570739672 0.75081057 15 82664491 82664555 65 - 0.428 0.326 -0.582
ENSG00000103723 E036 1.1597651 0.075237160 0.799896454   15 82664556 82664834 279 - 0.326 0.287 -0.261
ENSG00000103723 E037 17.0112651 0.002895805 0.739465097 0.86007740 15 82664835 82664943 109 - 1.174 1.207 0.115
ENSG00000103723 E038 0.0000000       15 82665247 82665303 57 -      
ENSG00000103723 E039 15.7827543 0.002414611 0.808868002 0.90151464 15 82665457 82665575 119 - 1.141 1.165 0.087
ENSG00000103723 E040 0.6064850 0.019387492 0.281024469   15 82665576 82665859 284 - 0.000 0.242 12.851
ENSG00000103723 E041 1.1124618 0.014357751 0.090892365   15 82665860 82665984 125 - 0.000 0.363 13.606
ENSG00000103723 E042 0.5474829 0.026503153 0.430870302   15 82665985 82665997 13 - 0.000 0.193 12.464
ENSG00000103723 E043 19.4523253 0.002253976 0.609253192 0.77641024 15 82666747 82666933 187 - 1.288 1.245 -0.151
ENSG00000103723 E044 0.2027342 0.044987366 1.000000000   15 82675705 82675741 37 - 0.000 0.074 10.939
ENSG00000103723 E045 9.5822925 0.004001769 0.312831246 0.55316473 15 82675742 82676382 641 - 1.043 0.928 -0.427
ENSG00000103723 E046 1.4053658 0.018535282 0.843487071 0.92134635 15 82676383 82676460 78 - 0.325 0.362 0.223
ENSG00000103723 E047 10.9081801 0.023163723 0.392382315 0.62229534 15 82676461 82676505 45 - 1.104 1.001 -0.374
ENSG00000103723 E048 14.3465107 0.012461482 0.350654137 0.58781452 15 82676506 82676637 132 - 1.205 1.104 -0.359
ENSG00000103723 E049 0.2027342 0.044987366 1.000000000   15 82676916 82676950 35 - 0.000 0.074 10.939
ENSG00000103723 E050 0.8092192 0.016784014 0.187697957   15 82676951 82677165 215 - 0.000 0.286 13.155
ENSG00000103723 E051 16.2537668 0.003524475 0.602698836 0.77201439 15 82677274 82677383 110 - 1.141 1.191 0.179
ENSG00000103723 E052 0.6731895 0.039245143 0.040063609   15 82677384 82677454 71 - 0.428 0.074 -3.168
ENSG00000103723 E053 17.0989530 0.003076245 0.987581824 0.99563139 15 82677671 82677803 133 - 1.191 1.192 0.003
ENSG00000103723 E054 13.0508110 0.003256183 0.946757968 0.97569650 15 82678105 82678167 63 - 1.085 1.092 0.025
ENSG00000103723 E055 12.0085948 0.002709641 0.735796358 0.85780493 15 82679729 82679800 72 - 1.021 1.059 0.139
ENSG00000103723 E056 8.2712153 0.016482455 0.294310222 0.53491083 15 82680175 82680229 55 - 0.997 0.858 -0.523
ENSG00000103723 E057 0.6182515 0.019387492 1.000000000   15 82680230 82680410 181 - 0.193 0.193 0.004
ENSG00000103723 E058 17.3671909 0.009523249 0.150513327 0.36303065 15 82680472 82680731 260 - 1.085 1.233 0.529
ENSG00000103723 E059 9.9114220 0.023706732 0.044334001 0.16591593 15 82680732 82680755 24 - 0.738 1.031 1.122
ENSG00000103723 E060 0.5474829 0.026503153 0.430870302   15 82680756 82680836 81 - 0.000 0.193 12.464
ENSG00000103723 E061 11.2423784 0.023621599 0.002248280 0.01871891 15 82680837 82680896 60 - 0.639 1.100 1.788
ENSG00000103723 E062 18.0668307 0.045113857 0.229936004 0.46510025 15 82680897 82681019 123 - 1.084 1.247 0.582
ENSG00000103723 E063 15.7897037 0.026798029 0.926581279 0.96536626 15 82681112 82681178 67 - 1.159 1.151 -0.028
ENSG00000103723 E064 20.0096407 0.017484083 0.318130136 0.55804873 15 82681420 82681580 161 - 1.325 1.224 -0.353
ENSG00000103723 E065 0.1426347 0.031500966 0.155127726   15 82681581 82681601 21 - 0.192 0.000 -14.225
ENSG00000103723 E066 2.7427051 0.008093649 0.003721061 0.02758520 15 82685091 82685913 823 - 0.818 0.363 -2.096
ENSG00000103723 E067 3.6806971 0.047977012 0.064742463 0.21333306 15 82685914 82686814 901 - 0.821 0.512 -1.321
ENSG00000103723 E068 1.6050947 0.099890913 0.336251331 0.57468064 15 82686815 82687019 205 - 0.513 0.324 -1.028
ENSG00000103723 E069 5.8693007 0.031408294 0.021073041 0.09958593 15 82687020 82688019 1000 - 1.000 0.659 -1.335
ENSG00000103723 E070 0.9998973 0.114303688 0.806119412   15 82688020 82688096 77 - 0.325 0.281 -0.290
ENSG00000103723 E071 3.8509152 0.006935004 0.020986867 0.09931043 15 82688097 82688498 402 - 0.854 0.511 -1.455
ENSG00000103723 E072 2.0334760 0.014407664 0.214395042 0.44681979 15 82688499 82688735 237 - 0.579 0.363 -1.095
ENSG00000103723 E073 8.7348257 0.003768760 0.594712359 0.76685702 15 82688736 82688831 96 - 0.972 0.908 -0.241
ENSG00000103723 E074 1.4332679 0.013296742 0.576612446 0.75483671 15 82688832 82688987 156 - 0.427 0.326 -0.583
ENSG00000103723 E075 1.6174088 0.017015099 0.303732233 0.54430711 15 82688988 82689112 125 - 0.509 0.326 -0.995
ENSG00000103723 E076 1.4935551 0.217971723 0.543058016 0.73125965 15 82689113 82689157 45 - 0.430 0.328 -0.582
ENSG00000103723 E077 13.8984728 0.031363676 0.623814031 0.78647926 15 82689158 82689232 75 - 1.161 1.096 -0.230
ENSG00000103723 E078 9.7495852 0.040971947 0.304313069 0.54488801 15 82689378 82689399 22 - 1.084 0.940 -0.531
ENSG00000103723 E079 9.8975666 0.003754845 0.110632543 0.30001677 15 82689400 82689453 54 - 1.105 0.927 -0.653
ENSG00000103723 E080 0.1723744 0.030713503 1.000000000   15 82689763 82689934 172 - 0.000 0.074 10.938
ENSG00000103723 E081 0.2735028 0.026411671 0.424183122   15 82697857 82697978 122 - 0.192 0.074 -1.583
ENSG00000103723 E082 0.0000000       15 82699215 82699240 26 -      
ENSG00000103723 E083 0.1723744 0.030713503 1.000000000   15 82699634 82699901 268 - 0.000 0.074 10.938
ENSG00000103723 E084 0.3447487 0.212789529 0.794808566   15 82701548 82701630 83 - 0.000 0.139 11.877
ENSG00000103723 E085 0.5365243 0.021424306 0.736509415   15 82708772 82709030 259 - 0.193 0.138 -0.579
ENSG00000103723 E086 14.1128383 0.026446548 0.808253558 0.90116679 15 82709594 82710112 519 - 1.142 1.107 -0.125