ENSG00000102786

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311234 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding protein_coding 7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 0.75934283 0.2625097 1.2561609 0.06800566 0.07745906 2.216081 0.10399583 0.08636667 0.09740000 0.011033333 0.920704181 0.001569165 FALSE  
ENST00000476666 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding processed_transcript 7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 0.60926349 0.1802135 0.7362275 0.11815971 0.19957824 1.971996 0.10586667 0.06020000 0.05626667 -0.003933333 0.949397898 0.001569165 TRUE  
ENST00000490542 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding protein_coding 7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 0.20089936 0.0000000 0.7702633 0.00000000 0.17920482 6.285889 0.02128333 0.00000000 0.05993333 0.059933333 0.001569165 0.001569165 FALSE  
ENST00000491189 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding protein_coding 7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 0.09042154 0.3885474 0.0000000 0.38854737 0.00000000 -5.316679 0.02079167 0.11123333 0.00000000 -0.111233333 0.720253359 0.001569165 FALSE  
ENST00000497989 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding protein_coding 7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 2.77846309 0.9888110 4.3839020 0.16345252 0.09536328 2.137219 0.36662083 0.32200000 0.33953333 0.017533333 0.959046965 0.001569165 FALSE  
MSTRG.8775.2 ENSG00000102786 HEK293_OSMI2_6hA HEK293_TMG_6hB INTS6 protein_coding   7.782945 3.127759 12.94406 0.1922947 0.3432435 2.045598 2.45999657 0.9575362 4.4240947 0.12119000 0.21665090 2.196252 0.26442917 0.31303333 0.34293333 0.029900000 0.937272181 0.001569165 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000102786 E001 1.4622227 0.0180385208 0.125760508 0.32508607 13 51335646 51335702 57 - 0.263 0.545 1.592
ENSG00000102786 E002 0.2922838 0.0266976530 0.338938803   13 51337933 51338011 79 - 0.067 0.211 1.908
ENSG00000102786 E003 0.0000000       13 51346402 51346423 22 -      
ENSG00000102786 E004 0.2922838 0.0266976530 0.338938803   13 51346424 51346453 30 - 0.067 0.211 1.908
ENSG00000102786 E005 2.1522407 0.0433538342 0.609362198 0.77646758 13 51354077 51354172 96 - 0.453 0.352 -0.555
ENSG00000102786 E006 1.6702066 0.0857588563 0.933697782 0.96896307 13 51354173 51354176 4 - 0.370 0.353 -0.101
ENSG00000102786 E007 4.6147590 0.0068717401 0.313011526 0.55331034 13 51354177 51354336 160 - 0.712 0.544 -0.733
ENSG00000102786 E008 0.3807181 0.0346695973 0.338713300   13 51361565 51361576 12 - 0.067 0.211 1.913
ENSG00000102786 E009 59.5411814 0.0147522572 0.826127761 0.91155415 13 51361577 51365198 3622 - 1.700 1.688 -0.041
ENSG00000102786 E010 2.0921412 0.0296571974 0.195986020 0.42453613 13 51365199 51365227 29 - 0.477 0.211 -1.681
ENSG00000102786 E011 19.2730311 0.0266600978 0.461010414 0.67386381 13 51365228 51365502 275 - 1.199 1.285 0.303
ENSG00000102786 E012 30.8824479 0.0014691891 0.798640913 0.89553312 13 51365503 51365702 200 - 1.412 1.436 0.084
ENSG00000102786 E013 23.3491246 0.0477041874 0.700000063 0.83563744 13 51365703 51365735 33 - 1.312 1.272 -0.142
ENSG00000102786 E014 36.9090941 0.0011435060 0.498379959 0.69970820 13 51365736 51365845 110 - 1.483 1.534 0.173
ENSG00000102786 E015 42.4458324 0.0013995297 0.150225296 0.36265999 13 51367805 51367898 94 - 1.531 1.626 0.326
ENSG00000102786 E016 104.8745541 0.0004763056 0.956960303 0.98035163 13 51368939 51369310 372 - 1.938 1.941 0.011
ENSG00000102786 E017 73.7421939 0.0007443070 0.596114524 0.76778891 13 51374208 51374439 232 - 1.793 1.772 -0.070
ENSG00000102786 E018 62.1738713 0.0008108813 0.524679593 0.71824549 13 51374654 51374796 143 - 1.721 1.692 -0.099
ENSG00000102786 E019 63.7375287 0.0005937917 0.176191825 0.39870149 13 51376048 51376174 127 - 1.742 1.675 -0.228
ENSG00000102786 E020 75.1429525 0.0015052218 0.900027829 0.95189872 13 51378239 51378454 216 - 1.799 1.799 -0.003
ENSG00000102786 E021 39.0019075 0.0009282554 0.221855535 0.45574177 13 51379462 51379508 47 - 1.502 1.586 0.287
ENSG00000102786 E022 34.9813200 0.0012343378 0.800962743 0.89683978 13 51379509 51379541 33 - 1.469 1.492 0.078
ENSG00000102786 E023 39.3753734 0.0009889757 0.197483213 0.42647564 13 51379542 51379572 31 - 1.539 1.455 -0.288
ENSG00000102786 E024 57.2604285 0.0006776594 0.070503531 0.22573156 13 51382029 51382123 95 - 1.700 1.600 -0.339
ENSG00000102786 E025 66.6729897 0.0007887886 0.032316405 0.13414653 13 51383329 51383461 133 - 1.768 1.657 -0.375
ENSG00000102786 E026 0.9514940 0.0234137117 0.129498128   13 51383462 51383588 127 - 0.176 0.458 1.905
ENSG00000102786 E027 62.5975880 0.0007246037 0.058585462 0.19961751 13 51383589 51383741 153 - 1.738 1.639 -0.337
ENSG00000102786 E028 1.6446483 0.4129556789 0.542171301 0.73061757 13 51383742 51384372 631 - 0.345 0.450 0.582
ENSG00000102786 E029 1.4570612 0.0123740810 0.433404695 0.65375843 13 51384373 51384636 264 - 0.368 0.211 -1.089
ENSG00000102786 E030 1.1530109 0.0152016048 0.648900400   13 51384637 51384707 71 - 0.301 0.211 -0.674
ENSG00000102786 E031 2.8922050 0.0077456948 0.006799521 0.04369452 13 51384744 51385264 521 - 0.602 0.000 -14.383
ENSG00000102786 E032 51.6184680 0.0009906655 0.334583067 0.57318572 13 51387386 51387540 155 - 1.646 1.593 -0.180
ENSG00000102786 E033 49.7525889 0.0007431774 0.786589058 0.88847525 13 51389319 51389444 126 - 1.624 1.613 -0.037
ENSG00000102786 E034 0.6129023 0.0191195577 0.857083590   13 51395299 51395299 1 - 0.176 0.211 0.324
ENSG00000102786 E035 50.0712602 0.0008128585 0.359487054 0.59543026 13 51395300 51395483 184 - 1.636 1.586 -0.171
ENSG00000102786 E036 0.0000000       13 51402529 51402803 275 -      
ENSG00000102786 E037 0.4952057 0.2872081937 0.604420634   13 51421112 51421175 64 - 0.125 0.212 0.917
ENSG00000102786 E038 1.3166394 0.0287641869 0.536406385   13 51421176 51421334 159 - 0.336 0.211 -0.898
ENSG00000102786 E039 0.0000000       13 51421335 51421374 40 -      
ENSG00000102786 E040 0.0000000       13 51423003 51423029 27 -      
ENSG00000102786 E041 0.6544085 0.0189194156 0.852541629   13 51423030 51423090 61 - 0.176 0.211 0.327
ENSG00000102786 E042 0.0000000       13 51430235 51430293 59 -      
ENSG00000102786 E043 21.3569243 0.0017569278 0.327599540 0.56668112 13 51430294 51430304 11 - 1.246 1.335 0.311
ENSG00000102786 E044 31.1391359 0.0016319817 0.322441920 0.56187463 13 51430305 51430383 79 - 1.406 1.483 0.266
ENSG00000102786 E045 34.1517301 0.0012936941 0.287045930 0.52782200 13 51436426 51451024 14599 - 1.446 1.525 0.271
ENSG00000102786 E046 36.0939555 0.0022457020 0.014580019 0.07652711 13 51451025 51451174 150 - 1.446 1.613 0.574
ENSG00000102786 E047 0.3503582 0.0325675293 0.338415449   13 51451309 51451421 113 - 0.067 0.211 1.911
ENSG00000102786 E048 0.3447487 0.5370555437 0.072663483   13 51451422 51451496 75 - 0.000 0.357 12.747
ENSG00000102786 E049 0.5171231 0.8759396651 0.098329983   13 51451497 51451574 78 - 0.000 0.469 13.089
ENSG00000102786 E050 24.0104269 0.0790568338 0.110150914 0.29923563 13 51451978 51452055 78 - 1.260 1.484 0.778
ENSG00000102786 E051 2.0360194 0.0103920391 0.428665336 0.65006816 13 51452056 51452250 195 - 0.397 0.544 0.740
ENSG00000102786 E052 0.1614157 0.0333056232 1.000000000   13 51452251 51452414 164 - 0.067 0.000 -10.565
ENSG00000102786 E053 21.3708884 0.1710176074 0.277991948 0.51807327 13 51452415 51452500 86 - 1.227 1.400 0.603
ENSG00000102786 E054 42.2533652 0.0009980903 0.115858057 0.30890934 13 51452501 51452992 492 - 1.531 1.633 0.348
ENSG00000102786 E055 15.5941821 0.0027741386 0.699036984 0.83501602 13 51452993 51453283 291 - 1.146 1.110 -0.127
ENSG00000102786 E056 0.1779838 0.0354484077 1.000000000   13 51453523 51453592 70 - 0.067 0.000 -10.565
ENSG00000102786 E057 0.0000000       13 51454061 51454264 204 -