ENSG00000101266

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000349736	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	21.826449	15.822446	20.112381	3.4535940	0.4906977	0.3459169	0.2854375	0.26356667	0.1778000	-0.08576667	1.373072e-01	2.805076e-10	FALSE	TRUE
ENST00000400217	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	15.746444	10.790184	31.820487	1.0292005	0.6531291	1.5593534	0.1630542	0.18610000	0.2813000	0.09520000	4.068382e-03	2.805076e-10	FALSE	TRUE
ENST00000642689	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	2.987444	5.569612	0.000000	3.2461418	0.0000000	-9.1240209	0.0479625	0.08566667	0.0000000	-0.08566667	2.805076e-10	2.805076e-10	FALSE	TRUE
ENST00000644885	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	7.689645	8.596519	5.371131	2.2235447	3.1996368	-0.6775204	0.1053083	0.14456667	0.0457000	-0.09886667	6.732185e-01	2.805076e-10	FALSE	TRUE
ENST00000645234	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	11.378813	5.655827	23.488413	1.0651393	1.4035775	2.0522050	0.1233375	0.09843333	0.2084333	0.11000000	6.216698e-02	2.805076e-10	FALSE	TRUE
ENST00000645260	ENSG00000101266	HEK293_OSMI2_6hA	HEK293_TMG_6hB	CSNK2A1	protein_coding	protein_coding	84.61664	58.67449	113.3331	7.970833	4.544184	0.9496451	10.580683	5.161299	15.734307	0.6703339	0.9485225	1.6062315	0.1126208	0.08983333	0.1387667	0.04893333	2.418937e-01	2.805076e-10	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 89
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000101266	E001	0.7076135	5.958224e-02	8.634442e-02		20	472498	472507	10	-	0.102	0.407	2.553
ENSG00000101266	E002	44.0278492	5.977487e-03	1.470198e-01	3.580316e-01	20	472508	473260	753	-	1.605	1.701	0.326
ENSG00000101266	E003	16.5014211	3.269643e-03	6.290047e-02	2.092325e-01	20	473261	473336	76	-	1.297	1.132	-0.585
ENSG00000101266	E004	47.3053108	7.515544e-03	7.316911e-01	8.552905e-01	20	473337	473950	614	-	1.686	1.669	-0.060
ENSG00000101266	E005	43.8144531	9.501727e-04	4.902393e-05	8.178987e-04	20	473951	478464	4514	-	1.537	1.757	0.749
ENSG00000101266	E006	2.6735005	4.540499e-01	7.740408e-01	8.811675e-01	20	478465	478760	296	-	0.600	0.507	-0.432
ENSG00000101266	E007	40.6900636	9.530909e-04	1.379303e-02	7.351624e-02	20	478761	481109	2349	-	1.550	1.689	0.473
ENSG00000101266	E008	9.9557360	3.190739e-03	1.812336e-01	4.055772e-01	20	481110	481146	37	-	0.965	1.106	0.518
ENSG00000101266	E009	14.4943389	2.184672e-03	2.978927e-01	5.383530e-01	20	481147	481149	3	-	1.138	1.233	0.338
ENSG00000101266	E010	17.8339281	1.938640e-03	4.625673e-01	6.748626e-01	20	481150	481154	5	-	1.235	1.298	0.220
ENSG00000101266	E011	41.5574244	2.091511e-03	1.683512e-01	3.883524e-01	20	481155	481191	37	-	1.579	1.661	0.280
ENSG00000101266	E012	279.4098726	2.646924e-04	1.806744e-03	1.574924e-02	20	481192	481622	431	-	2.405	2.477	0.239
ENSG00000101266	E013	988.3700671	1.912756e-03	6.937238e-01	8.315060e-01	20	481623	482710	1088	-	2.988	2.984	-0.011
ENSG00000101266	E014	80.1530816	5.064162e-04	8.007485e-01	8.967418e-01	20	482711	482714	4	-	1.893	1.905	0.040
ENSG00000101266	E015	80.6679446	5.284739e-04	9.963891e-01	9.998864e-01	20	482715	482721	7	-	1.899	1.901	0.006
ENSG00000101266	E016	77.2608111	5.546531e-04	8.236183e-01	9.100566e-01	20	482722	482723	2	-	1.884	1.876	-0.026
ENSG00000101266	E017	105.1057217	4.383145e-04	5.155444e-01	7.119785e-01	20	482724	482731	8	-	2.003	2.028	0.084
ENSG00000101266	E018	91.4388219	4.898695e-04	6.938911e-01	8.316126e-01	20	482732	482735	4	-	1.946	1.963	0.057
ENSG00000101266	E019	90.3202444	6.281871e-04	7.700776e-01	8.787116e-01	20	482736	482741	6	-	1.942	1.955	0.046
ENSG00000101266	E020	89.5281521	5.249001e-04	2.591551e-01	4.980536e-01	20	482742	482747	6	-	1.924	1.970	0.154
ENSG00000101266	E021	126.6563490	6.858791e-04	2.351467e-01	4.710735e-01	20	482748	482776	29	-	2.075	2.118	0.142
ENSG00000101266	E022	127.5272719	4.009162e-04	4.373387e-01	6.567235e-01	20	482777	482781	5	-	2.086	2.113	0.092
ENSG00000101266	E023	309.0983415	9.524106e-04	7.820953e-07	2.294709e-05	20	482782	482856	75	-	2.424	2.551	0.423
ENSG00000101266	E024	222.7057577	1.926577e-03	9.629262e-08	3.587759e-06	20	482857	482864	8	-	2.258	2.433	0.584
ENSG00000101266	E025	217.0799293	1.773005e-03	2.503351e-06	6.351808e-05	20	482865	482886	22	-	2.259	2.412	0.509
ENSG00000101266	E026	272.1477255	7.574189e-04	3.571370e-06	8.624869e-05	20	482887	482921	35	-	2.373	2.492	0.398
ENSG00000101266	E027	1064.3282759	8.380221e-05	2.246906e-07	7.633054e-06	20	482922	483389	468	-	2.992	3.052	0.200
ENSG00000101266	E028	680.6210085	9.685170e-05	3.279085e-02	1.354736e-01	20	483390	483764	375	-	2.810	2.842	0.106
ENSG00000101266	E029	114.3138873	4.889585e-04	5.935522e-01	7.660415e-01	20	483765	483790	26	-	2.044	2.064	0.070
ENSG00000101266	E030	334.8223202	2.247466e-04	4.761444e-02	1.740785e-01	20	483791	483927	137	-	2.500	2.542	0.141
ENSG00000101266	E031	543.0910845	5.697400e-04	4.970873e-03	3.447275e-02	20	483928	484076	149	-	2.704	2.760	0.185
ENSG00000101266	E032	2.0853479	7.411207e-02	2.563131e-01	4.951040e-01	20	484077	484090	14	-	0.563	0.338	-1.177
ENSG00000101266	E033	0.4880035	1.546591e-01	8.525848e-01		20	486364	486375	12	-	0.183	0.145	-0.404
ENSG00000101266	E034	525.7537956	1.679736e-04	2.002674e-02	9.596885e-02	20	486376	486462	87	-	2.695	2.735	0.134
ENSG00000101266	E035	1.7824813	5.102769e-02	1.421693e-01	3.506671e-01	20	486463	487426	964	-	0.531	0.251	-1.614
ENSG00000101266	E036	631.5919616	1.128156e-04	4.084722e-02	1.569234e-01	20	487427	487575	149	-	2.778	2.810	0.107
ENSG00000101266	E037	5.1526003	1.208347e-02	6.983438e-01	8.345099e-01	20	487576	488677	1102	-	0.761	0.813	0.209
ENSG00000101266	E038	627.1314190	1.191371e-04	4.878812e-01	6.925866e-01	20	488678	488778	101	-	2.792	2.783	-0.027
ENSG00000101266	E039	13.6817177	9.641562e-03	1.466089e-01	3.573539e-01	20	488779	489247	469	-	1.214	1.065	-0.537
ENSG00000101266	E040	6.1571948	5.124279e-02	5.459565e-01	7.334036e-01	20	489503	489779	277	-	0.882	0.788	-0.368
ENSG00000101266	E041	590.6126705	1.086762e-04	6.638478e-02	2.169222e-01	20	489780	489881	102	-	2.773	2.747	-0.086
ENSG00000101266	E042	423.8095650	1.241631e-04	7.215194e-02	2.291310e-01	20	492254	492338	85	-	2.631	2.600	-0.101
ENSG00000101266	E043	287.0297204	3.077353e-04	7.192899e-03	4.554510e-02	20	492339	492364	26	-	2.471	2.412	-0.196
ENSG00000101266	E044	3.7140211	3.788087e-01	6.580671e-01	8.087166e-01	20	492365	492717	353	-	0.605	0.733	0.539
ENSG00000101266	E045	0.8048655	1.989694e-02	4.664547e-02		20	494131	494224	94	-	0.367	0.000	-14.195
ENSG00000101266	E046	5.4995006	4.849535e-03	5.372009e-06	1.227022e-04	20	494225	495718	1494	-	0.977	0.252	-3.435
ENSG00000101266	E047	244.3957128	2.177761e-04	4.711333e-02	1.728137e-01	20	495719	495731	13	-	2.397	2.352	-0.151
ENSG00000101266	E048	344.4828951	1.682829e-04	3.553681e-03	2.666918e-02	20	495732	495796	65	-	2.552	2.495	-0.188
ENSG00000101266	E049	240.3125894	2.149429e-04	9.845066e-07	2.801472e-05	20	495797	495802	6	-	2.418	2.301	-0.390
ENSG00000101266	E050	2.1743457	3.887709e-01	3.890231e-01	6.197241e-01	20	495803	496728	926	-	0.569	0.343	-1.172
ENSG00000101266	E051	276.8224225	2.381233e-04	1.211526e-06	3.353081e-05	20	497721	497746	26	-	2.475	2.366	-0.363
ENSG00000101266	E052	336.1017003	1.646242e-04	5.172705e-09	2.592811e-07	20	497747	497780	34	-	2.563	2.445	-0.393
ENSG00000101266	E053	1.9763115	4.887643e-02	4.510189e-02	1.678796e-01	20	497781	498196	416	-	0.255	0.621	1.995
ENSG00000101266	E054	0.6785387	7.040743e-01	4.547622e-01		20	498358	498454	97	-	0.103	0.345	2.189
ENSG00000101266	E055	2.4624251	2.354189e-01	8.116539e-01	9.032601e-01	20	498455	499254	800	-	0.500	0.573	0.342
ENSG00000101266	E056	348.0762019	1.964620e-04	2.022708e-06	5.274104e-05	20	499255	499305	51	-	2.571	2.477	-0.314
ENSG00000101266	E057	4.1874026	6.693242e-03	2.440033e-02	1.103290e-01	20	499306	499524	219	-	0.817	0.472	-1.504
ENSG00000101266	E058	4.4849654	4.037156e-02	3.220261e-01	5.614535e-01	20	499525	499573	49	-	0.782	0.620	-0.677
ENSG00000101266	E059	2.5522874	1.283278e-02	2.796049e-01	5.197159e-01	20	499574	499630	57	-	0.593	0.411	-0.892
ENSG00000101266	E060	1.7686736	2.333841e-01	4.869521e-01	6.918461e-01	20	499631	499832	202	-	0.492	0.342	-0.818
ENSG00000101266	E061	238.4764729	2.925768e-04	1.701784e-03	1.502949e-02	20	499833	499869	37	-	2.402	2.327	-0.250
ENSG00000101266	E062	246.7619592	1.995823e-04	3.295246e-07	1.072458e-05	20	499870	499923	54	-	2.431	2.311	-0.401
ENSG00000101266	E063	162.8242650	3.628670e-04	1.561470e-03	1.404972e-02	20	499924	499934	11	-	2.241	2.150	-0.306
ENSG00000101266	E064	0.6897577	4.767761e-02	5.320236e-01		20	499935	500030	96	-	0.255	0.144	-1.023
ENSG00000101266	E065	2.6000705	9.370984e-03	7.881077e-01	8.894322e-01	20	500031	500115	85	-	0.530	0.574	0.203
ENSG00000101266	E066	1.1659948	1.405894e-02	8.981819e-01		20	500116	500171	56	-	0.314	0.338	0.150
ENSG00000101266	E067	2.9782158	7.728270e-02	6.252749e-01	7.874909e-01	20	500172	500760	589	-	0.625	0.526	-0.448
ENSG00000101266	E068	5.3495731	7.531343e-03	3.439536e-01	5.815767e-01	20	500761	503064	2304	-	0.852	0.725	-0.504
ENSG00000101266	E069	1.5478282	2.149561e-02	9.706759e-01	9.871789e-01	20	503065	503281	217	-	0.414	0.409	-0.027
ENSG00000101266	E070	1.3102221	2.979316e-01	6.794709e-01		20	503307	503695	389	-	0.317	0.410	0.550
ENSG00000101266	E071	3.4001504	6.916472e-02	1.838573e-01	4.089322e-01	20	504166	505117	952	-	0.722	0.471	-1.129
ENSG00000101266	E072	252.9020022	2.300390e-04	4.794569e-03	3.349768e-02	20	505118	505229	112	-	2.421	2.357	-0.214
ENSG00000101266	E073	0.4054685	3.394884e-01	1.794721e-01		20	505230	505250	21	-	0.000	0.260	11.522
ENSG00000101266	E074	2.1953396	3.684857e-01	3.606873e-01	5.961842e-01	20	505911	508450	2540	-	0.572	0.343	-1.184
ENSG00000101266	E075	313.3765703	2.271971e-04	3.319754e-03	2.532020e-02	20	508451	508605	155	-	2.513	2.452	-0.202
ENSG00000101266	E076	156.3024864	3.256767e-04	5.938059e-02	2.014099e-01	20	508606	508621	16	-	2.211	2.157	-0.181
ENSG00000101266	E077	210.7164231	5.488142e-04	2.084543e-02	9.883233e-02	20	508622	508660	39	-	2.343	2.283	-0.202
ENSG00000101266	E078	1.3143091	1.976092e-02	2.614885e-01		20	510168	510338	171	-	0.455	0.251	-1.243
ENSG00000101266	E079	0.0000000				20	526696	526942	247	-
ENSG00000101266	E080	34.3760910	1.056925e-03	1.011882e-01	2.839378e-01	20	527933	528049	117	-	1.578	1.478	-0.343
ENSG00000101266	E081	0.6370325	3.476013e-02	1.690208e-01		20	539199	539674	476	-	0.102	0.338	2.149
ENSG00000101266	E082	0.8397668	1.726718e-02	7.389310e-02		20	539675	539824	150	-	0.102	0.410	2.566
ENSG00000101266	E083	0.8397668	1.726718e-02	7.389310e-02		20	539825	540009	185	-	0.102	0.410	2.566
ENSG00000101266	E084	0.1723744	3.485975e-02	3.352272e-01		20	540828	540889	62	-	0.000	0.144	11.456
ENSG00000101266	E085	0.3337900	2.744240e-02	7.751172e-01		20	540890	541099	210	-	0.102	0.144	0.566
ENSG00000101266	E086	0.1723744	3.485975e-02	3.352272e-01		20	543054	543387	334	-	0.000	0.144	11.456
ENSG00000101266	E087	0.3150090	2.799160e-02	7.733991e-01		20	543388	543631	244	-	0.102	0.144	0.568
ENSG00000101266	E088	0.3447487	5.675402e-01	2.267051e-01		20	543632	543671	40	-	0.000	0.256	11.313
ENSG00000101266	E089	195.1951769	6.680195e-04	6.024361e-02	2.033704e-01	20	543672	543835	164	-	2.306	2.254	-0.174

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000101266

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3