ENSG00000101057

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000217026	ENSG00000101057	HEK293_OSMI2_6hA	HEK293_TMG_6hB	MYBL2	protein_coding	protein_coding	273.8858	405.2283	125.0548	76.72572	3.87652	-1.696094	73.505	108.6867	18.97696	23.17563	0.9681607	-2.517227	0.2805083	0.2649000	0.1523000	-0.1126000	0.001027203	0.001027203	FALSE	TRUE
MSTRG.20728.33	ENSG00000101057	HEK293_OSMI2_6hA	HEK293_TMG_6hB	MYBL2	protein_coding		273.8858	405.2283	125.0548	76.72572	3.87652	-1.696094	159.663	252.4121	92.42929	49.33145	4.8341160	-1.449260	0.5811167	0.6207333	0.7381667	0.1174333	0.018147046	0.001027203	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
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width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000101057	E001	1.1832303	8.856362e-02	6.105948e-01		20	43657990	43658022	33	+	0.214	0.328	0.827
ENSG00000101057	E002	1.0164654	3.295498e-02	5.816310e-01		20	43658023	43658036	14	+	0.357	0.258	-0.653
ENSG00000101057	E003	0.9576510	1.661250e-02	1.073284e-01		20	43658037	43658071	35	+	0.464	0.173	-1.964
ENSG00000101057	E004	0.1308682	3.264919e-02	1.000000e+00		20	43667019	43667030	12	+	0.000	0.066	9.740
ENSG00000101057	E005	0.3336024	2.444117e-02	1.000000e+00		20	43667031	43667039	9	+	0.000	0.123	10.838
ENSG00000101057	E006	0.9114452	5.323401e-02	2.961449e-01		20	43667040	43667041	2	+	0.000	0.261	11.926
ENSG00000101057	E007	1.4654653	1.271367e-02	4.854903e-01	6.909079e-01	20	43667042	43667051	10	+	0.214	0.363	1.036
ENSG00000101057	E008	1.4654653	1.271367e-02	4.854903e-01	6.909079e-01	20	43667052	43667053	2	+	0.214	0.363	1.036
ENSG00000101057	E009	1.9299359	1.086478e-02	2.753563e-01	5.154056e-01	20	43667054	43667057	4	+	0.214	0.446	1.494
ENSG00000101057	E010	2.6561427	2.284333e-02	1.171047e-01	3.109979e-01	20	43667058	43667064	7	+	0.214	0.556	2.027
ENSG00000101057	E011	6.3491452	2.139198e-01	5.819796e-01	7.583751e-01	20	43667065	43667085	21	+	0.876	0.754	-0.479
ENSG00000101057	E012	7.1472181	2.508560e-01	7.435410e-01	8.626928e-01	20	43667086	43667086	1	+	0.877	0.811	-0.255
ENSG00000101057	E013	7.9019472	1.035421e-01	5.006144e-01	7.011905e-01	20	43667087	43667090	4	+	0.942	0.842	-0.382
ENSG00000101057	E014	10.2887190	2.761313e-02	8.670260e-01	9.343578e-01	20	43667091	43667093	3	+	0.969	0.966	-0.010
ENSG00000101057	E015	13.8406776	4.187443e-03	7.804859e-01	8.850462e-01	20	43667094	43667105	12	+	1.049	1.094	0.161
ENSG00000101057	E016	16.5116708	1.157851e-02	4.574966e-01	6.714264e-01	20	43667106	43667107	2	+	1.074	1.178	0.373
ENSG00000101057	E017	17.7141147	1.598305e-02	4.488696e-01	6.649001e-01	20	43667108	43667110	3	+	1.097	1.208	0.396
ENSG00000101057	E018	19.4646617	1.730610e-02	4.775048e-01	6.853790e-01	20	43667111	43667113	3	+	1.139	1.245	0.376
ENSG00000101057	E019	337.6571631	8.441187e-04	3.499156e-12	3.277645e-10	20	43667114	43667303	190	+	2.252	2.474	0.740
ENSG00000101057	E020	0.3751086	3.288828e-02	1.000000e+00		20	43669523	43669556	34	+	0.000	0.123	10.746
ENSG00000101057	E021	0.8570750	1.387942e-01	2.978044e-01		20	43671340	43671342	3	+	0.000	0.290	11.867
ENSG00000101057	E022	1.4939199	1.972452e-02	7.511302e-02	2.350671e-01	20	43671343	43671373	31	+	0.000	0.419	13.223
ENSG00000101057	E023	1.2018237	1.537876e-02	1.227085e-01		20	43671374	43671374	1	+	0.000	0.362	12.992
ENSG00000101057	E024	2.3850540	8.162879e-02	1.704911e-01	3.910933e-01	20	43671375	43671433	59	+	0.214	0.530	1.912
ENSG00000101057	E025	4.5192808	2.413566e-01	8.733551e-01	9.378171e-01	20	43673708	43673805	98	+	0.748	0.633	-0.479
ENSG00000101057	E026	931.8082071	9.938325e-05	3.626827e-01	5.978980e-01	20	43673806	43673899	94	+	2.858	2.882	0.079
ENSG00000101057	E027	1327.2785846	1.388862e-04	1.115674e-02	6.303384e-02	20	43681784	43681855	72	+	3.049	3.025	-0.078
ENSG00000101057	E028	1789.5735266	5.879964e-05	8.412265e-09	4.019685e-07	20	43682794	43682886	93	+	3.200	3.150	-0.165
ENSG00000101057	E029	18.1683286	4.307915e-02	6.110609e-01	7.776530e-01	20	43682887	43682915	29	+	1.246	1.183	-0.225
ENSG00000101057	E030	2830.8738624	6.001341e-05	3.722621e-10	2.344037e-08	20	43686852	43687072	221	+	3.393	3.350	-0.142
ENSG00000101057	E031	2.7737821	1.346432e-01	8.232502e-01	9.098053e-01	20	43690251	43690348	98	+	0.552	0.508	-0.208
ENSG00000101057	E032	0.5171231	1.101704e+00	1.000000e+00		20	43691053	43691106	54	+	0.000	0.179	10.514
ENSG00000101057	E033	13.9572899	2.532696e-03	5.203998e-02	1.845046e-01	20	43692121	43692135	15	+	1.229	1.040	-0.676
ENSG00000101057	E034	18.4214314	2.923601e-03	1.514196e-01	3.644092e-01	20	43692136	43692156	21	+	1.290	1.163	-0.446
ENSG00000101057	E035	2293.8135705	1.256007e-04	2.102811e-04	2.787057e-03	20	43692157	43692319	163	+	3.289	3.261	-0.095
ENSG00000101057	E036	0.5365243	2.998540e-02	5.751507e-01		20	43698288	43698327	40	+	0.214	0.123	-0.960
ENSG00000101057	E037	3163.7340273	1.408263e-04	9.361777e-10	5.499291e-08	20	43699757	43700044	288	+	3.443	3.397	-0.156
ENSG00000101057	E038	3792.9786279	6.550157e-05	3.350201e-06	8.163011e-05	20	43702490	43702903	414	+	3.506	3.481	-0.085
ENSG00000101057	E039	1103.1063249	2.996255e-04	2.531072e-02	1.131621e-01	20	43705219	43705242	24	+	2.971	2.945	-0.086
ENSG00000101057	E040	1974.1801101	6.821459e-04	3.553906e-02	1.430158e-01	20	43705243	43705358	116	+	3.222	3.195	-0.088
ENSG00000101057	E041	2048.8929907	1.696086e-04	3.743538e-01	6.076589e-01	20	43709963	43710062	100	+	3.220	3.218	-0.005
ENSG00000101057	E042	134.1653967	2.418124e-02	1.759294e-02	8.761285e-02	20	43710326	43710810	485	+	2.189	1.987	-0.677
ENSG00000101057	E043	38.5816859	6.678519e-02	9.774049e-01	9.904517e-01	20	43711443	43711487	45	+	1.500	1.505	0.015
ENSG00000101057	E044	2440.4757098	1.161602e-04	3.107533e-03	2.406432e-02	20	43711488	43711601	114	+	3.263	3.302	0.130
ENSG00000101057	E045	2367.8378948	2.236590e-04	2.373743e-05	4.420534e-04	20	43713002	43713106	105	+	3.234	3.290	0.188
ENSG00000101057	E046	2926.2831700	7.045692e-05	1.712838e-13	2.038397e-11	20	43715134	43715283	150	+	3.312	3.388	0.251
ENSG00000101057	E047	4053.2235537	1.121095e-03	4.377255e-12	4.039992e-10	20	43715959	43716495	537	+	3.410	3.534	0.412

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000101057

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3