ENSG00000099204

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369253 ENSG00000099204 HEK293_OSMI2_6hA HEK293_TMG_6hB ABLIM1 protein_coding protein_coding 13.59056 12.15488 15.52348 2.455103 1.460245 0.3526596 0.4896725 0.1956037 1.132113 0.04778708 0.2802903 2.4737670 0.03310833 0.01596667 0.07533333 0.05936667 0.04057472 0.01385334 FALSE TRUE
ENST00000392952 ENSG00000099204 HEK293_OSMI2_6hA HEK293_TMG_6hB ABLIM1 protein_coding protein_coding 13.59056 12.15488 15.52348 2.455103 1.460245 0.3526596 9.3987209 9.7276545 8.484371 2.27690543 1.3095449 -0.1970672 0.70858750 0.78726667 0.53983333 -0.24743333 0.01385334 0.01385334 FALSE TRUE
MSTRG.4676.4 ENSG00000099204 HEK293_OSMI2_6hA HEK293_TMG_6hB ABLIM1 protein_coding   13.59056 12.15488 15.52348 2.455103 1.460245 0.3526596 1.3405143 0.3586796 3.082123 0.16835384 0.0981452 3.0681584 0.08903750 0.03653333 0.20133333 0.16480000 0.08077041 0.01385334 FALSE TRUE
MSTRG.4676.9 ENSG00000099204 HEK293_OSMI2_6hA HEK293_TMG_6hB ABLIM1 protein_coding   13.59056 12.15488 15.52348 2.455103 1.460245 0.3526596 0.7183998 0.1514498 1.256188 0.15144976 0.4530719 2.9713344 0.04810417 0.01223333 0.08500000 0.07276667 0.29381564 0.01385334 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000099204 E001 0.7392585 0.03851516 0.37028657   10 114431112 114431112 1 - 0.107 0.327 2.000
ENSG00000099204 E002 320.7450537 1.17374863 0.23483530 0.47065167 10 114431113 114431893 781 - 2.203 2.721 1.726
ENSG00000099204 E003 303.9804337 1.20515705 0.30595245 0.54660162 10 114431894 114432615 722 - 2.241 2.671 1.433
ENSG00000099204 E004 761.2974390 1.67114220 0.51902108 0.71436910 10 114432616 114435440 2825 - 2.742 3.009 0.889
ENSG00000099204 E005 111.0451462 0.70464854 0.43660095 0.65619123 10 114435441 114435953 513 - 1.948 2.146 0.663
ENSG00000099204 E006 39.4572094 0.37603284 0.54805952 0.73491658 10 114435954 114436017 64 - 1.544 1.671 0.432
ENSG00000099204 E007 54.0972671 0.48956999 0.58682527 0.76150340 10 114436018 114436096 79 - 1.691 1.792 0.339
ENSG00000099204 E008 62.3124378 0.56460626 0.69524117 0.83241403 10 114436097 114436177 81 - 1.781 1.819 0.127
ENSG00000099204 E009 90.5330634 0.68559494 0.64605543 0.80088929 10 114436178 114436373 196 - 1.926 1.996 0.233
ENSG00000099204 E010 49.0599538 0.00479823 0.13008261 0.33196901 10 114437844 114437924 81 - 1.676 1.738 0.210
ENSG00000099204 E011 51.3737503 0.01689885 0.06361723 0.21086912 10 114439176 114439250 75 - 1.697 1.736 0.133
ENSG00000099204 E012 2.6537527 0.12465361 0.34089779 0.57884182 10 114439617 114440081 465 - 0.382 0.709 1.548
ENSG00000099204 E013 34.8198056 0.04221645 0.27477098 0.51475617 10 114440082 114440089 8 - 1.513 1.593 0.273
ENSG00000099204 E014 53.7698992 0.07880839 0.21023468 0.44211114 10 114441017 114441077 61 - 1.721 1.752 0.105
ENSG00000099204 E015 61.9655864 0.08252253 0.13451888 0.33890025 10 114441722 114441786 65 - 1.800 1.790 -0.032
ENSG00000099204 E016 59.3645092 0.07696361 0.06436207 0.21247677 10 114444029 114444085 57 - 1.799 1.747 -0.174
ENSG00000099204 E017 57.5068509 0.07609899 0.11193279 0.30230510 10 114444086 114444134 49 - 1.769 1.757 -0.039
ENSG00000099204 E018 71.1957968 0.05981974 0.04911109 0.17746223 10 114445312 114445403 92 - 1.868 1.835 -0.111
ENSG00000099204 E019 73.2647645 0.08112779 0.08926022 0.26240652 10 114447880 114448020 141 - 1.880 1.848 -0.111
ENSG00000099204 E020 4.6947347 0.19330190 0.05006385 0.17983361 10 114448021 114448026 6 - 0.850 0.568 -1.172
ENSG00000099204 E021 0.4341107 0.02678780 0.10937801   10 114450079 114450135 57 - 0.000 0.324 20.651
ENSG00000099204 E022 32.7603607 0.12705461 0.17926016 0.40296638 10 114451624 114451644 21 - 1.544 1.498 -0.156
ENSG00000099204 E023 37.0121126 0.13041261 0.22973964 0.46485255 10 114451645 114451671 27 - 1.581 1.567 -0.049
ENSG00000099204 E024 1.5939484 0.37387958 0.89762502 0.95063212 10 114453379 114453483 105 - 0.334 0.498 0.894
ENSG00000099204 E025 0.1779838 0.33294037 0.44384438   10 114463045 114463164 120 - 0.108 0.000 -18.309
ENSG00000099204 E026 0.0000000       10 114465465 114465697 233 -      
ENSG00000099204 E027 70.8005093 0.08329754 0.06938666 0.22353552 10 114465698 114465827 130 - 1.877 1.819 -0.194
ENSG00000099204 E028 38.3621180 0.08355140 0.06396267 0.21159699 10 114468181 114468216 36 - 1.619 1.553 -0.226
ENSG00000099204 E029 0.0000000       10 114468217 114468265 49 -      
ENSG00000099204 E030 86.3684408 0.10624154 0.02781793 0.12076907 10 114472977 114473132 156 - 1.994 1.850 -0.484
ENSG00000099204 E031 48.1038253 0.08828815 0.06105659 0.20513817 10 114473879 114473956 78 - 1.721 1.640 -0.275
ENSG00000099204 E032 0.1723744 0.07437381 0.56730091   10 114481479 114481526 48 - 0.000 0.137 19.073
ENSG00000099204 E033 0.0000000       10 114485297 114485380 84 -      
ENSG00000099204 E034 51.6976138 0.05495863 0.01008576 0.05852338 10 114487958 114488016 59 - 1.765 1.648 -0.396
ENSG00000099204 E035 56.1584046 0.05308600 0.01222274 0.06733830 10 114491791 114491878 88 - 1.791 1.697 -0.319
ENSG00000099204 E036 4.2562662 0.00630307 0.58219039 0.75849112 10 114526639 114526659 21 - 0.611 0.818 0.857
ENSG00000099204 E037 68.4006164 0.05024572 0.01246051 0.06829151 10 114526660 114526931 272 - 1.867 1.793 -0.249
ENSG00000099204 E038 2.8271952 0.09834469 0.39821794 0.62682780 10 114545005 114545098 94 - 0.583 0.559 -0.109
ENSG00000099204 E039 0.0000000       10 114547491 114547649 159 -      
ENSG00000099204 E040 4.6450097 0.10905463 0.18832569 0.41483388 10 114547650 114547776 127 - 0.784 0.679 -0.426
ENSG00000099204 E041 3.7033768 0.07213196 0.17387936 0.39570528 10 114571297 114571406 110 - 0.716 0.600 -0.493
ENSG00000099204 E042 4.6555931 0.02980507 0.53352223 0.72456812 10 114575416 114575599 184 - 0.717 0.768 0.205
ENSG00000099204 E043 0.0000000       10 114595002 114595133 132 -      
ENSG00000099204 E044 3.0188125 0.16505600 0.16505309 0.38403178 10 114601827 114601961 135 - 0.329 0.781 2.152
ENSG00000099204 E045 0.0000000       10 114610629 114610717 89 -      
ENSG00000099204 E046 0.5778428 0.06121522 0.11415129   10 114631902 114632092 191 - 0.000 0.328 20.670
ENSG00000099204 E047 0.0000000       10 114657957 114658283 327 -      
ENSG00000099204 E048 0.0000000       10 114684290 114685003 714 -      
ENSG00000099204 E049 0.8507255 0.10551659 0.03188042   10 114768061 114768061 1 - 0.000 0.458 21.404