ENSG00000090857

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000288050 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding protein_coding 15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 1.1409020 1.2497691 0.8208157 0.3317848 0.1835339 -0.6005590 0.07805417 0.06400000 0.06170000 -0.00230000 1.00000000 0.03200795 FALSE TRUE
ENST00000398122 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding protein_coding 15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 1.2005949 0.8545458 1.2180940 0.4780451 0.6582334 0.5064067 0.08258333 0.04220000 0.09183333 0.04963333 0.94405898 0.03200795 FALSE TRUE
ENST00000569042 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding protein_coding 15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 4.8420198 7.8505759 1.5481883 1.0641780 0.5214061 -2.3347654 0.30118750 0.40486667 0.11546667 -0.28940000 0.03200795 0.03200795 FALSE TRUE
MSTRG.12917.2 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding   15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 3.3479776 4.8720724 4.1975973 1.2894970 0.1384819 -0.2144970 0.22267917 0.23970000 0.31616667 0.07646667 0.68172041 0.03200795 FALSE TRUE
MSTRG.12917.3 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding   15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 0.5404323 0.4514323 1.1829009 0.4514323 0.6037316 1.3702832 0.03802500 0.02343333 0.09016667 0.06673333 0.62850794 0.03200795 FALSE TRUE
MSTRG.12917.5 ENSG00000090857 HEK293_OSMI2_6hA HEK293_TMG_6hB PDPR protein_coding   15.28588 19.83485 13.32857 1.298018 0.4581574 -0.5731608 1.1908181 0.6600688 0.3921295 0.5420866 0.3921295 -0.7366492 0.08051250 0.03593333 0.02833333 -0.00760000 0.85357621 0.03200795 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000090857 E001 2.6655919 0.119184879 0.192840526 0.42059488 16 70114129 70114295 167 +      
ENSG00000090857 E002 2.5347237 0.131116176 0.145202199 0.35520481 16 70114296 70114300 5 +      
ENSG00000090857 E003 4.6752976 0.135035891 0.222932859 0.45687128 16 70114301 70114331 31 +      
ENSG00000090857 E004 4.0919473 0.324626472 0.923749467 0.96426230 16 70114332 70114340 9 +      
ENSG00000090857 E005 4.5545803 0.350491515 0.782633243 0.88619238 16 70114341 70114342 2 +      
ENSG00000090857 E006 5.2199475 0.399710692 0.740755338 0.86090002 16 70114343 70114343 1 +      
ENSG00000090857 E007 15.3082027 0.096302074 0.137677919 0.34395842 16 70114344 70114371 28 +      
ENSG00000090857 E008 26.0607276 0.089794748 0.067484494 0.21940955 16 70114372 70114440 69 +      
ENSG00000090857 E009 5.4968984 0.041258679 0.671847840 0.81748168 16 70114821 70114869 49 +      
ENSG00000090857 E010 7.6279887 0.014911151 0.664142410 0.81248752 16 70114870 70114930 61 +      
ENSG00000090857 E011 6.1132421 0.276733881 0.476004290 0.68425237 16 70120131 70120460 330 +      
ENSG00000090857 E012 69.2330186 0.107367577 0.088355655 0.26071477 16 70120461 70120719 259 +      
ENSG00000090857 E013 59.9734543 0.099786168 0.041167601 0.15777229 16 70127260 70127393 134 +      
ENSG00000090857 E014 52.3897092 0.099909070 0.043151410 0.16294085 16 70128784 70128865 82 +      
ENSG00000090857 E015 2.4709378 0.009323819 0.003171949 0.02444388 16 70128866 70128958 93 +      
ENSG00000090857 E016 64.7966877 0.114769534 0.068684412 0.22211164 16 70128959 70129122 164 +      
ENSG00000090857 E017 44.6859460 0.087179011 0.115472664 0.30824959 16 70130423 70130544 122 +      
ENSG00000090857 E018 28.4270376 0.123691510 0.255753531 0.49444829 16 70131302 70131419 118 +      
ENSG00000090857 E019 0.5061644 0.079873545 1.000000000   16 70131933 70131985 53 +      
ENSG00000090857 E020 63.6053642 0.140851922 0.130581532 0.33271440 16 70132151 70132300 150 +      
ENSG00000090857 E021 68.5933678 0.074301982 0.095980804 0.27470486 16 70136194 70136386 193 +      
ENSG00000090857 E022 53.0478932 0.357017895 0.587158845 0.76175001 16 70138899 70139023 125 +      
ENSG00000090857 E023 88.6923199 0.012029537 0.001640336 0.01460240 16 70142234 70142389 156 +      
ENSG00000090857 E024 4.8140353 0.006004847 0.854980594 0.92757873 16 70142471 70142552 82 +      
ENSG00000090857 E025 89.3544306 0.067857499 0.028595432 0.12313409 16 70142553 70142686 134 +      
ENSG00000090857 E026 51.5727492 0.067686664 0.056253405 0.19421126 16 70143510 70143658 149 +      
ENSG00000090857 E027 43.7004992 0.028318631 0.006541087 0.04241741 16 70144421 70144533 113 +      
ENSG00000090857 E028 0.0000000       16 70145727 70145748 22 +      
ENSG00000090857 E029 0.0000000       16 70145755 70145794 40 +      
ENSG00000090857 E030 0.0000000       16 70145795 70145797 3 +      
ENSG00000090857 E031 0.0000000       16 70145798 70145803 6 +      
ENSG00000090857 E032 0.0000000       16 70145804 70145833 30 +      
ENSG00000090857 E033 0.1779838 0.286041813 0.235949851   16 70145834 70146133 300 +      
ENSG00000090857 E034 63.8673947 0.035873670 0.001457041 0.01331750 16 70146134 70146228 95 +      
ENSG00000090857 E035 0.9824014 0.015127767 0.950247139   16 70147541 70147673 133 +      
ENSG00000090857 E036 82.7329343 0.051004134 0.027690837 0.12037070 16 70148464 70148553 90 +      
ENSG00000090857 E037 0.3032425 0.024441170 0.544637530   16 70148554 70148591 38 +      
ENSG00000090857 E038 96.2068628 0.027112393 0.330019083 0.56895995 16 70153391 70153573 183 +      
ENSG00000090857 E039 2339.3714197 0.469636978 0.151428219 0.36440922 16 70156475 70162537 6063 +