ENSG00000087502

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360150 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding protein_coding 29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 1.973928 0.3750750 3.911847 0.06816858 0.0435105 3.348322 0.06987500 0.06260000 0.0637000 0.00110000 1.000000e+00 3.795077e-10 FALSE TRUE
ENST00000548909 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding protein_coding 29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 0.423931 0.4158234 0.000000 0.41582342 0.0000000 -5.412183 0.05657083 0.07236667 0.0000000 -0.07236667 6.134194e-01 3.795077e-10 FALSE TRUE
ENST00000551467 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding protein_coding 29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 5.540465 0.9833281 12.668270 0.71017824 0.5511724 3.673944 0.15690833 0.15463333 0.2064000 0.05176667 8.128792e-01 3.795077e-10 FALSE TRUE
ENST00000552155 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding protein_coding 29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 9.242778 1.5802146 19.861346 0.43023470 1.5231718 3.643396 0.24625417 0.26673333 0.3223667 0.05563333 8.415926e-01 3.795077e-10 FALSE FALSE
MSTRG.7044.3 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding   29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 8.626051 2.1389961 17.208019 0.35833107 0.1137113 3.002184 0.33429583 0.35730000 0.2804000 -0.07690000 7.675298e-01 3.795077e-10 TRUE TRUE
MSTRG.7044.5 ENSG00000087502 HEK293_OSMI2_6hA HEK293_TMG_6hB ERGIC2 protein_coding   29.53483 6.006901 61.45464 0.2624016 1.475765 3.352664 2.886406 0.0000000 6.450934 0.00000000 0.8258588 9.335599 0.06972083 0.00000000 0.1044333 0.10443333 3.795077e-10 3.795077e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000087502 E001 10.6809579 0.0030731535 0.52026717 0.71512715 12 29337352 29337587 236 - 0.883 1.003 0.451
ENSG00000087502 E002 42.7635919 0.0009883071 0.05464494 0.19053811 12 29337588 29338642 1055 - 1.426 1.603 0.606
ENSG00000087502 E003 13.4273311 0.0035413537 0.96890451 0.98629618 12 29338643 29338869 227 - 0.977 1.004 0.100
ENSG00000087502 E004 13.5793833 0.0067111756 0.47052627 0.68044103 12 29338870 29338977 108 - 0.988 0.917 -0.263
ENSG00000087502 E005 71.7908206 0.0040634678 0.01388671 0.07389263 12 29338978 29339850 873 - 1.685 1.538 -0.499
ENSG00000087502 E006 179.7875193 0.0139219067 0.44360972 0.66113037 12 29339851 29340856 1006 - 2.054 2.129 0.253
ENSG00000087502 E007 99.5476042 1.4398259983 0.38894024 0.61965606 12 29340857 29341017 161 - 1.757 2.082 1.096
ENSG00000087502 E008 28.3085950 0.7587735247 0.17616010 0.39865724 12 29341018 29341019 2 - 1.203 1.634 1.491
ENSG00000087502 E009 29.6368834 0.7769716051 0.19097129 0.41811869 12 29341020 29341032 13 - 1.225 1.641 1.435
ENSG00000087502 E010 137.0925949 0.0740814689 0.10840868 0.29641064 12 29341033 29341218 186 - 1.916 2.131 0.721
ENSG00000087502 E011 91.2635413 0.0156443226 0.30881346 0.54933448 12 29341734 29341761 28 - 1.760 1.870 0.372
ENSG00000087502 E012 109.8406518 0.0013109163 0.50635982 0.70517819 12 29341762 29341816 55 - 1.845 1.913 0.231
ENSG00000087502 E013 1.4486913 0.2756522923 1.00000000 1.00000000 12 29341817 29341865 49 - 0.285 0.277 -0.057
ENSG00000087502 E014 120.1437094 0.0054851618 0.48660770 0.69166242 12 29343120 29343162 43 - 1.880 1.952 0.243
ENSG00000087502 E015 162.1962837 0.0035140382 0.61772636 0.78226157 12 29343163 29343244 82 - 2.011 2.070 0.198
ENSG00000087502 E016 135.5306402 0.0100682480 0.91332340 0.95874173 12 29343245 29343282 38 - 1.936 1.962 0.085
ENSG00000087502 E017 176.6227597 0.0058514498 0.45260655 0.66758444 12 29345443 29345540 98 - 2.055 2.049 -0.019
ENSG00000087502 E018 0.6494192 0.0208893518 0.44784958   12 29345541 29345557 17 - 0.128 0.281 1.406
ENSG00000087502 E019 89.3940958 0.0027117539 0.57304589 0.75234922 12 29349079 29349100 22 - 1.762 1.765 0.008
ENSG00000087502 E020 98.3328028 0.0042450377 0.50246632 0.70248654 12 29349101 29349144 44 - 1.804 1.798 -0.020
ENSG00000087502 E021 70.2016101 0.0062063566 0.14600215 0.35638139 12 29349145 29349158 14 - 1.667 1.592 -0.255
ENSG00000087502 E022 65.6290503 0.0006770493 0.13560456 0.34072713 12 29349159 29349177 19 - 1.640 1.572 -0.230
ENSG00000087502 E023 107.7339163 0.0017537057 0.37682489 0.60969147 12 29350013 29350068 56 - 1.845 1.833 -0.039
ENSG00000087502 E024 111.4655946 0.0005885393 0.06161514 0.20642876 12 29356382 29356427 46 - 1.867 1.804 -0.213
ENSG00000087502 E025 112.4604574 0.0040255833 0.28845126 0.52915707 12 29356428 29356477 50 - 1.864 1.839 -0.085
ENSG00000087502 E026 165.6225631 0.0042432679 0.34796736 0.58540241 12 29357623 29357724 102 - 2.029 2.018 -0.036
ENSG00000087502 E027 130.6040751 0.0003513856 0.38658131 0.61776400 12 29361645 29361685 41 - 1.927 1.922 -0.017
ENSG00000087502 E028 156.4806509 0.0003658930 0.17201956 0.39321701 12 29366877 29366947 71 - 2.007 1.984 -0.079
ENSG00000087502 E029 115.3079579 0.0003716981 0.25416455 0.49259499 12 29368241 29368287 47 - 1.878 1.856 -0.074
ENSG00000087502 E030 140.1780830 0.0003379336 0.06140497 0.20592371 12 29370114 29370168 55 - 1.964 1.913 -0.172
ENSG00000087502 E031 146.5261102 0.0023774017 0.11218048 0.30275756 12 29370169 29370222 54 - 1.981 1.940 -0.138
ENSG00000087502 E032 204.2366449 0.0040051263 0.10194787 0.28528974 12 29371528 29371670 143 - 2.123 2.086 -0.126
ENSG00000087502 E033 0.1779838 0.0374501370 0.75920766   12 29372464 29372520 57 - 0.047 0.001 -6.168
ENSG00000087502 E034 0.8759238 0.0200032889 0.11392574   12 29372855 29372967 113 - 0.128 0.450 2.404
ENSG00000087502 E035 0.6294705 0.0340525604 0.45837331   12 29380575 29381114 540 - 0.128 0.280 1.397
ENSG00000087502 E036 98.7839623 0.0062209442 0.52330154 0.71733048 12 29381115 29381228 114 - 1.806 1.802 -0.013