ENSG00000083168

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-4 / 4
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000265713	ENSG00000083168	HEK293_OSMI2_6hA	HEK293_TMG_6hB	KAT6A	protein_coding	protein_coding	11.0016	7.438229	15.86061	1.769418	0.7499474	1.091389	5.9112101	6.1690843	6.843230	1.8258904	0.87234785	0.1493911	0.64057083	0.79870000	0.4290333	-0.36966667	2.771131e-02	3.691241e-14	FALSE	TRUE
ENST00000396930	ENSG00000083168	HEK293_OSMI2_6hA	HEK293_TMG_6hB	KAT6A	protein_coding	protein_coding	11.0016	7.438229	15.86061	1.769418	0.7499474	1.091389	3.0570000	0.6389729	5.531303	0.1315028	0.62591634	3.0939949	0.20082083	0.08790000	0.3496333	0.26173333	2.557750e-06	3.691241e-14	FALSE	TRUE
ENST00000648335	ENSG00000083168	HEK293_OSMI2_6hA	HEK293_TMG_6hB	KAT6A	protein_coding	protein_coding	11.0016	7.438229	15.86061	1.769418	0.7499474	1.091389	1.1765385	0.0000000	2.255332	0.0000000	0.09597777	7.8235786	0.07109583	0.00000000	0.1430000	0.14300000	3.691241e-14	3.691241e-14	FALSE	TRUE
ENST00000649817	ENSG00000083168	HEK293_OSMI2_6hA	HEK293_TMG_6hB	KAT6A	protein_coding	protein_coding	11.0016	7.438229	15.86061	1.769418	0.7499474	1.091389	0.1419281	0.3482454	0.000000	0.1863098	0.00000000	-5.1628764	0.02428333	0.06946667	0.0000000	-0.06946667	2.290615e-01	3.691241e-14	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 47
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000083168	E001	229.5078820	1.2311346413	0.1722887019	0.393563427	8	41929479	41930760	1282	-	1.994	2.667	2.249
ENSG00000083168	E002	5.4862935	0.0097447498	0.0056746863	0.038114707	8	41930761	41930761	1	-	0.557	1.062	2.018
ENSG00000083168	E003	525.0055065	1.6620555485	0.3867831300	0.617944361	8	41930762	41933187	2426	-	2.505	2.932	1.421
ENSG00000083168	E004	285.6478422	1.4905918554	0.4678133710	0.678580623	8	41933188	41934399	1212	-	2.301	2.614	1.044
ENSG00000083168	E005	99.7408239	1.1061536017	0.4425646162	0.660436159	8	41934400	41934558	159	-	1.859	2.147	0.969
ENSG00000083168	E006	104.1912017	1.1355968952	0.4785506090	0.686109671	8	41934559	41934773	215	-	1.891	2.151	0.873
ENSG00000083168	E007	33.6777888	0.5101412168	0.3556810544	0.592265837	8	41934774	41934788	15	-	1.410	1.670	0.890
ENSG00000083168	E008	66.1613233	0.7672817817	0.5332734452	0.724398631	8	41934789	41934867	79	-	1.735	1.905	0.573
ENSG00000083168	E009	0.1779838	0.1250007502	0.7124909636		8	41934868	41937255	2388	-	0.086	0.000	-10.109
ENSG00000083168	E010	151.4275007	0.0009820756	0.0151530068	0.078660212	8	41937256	41937568	313	-	2.126	2.216	0.302
ENSG00000083168	E011	0.4820342	0.0220907217	0.1743109847		8	41938345	41940841	2497	-	0.218	0.000	-11.688
ENSG00000083168	E012	237.3640779	0.0442901698	0.1289186014	0.330091875	8	41940842	41941444	603	-	2.337	2.365	0.096
ENSG00000083168	E013	0.8026527	0.0177578464	0.0500816486		8	41941445	41942048	604	-	0.320	0.000	-12.425
ENSG00000083168	E014	0.5233527	0.0228595997	0.8387354788		8	41942049	41942786	738	-	0.157	0.170	0.142
ENSG00000083168	E015	0.7802874	0.0176630512	1.0000000000		8	41942787	41942792	6	-	0.218	0.292	0.556
ENSG00000083168	E016	122.0163121	0.0388464176	0.1888791812	0.415558074	8	41942793	41943000	208	-	2.046	2.085	0.128
ENSG00000083168	E017	1.4927703	0.0584612045	0.7317081946	0.855290503	8	41943001	41943747	747	-	0.362	0.389	0.152
ENSG00000083168	E018	107.5976141	0.0326157338	0.0249689884	0.112130012	8	41943748	41943979	232	-	2.016	1.985	-0.106
ENSG00000083168	E019	1.7227416	0.3665605052	0.6386506918	0.796118242	8	41943980	41944860	881	-	0.434	0.386	-0.265
ENSG00000083168	E020	0.1426347	0.0316214374	0.7133757304		8	41946513	41946590	78	-	0.085	0.000	-10.101
ENSG00000083168	E021	58.8070136	0.0287121523	0.0084552663	0.051403470	8	41946591	41946684	94	-	1.764	1.716	-0.161
ENSG00000083168	E022	2.6011386	0.0158198974	0.0177391930	0.088134430	8	41946685	41947750	1066	-	0.607	0.292	-1.669
ENSG00000083168	E023	73.4409558	0.0336658133	0.0277828333	0.120659901	8	41947751	41947912	162	-	1.846	1.835	-0.037
ENSG00000083168	E024	54.2581185	0.0234229568	0.1993740471	0.428949854	8	41949222	41949363	142	-	1.687	1.760	0.248
ENSG00000083168	E025	48.8012055	0.0240143842	0.1913151245	0.418525401	8	41955296	41955411	116	-	1.645	1.704	0.198
ENSG00000083168	E026	0.1426347	0.0316214374	0.7133757304		8	41957049	41957180	132	-	0.085	0.000	-10.101
ENSG00000083168	E027	0.7844689	0.1298094392	0.1009452381		8	41957181	41958363	1183	-	0.086	0.462	3.119
ENSG00000083168	E028	0.3393995	0.0287716239	0.3444642807		8	41964351	41964624	274	-	0.157	0.000	-11.105
ENSG00000083168	E029	0.0000000				8	41973404	41973421	18	-
ENSG00000083168	E030	0.0000000				8	41973422	41973497	76	-
ENSG00000083168	E031	1.6639769	0.4795207707	0.9819256370	0.992752067	8	41973498	41974703	1206	-	0.370	0.465	0.513
ENSG00000083168	E032	57.7812892	0.0198877742	0.0191279462	0.092892711	8	41974704	41974799	96	-	1.742	1.729	-0.044
ENSG00000083168	E033	41.8901014	0.0102890385	0.0158080902	0.081117308	8	41974800	41974822	23	-	1.603	1.596	-0.023
ENSG00000083168	E034	118.4376714	0.0326559575	0.0041872339	0.030198693	8	41977008	41977327	320	-	2.068	1.999	-0.228
ENSG00000083168	E035	0.0000000				8	41977328	41977490	163	-
ENSG00000083168	E036	0.3206185	0.0262094776	0.3452463950		8	41978621	41978641	21	-	0.157	0.000	-11.103
ENSG00000083168	E037	41.9234704	0.0747259260	0.0440193472	0.165145973	8	41978642	41978662	21	-	1.634	1.530	-0.356
ENSG00000083168	E038	72.8259474	0.0597382792	0.0206701531	0.098247973	8	41978663	41978777	115	-	1.865	1.775	-0.303
ENSG00000083168	E039	61.4504551	0.0393465668	0.0121128708	0.066915327	8	41980846	41980927	82	-	1.787	1.716	-0.238
ENSG00000083168	E040	72.0215816	0.0175002183	0.0024081769	0.019735731	8	41981839	41981954	116	-	1.850	1.794	-0.191
ENSG00000083168	E041	66.7359319	0.0149896988	0.0005117858	0.005784559	8	41987455	41987563	109	-	1.829	1.739	-0.302
ENSG00000083168	E042	0.6730019	0.0193874923	0.6936619861		8	42045878	42048377	2500	-	0.157	0.292	1.138
ENSG00000083168	E043	237.6979065	0.0287762244	0.0003539910	0.004276665	8	42048378	42049302	925	-	2.380	2.266	-0.382
ENSG00000083168	E044	0.0000000				8	42049303	42049575	273	-
ENSG00000083168	E045	20.3396227	0.0537361793	0.1060776276	0.292479883	8	42049576	42049619	44	-	1.310	1.266	-0.153
ENSG00000083168	E046	25.2404058	0.0359828122	0.0025536720	0.020679617	8	42049620	42049707	88	-	1.440	1.250	-0.663
ENSG00000083168	E047	27.7044169	0.0039361946	0.0002167459	0.002860175	8	42051901	42051994	94	-	1.466	1.344	-0.422

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000083168

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3