ENSG00000082014

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262188 ENSG00000082014 HEK293_OSMI2_6hA HEK293_TMG_6hB SMARCD3 protein_coding protein_coding 28.50053 39.48169 11.78704 2.99143 0.1644796 -1.743124 2.098332 1.695145 1.2836452 0.8734310 1.17362904 -0.3984526 0.06137083 0.03983333 0.10630000 0.06646667 1.0000000000 0.0001924512 FALSE TRUE
ENST00000356800 ENSG00000082014 HEK293_OSMI2_6hA HEK293_TMG_6hB SMARCD3 protein_coding protein_coding 28.50053 39.48169 11.78704 2.99143 0.1644796 -1.743124 16.097591 21.972747 5.2688073 4.2929607 1.40540853 -2.0580878 0.53968333 0.54606667 0.45020000 -0.09586667 0.8731087867 0.0001924512 FALSE TRUE
ENST00000392811 ENSG00000082014 HEK293_OSMI2_6hA HEK293_TMG_6hB SMARCD3 protein_coding protein_coding 28.50053 39.48169 11.78704 2.99143 0.1644796 -1.743124 2.608200 5.062918 0.2807357 0.7845879 0.08773733 -4.1250357 0.07930417 0.12660000 0.02386667 -0.10273333 0.0001924512 0.0001924512 FALSE TRUE
ENST00000470588 ENSG00000082014 HEK293_OSMI2_6hA HEK293_TMG_6hB SMARCD3 protein_coding retained_intron 28.50053 39.48169 11.78704 2.99143 0.1644796 -1.743124 1.996584 2.681964 1.4733137 0.7771147 0.17607982 -0.8598352 0.08672083 0.07183333 0.12520000 0.05336667 0.5298207837 0.0001924512 FALSE TRUE
ENST00000485610 ENSG00000082014 HEK293_OSMI2_6hA HEK293_TMG_6hB SMARCD3 protein_coding retained_intron 28.50053 39.48169 11.78704 2.99143 0.1644796 -1.743124 1.562885 2.108232 1.0352536 1.0010090 0.21503513 -1.0190076 0.06963333 0.05820000 0.08746667 0.02926667 0.7269226063 0.0001924512 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000082014 E001 0.0000000       7 151238764 151238779 16 -      
ENSG00000082014 E002 0.2735028 0.0258550350 0.2312851454   7 151238780 151238972 193 - 0.230 0.060 -2.237
ENSG00000082014 E003 0.2617363 0.1403646061 1.0000000000   7 151238973 151238973 1 - 0.000 0.111 9.854
ENSG00000082014 E004 0.8699390 0.0954865805 0.4564340984   7 151238974 151238975 2 - 0.000 0.243 11.334
ENSG00000082014 E005 1.9119627 0.0719026989 0.4692432486 0.67955342 7 151238976 151238980 5 - 0.490 0.368 -0.649
ENSG00000082014 E006 13.0277137 0.0325159886 0.4164497887 0.64100527 7 151238981 151239005 25 - 0.901 1.052 0.563
ENSG00000082014 E007 14.0708349 0.0493119724 0.6034464848 0.77248264 7 151239006 151239007 2 - 0.969 1.078 0.398
ENSG00000082014 E008 20.2805813 0.0342478508 0.2010837620 0.43105264 7 151239008 151239017 10 - 1.030 1.239 0.748
ENSG00000082014 E009 36.5115241 0.0276295876 0.0312394556 0.13103735 7 151239018 151239050 33 - 1.211 1.495 0.990
ENSG00000082014 E010 41.0824189 0.0683592103 0.1459148173 0.35624503 7 151239051 151239062 12 - 1.319 1.538 0.756
ENSG00000082014 E011 119.5391625 0.3844220005 0.1956660969 0.42418083 7 151239063 151239156 94 - 1.732 1.995 0.885
ENSG00000082014 E012 4.0970565 0.2699045009 0.5966620195 0.76808874 7 151239157 151239395 239 - 0.726 0.580 -0.623
ENSG00000082014 E013 167.8811209 0.1241419090 0.1401253317 0.34770386 7 151239396 151239497 102 - 1.922 2.136 0.720
ENSG00000082014 E014 7.9932362 0.0079946030 0.0034656908 0.02613688 7 151239498 151239623 126 - 1.110 0.771 -1.279
ENSG00000082014 E015 216.9142188 0.8917366175 0.3961426707 0.62525919 7 151239624 151239746 123 - 2.053 2.244 0.639
ENSG00000082014 E016 256.5119580 1.0117146298 0.4715969154 0.68127533 7 151240112 151240247 136 - 2.171 2.310 0.465
ENSG00000082014 E017 22.0292986 0.2425332584 0.7751632509 0.88181875 7 151240248 151240421 174 - 1.346 1.224 -0.426
ENSG00000082014 E018 6.0799021 0.2302105175 0.3027586171 0.54334680 7 151240422 151240424 3 - 0.971 0.685 -1.118
ENSG00000082014 E019 189.2523824 0.8859870031 0.4263171730 0.64826702 7 151240425 151240522 98 - 2.015 2.182 0.558
ENSG00000082014 E020 38.8544479 0.4327424764 0.9584745534 0.98111975 7 151240523 151240899 377 - 1.503 1.477 -0.089
ENSG00000082014 E021 33.8930131 0.1278323726 0.0730755072 0.23095672 7 151240900 151241163 264 - 1.614 1.372 -0.830
ENSG00000082014 E022 26.3645955 0.1750275122 0.0894224368 0.26271969 7 151241164 151241257 94 - 1.524 1.263 -0.906
ENSG00000082014 E023 32.0284631 0.1254419965 0.0726316728 0.23006600 7 151241258 151241394 137 - 1.584 1.350 -0.805
ENSG00000082014 E024 23.0669573 0.1598310726 0.0181502006 0.08952690 7 151241395 151241491 97 - 1.561 1.165 -1.377
ENSG00000082014 E025 210.5135479 0.0004537405 0.0141351199 0.07489528 7 151241492 151241653 162 - 2.239 2.201 -0.125
ENSG00000082014 E026 21.1753209 0.3185255180 0.1502576179 0.36266628 7 151241654 151241798 145 - 1.426 1.173 -0.884
ENSG00000082014 E027 12.6505503 0.2651175643 0.2153808628 0.44792670 7 151241799 151241876 78 - 1.160 0.985 -0.636
ENSG00000082014 E028 87.0960883 0.0012986575 0.0875976588 0.25926031 7 151241877 151241907 31 - 1.860 1.813 -0.158
ENSG00000082014 E029 87.9572181 0.0006814039 0.0179313593 0.08881635 7 151241908 151241936 29 - 1.888 1.814 -0.250
ENSG00000082014 E030 109.2718499 0.0006076707 0.0262421970 0.11605070 7 151241937 151241957 21 - 1.967 1.910 -0.193
ENSG00000082014 E031 118.8259400 0.0005011393 0.0082946191 0.05068062 7 151241958 151241978 21 - 2.014 1.944 -0.234
ENSG00000082014 E032 186.4505743 0.0140932698 0.1802878916 0.40440411 7 151242137 151242232 96 - 2.177 2.145 -0.105
ENSG00000082014 E033 1.9980542 0.9552167230 0.3641128167 0.59911569 7 151242233 151242464 232 - 0.482 0.380 -0.538
ENSG00000082014 E034 3.0154295 0.1480118266 0.9487708546 0.97660750 7 151242465 151242480 16 - 0.490 0.515 0.123
ENSG00000082014 E035 220.1743936 0.0373970038 0.4578302272 0.67162788 7 151242481 151242603 123 - 2.230 2.221 -0.031
ENSG00000082014 E036 0.8618718 1.3087196470 1.0000000000   7 151242705 151242720 16 - 0.000 0.250 10.421
ENSG00000082014 E037 164.6078906 0.0410489023 0.4425684115 0.66043616 7 151242721 151242843 123 - 2.112 2.094 -0.060
ENSG00000082014 E038 69.4529304 0.0453520153 0.8263737331 0.91171905 7 151243659 151243701 43 - 1.695 1.733 0.129
ENSG00000082014 E039 103.7518394 0.0125825446 0.0315509233 0.13192201 7 151245460 151245671 212 - 1.717 1.930 0.716
ENSG00000082014 E040 6.7791414 0.1583195735 0.2658016990 0.50523665 7 151245978 151246149 172 - 0.937 0.749 -0.732
ENSG00000082014 E041 20.3299994 0.0029736595 0.0134260935 0.07210358 7 151248485 151248694 210 - 0.939 1.264 1.173
ENSG00000082014 E042 1.0121411 0.0357927279 1.0000000000   7 151254295 151254478 184 - 0.231 0.242 0.090
ENSG00000082014 E043 54.1717562 0.0008152587 0.0005266085 0.00592018 7 151275114 151275251 138 - 1.369 1.661 1.001
ENSG00000082014 E044 0.5363366 0.0404305280 0.9274406046   7 151275252 151275252 1 - 0.000 0.161 10.897
ENSG00000082014 E045 0.0000000       7 151276705 151276734 30 -      
ENSG00000082014 E046 30.1749118 0.0021647141 0.0056069746 0.03776717 7 151277077 151277452 376 - 1.111 1.421 1.091
ENSG00000082014 E047 0.0000000       7 151277800 151277896 97 -