ENSG00000080823

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000518686 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding retained_intron 11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 2.1636718 2.7219227 2.0372571 0.4643884 0.20979395 -0.4162244 0.196287500 0.21830000 0.25410000 0.03580000 0.897128958 0.003963124 TRUE  
ENST00000519058 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding protein_coding 11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 0.9023641 1.6461539 0.5550758 0.4986571 0.08262907 -1.5513205 0.082616667 0.13123333 0.06903333 -0.06220000 0.501293918 0.003963124 FALSE  
ENST00000521937 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding protein_coding 11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 1.9507221 2.2572576 0.8134957 0.4234938 0.55355844 -1.4611152 0.166779167 0.18486667 0.09283333 -0.09203333 0.697137963 0.003963124 FALSE  
ENST00000522534 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding protein_coding 11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 0.0581939 0.0000000 0.4655512 0.0000000 0.46555122 5.5715288 0.007816667 0.00000000 0.06253333 0.06253333 0.851768306 0.003963124 FALSE  
ENST00000522874 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding protein_coding 11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 0.8733761 0.9115977 0.0000000 0.3397191 0.00000000 -6.5260651 0.078604167 0.07926667 0.00000000 -0.07926667 0.003963124 0.003963124 FALSE  
MSTRG.10203.23 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding   11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 0.8273739 1.1243843 0.2522730 0.5706454 0.25227301 -2.1127682 0.077600000 0.09923333 0.02796667 -0.07126667 0.723327341 0.003963124 TRUE  
MSTRG.10203.35 ENSG00000080823 HEK293_OSMI2_6hA HEK293_TMG_6hB MOK protein_coding   11.05017 12.29629 8.158591 1.115392 0.4625373 -0.5912373 0.1395452 0.0000000 0.9547306 0.0000000 0.53289843 6.5920543 0.015229167 0.00000000 0.11060000 0.11060000 0.214870950 0.003963124 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000080823 E001 1.8437959 0.0711369683 0.944924216 0.97476000 14 102224500 102224655 156 - 0.455 0.444 -0.053
ENSG00000080823 E002 2.9688319 0.0819475700 0.760152111 0.87262774 14 102224656 102224794 139 - 0.625 0.566 -0.264
ENSG00000080823 E003 2.8132159 0.0084553339 0.096998715 0.27650210 14 102225095 102225219 125 - 0.715 0.446 -1.227
ENSG00000080823 E004 10.5777569 0.0045042475 0.002895249 0.02277244 14 102225220 102225945 726 - 1.225 0.912 -1.141
ENSG00000080823 E005 1.9345858 0.1464898751 0.257359212 0.49610109 14 102225946 102226139 194 - 0.623 0.365 -1.281
ENSG00000080823 E006 4.3176122 0.0061975864 0.402903700 0.63068193 14 102226140 102226408 269 - 0.787 0.661 -0.516
ENSG00000080823 E007 0.2027342 0.0499570151 1.000000000   14 102228827 102228830 4 - 0.000 0.088 11.359
ENSG00000080823 E008 0.1779838 0.0335122362 0.244112476   14 102228831 102228835 5 - 0.166 0.000 -13.728
ENSG00000080823 E009 0.3503582 0.0263123111 0.601853403   14 102228836 102228838 3 - 0.166 0.088 -1.056
ENSG00000080823 E010 12.2933445 0.0312497312 0.792429624 0.89186446 14 102228839 102228885 47 - 1.086 1.100 0.051
ENSG00000080823 E011 24.4850141 0.0081753406 0.783121086 0.88648904 14 102228886 102228989 104 - 1.369 1.380 0.039
ENSG00000080823 E012 18.6165187 0.0258102866 0.761404700 0.87344572 14 102228990 102228992 3 - 1.252 1.266 0.051
ENSG00000080823 E013 27.6060408 0.0020036437 0.111893771 0.30225208 14 102228993 102229072 80 - 1.350 1.459 0.374
ENSG00000080823 E014 20.1118836 0.0038724156 0.042797404 0.16202751 14 102229073 102229119 47 - 1.175 1.347 0.606
ENSG00000080823 E015 12.9319578 0.0044616971 0.038618025 0.15116003 14 102229120 102229123 4 - 0.972 1.184 0.771
ENSG00000080823 E016 14.3314066 0.0026383642 0.030015810 0.12738979 14 102229124 102229136 13 - 1.013 1.221 0.751
ENSG00000080823 E017 15.3832212 0.0026386321 0.032080020 0.13345158 14 102229137 102229159 23 - 1.050 1.249 0.712
ENSG00000080823 E018 16.3775614 0.0160525579 0.028258533 0.12205038 14 102229160 102229185 26 - 1.049 1.280 0.824
ENSG00000080823 E019 26.4696571 0.0015245150 0.010796141 0.06151267 14 102229186 102229208 23 - 1.282 1.465 0.635
ENSG00000080823 E020 25.3956962 0.0015371387 0.064357688 0.21247677 14 102229209 102229213 5 - 1.303 1.434 0.456
ENSG00000080823 E021 41.2084837 0.0009514044 0.107689920 0.29520468 14 102229214 102229266 53 - 1.538 1.625 0.297
ENSG00000080823 E022 52.6914836 0.0007572053 0.088051836 0.26011041 14 102229267 102229362 96 - 1.646 1.727 0.274
ENSG00000080823 E023 26.7102714 0.0015577177 0.058231218 0.19878371 14 102229363 102229366 4 - 1.322 1.455 0.459
ENSG00000080823 E024 22.4237389 0.0024061997 0.012228026 0.06735647 14 102229367 102229432 66 - 1.188 1.390 0.705
ENSG00000080823 E025 14.0015895 0.0099879199 0.060979594 0.20496670 14 102229433 102229438 6 - 0.993 1.194 0.725
ENSG00000080823 E026 15.7684598 0.0079459517 0.057817808 0.19792363 14 102229439 102229456 18 - 1.051 1.241 0.680
ENSG00000080823 E027 64.2923740 0.0023987746 0.279044643 0.51913498 14 102229457 102229577 121 - 1.751 1.801 0.167
ENSG00000080823 E028 43.8046281 0.0009751527 0.791703260 0.89143846 14 102229578 102229619 42 - 1.618 1.625 0.024
ENSG00000080823 E029 42.7257818 0.0039107394 0.715425254 0.84517322 14 102229620 102229651 32 - 1.628 1.599 -0.097
ENSG00000080823 E030 33.3724314 0.0022029005 0.993216960 0.99828011 14 102229652 102229657 6 - 1.508 1.501 -0.024
ENSG00000080823 E031 23.4261217 0.0019117549 0.630105422 0.79044496 14 102229658 102231706 2049 - 1.385 1.339 -0.160
ENSG00000080823 E032 24.6778723 0.0059541823 0.709649103 0.84160101 14 102231707 102231745 39 - 1.360 1.386 0.089
ENSG00000080823 E033 27.2230054 0.0159208186 0.631425880 0.79130578 14 102231746 102231821 76 - 1.395 1.431 0.126
ENSG00000080823 E034 3.5549745 0.1411672239 0.747763326 0.86534277 14 102231822 102232534 713 - 0.577 0.650 0.320
ENSG00000080823 E035 37.2839195 0.0010939686 0.240063291 0.47668952 14 102232535 102232552 18 - 1.603 1.524 -0.268
ENSG00000080823 E036 59.5501411 0.0008529623 0.368236750 0.60258503 14 102232553 102232671 119 - 1.786 1.734 -0.173
ENSG00000080823 E037 28.1459133 0.0019012357 0.089975973 0.26373912 14 102232672 102232708 37 - 1.520 1.396 -0.425
ENSG00000080823 E038 71.3937828 0.0097370827 0.854211611 0.92719810 14 102232709 102233338 630 - 1.838 1.826 -0.040
ENSG00000080823 E039 39.2142840 0.0362684809 0.917343944 0.96089622 14 102233339 102233463 125 - 1.577 1.573 -0.015
ENSG00000080823 E040 40.3558673 0.0306422745 0.785135691 0.88763623 14 102233464 102233687 224 - 1.591 1.584 -0.023
ENSG00000080823 E041 33.5923163 0.0216902845 0.159625576 0.37623481 14 102233688 102233760 73 - 1.606 1.460 -0.503
ENSG00000080823 E042 21.5832622 0.0444510577 0.564041443 0.74614991 14 102233761 102233789 29 - 1.390 1.292 -0.341
ENSG00000080823 E043 0.8507255 0.0183633839 0.093252646   14 102233790 102233809 20 - 0.000 0.326 13.603
ENSG00000080823 E044 1.4386171 0.1432857223 0.226422663 0.46112988 14 102233810 102234153 344 - 0.165 0.446 1.954
ENSG00000080823 E045 0.1723744 0.0304004556 1.000000000   14 102234957 102235063 107 - 0.000 0.088 11.389
ENSG00000080823 E046 2.3516780 0.0663516527 0.867436202 0.93454348 14 102235365 102235401 37 - 0.520 0.484 -0.176
ENSG00000080823 E047 1.7738351 0.0312843422 0.410885148 0.63671982 14 102235402 102235569 168 - 0.521 0.371 -0.784
ENSG00000080823 E048 0.5474829 0.0285404986 0.261241783   14 102238022 102238317 296 - 0.000 0.224 12.907
ENSG00000080823 E049 0.3751086 0.0244768415 0.465745539   14 102238318 102238364 47 - 0.000 0.161 12.361
ENSG00000080823 E050 0.2027342 0.0499570151 1.000000000   14 102238365 102238446 82 - 0.000 0.088 11.359
ENSG00000080823 E051 0.5778428 0.1993974908 0.283138653   14 102240452 102240621 170 - 0.000 0.228 12.678
ENSG00000080823 E052 0.2027342 0.0499570151 1.000000000   14 102246057 102246247 191 - 0.000 0.088 11.359
ENSG00000080823 E053 0.0000000       14 102247395 102247464 70 -      
ENSG00000080823 E054 16.5035830 0.0635773927 0.224238891 0.45846381 14 102250812 102250837 26 - 1.345 1.140 -0.722
ENSG00000080823 E055 22.4055951 0.0432312198 0.096816662 0.27614074 14 102250838 102250894 57 - 1.479 1.254 -0.779
ENSG00000080823 E056 22.1168391 0.0356831539 0.737070110 0.85863463 14 102250895 102250966 72 - 1.375 1.315 -0.208
ENSG00000080823 E057 15.6239664 0.0978080863 0.747392924 0.86513877 14 102250967 102250987 21 - 1.181 1.199 0.065
ENSG00000080823 E058 7.7159893 0.1248291779 0.873660021 0.93799631 14 102250988 102250990 3 - 0.946 0.904 -0.156
ENSG00000080823 E059 1.5725786 0.0139904561 0.274971497 0.51497038 14 102251444 102251466 23 - 0.522 0.326 -1.059
ENSG00000080823 E060 1.6685749 0.0739415135 0.837791268 0.91819984 14 102251467 102251504 38 - 0.380 0.411 0.173
ENSG00000080823 E061 2.6506688 0.2348797031 0.687883463 0.82774223 14 102251505 102251610 106 - 0.578 0.499 -0.370
ENSG00000080823 E062 0.8094069 0.0193874923 0.534624575   14 102251611 102251742 132 - 0.166 0.278 0.944
ENSG00000080823 E063 0.1723744 0.0304004556 1.000000000   14 102251743 102251755 13 - 0.000 0.088 11.389
ENSG00000080823 E064 18.8051791 0.0626817474 0.642531745 0.79856355 14 102251756 102251804 49 - 1.328 1.241 -0.305
ENSG00000080823 E065 0.3337900 0.0261217753 0.601598707   14 102251805 102251916 112 - 0.166 0.088 -1.055
ENSG00000080823 E066 20.1668996 0.0065644172 0.306150124 0.54681096 14 102251917 102251960 44 - 1.367 1.270 -0.341
ENSG00000080823 E067 20.3736800 0.0119016081 0.788436771 0.88961172 14 102251961 102251995 35 - 1.331 1.291 -0.140
ENSG00000080823 E068 0.1308682 0.0311965842 1.000000000   14 102260591 102260672 82 - 0.000 0.088 11.384
ENSG00000080823 E069 0.2027342 0.0499570151 1.000000000   14 102263537 102263545 9 - 0.000 0.088 11.359
ENSG00000080823 E070 18.0133967 0.0228920279 0.257086884 0.49589187 14 102263546 102263616 71 - 1.341 1.202 -0.487
ENSG00000080823 E071 0.6544085 0.0188319846 0.089171014   14 102263617 102264651 1035 - 0.379 0.088 -2.641
ENSG00000080823 E072 15.6980768 0.0188637932 0.532923153 0.72412558 14 102265823 102265912 90 - 1.249 1.166 -0.294
ENSG00000080823 E073 0.1308682 0.0311965842 1.000000000   14 102277299 102277450 152 - 0.000 0.088 11.384
ENSG00000080823 E074 2.0882966 0.0094409875 0.127908808 0.32851180 14 102278606 102278694 89 - 0.629 0.370 -1.278
ENSG00000080823 E075 0.6182515 0.0205620226 0.742425800   14 102280674 102280824 151 - 0.166 0.223 0.529
ENSG00000080823 E076 0.0000000       14 102283131 102283477 347 -      
ENSG00000080823 E077 40.9048357 0.0086760428 0.038998441 0.15217905 14 102283478 102283592 115 - 1.697 1.538 -0.541
ENSG00000080823 E078 38.9489318 0.0054186919 0.002181748 0.01828420 14 102304962 102305190 229 - 1.706 1.496 -0.717