ENSG00000079215

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265113 ENSG00000079215 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC1A3 protein_coding protein_coding 13.55123 6.419366 31.93638 1.789208 0.4448498 2.312904 10.2667232 3.6945503 27.03066564 0.9363654 0.69523980 2.867760 0.65677917 0.58933333 0.846133333 0.25680000 2.168168e-05 2.168168e-05 FALSE TRUE
ENST00000506178 ENSG00000079215 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC1A3 protein_coding retained_intron 13.55123 6.419366 31.93638 1.789208 0.4448498 2.312904 0.3355040 0.7855648 0.09716353 0.6970613 0.09716353 -2.892165 0.05715417 0.10326667 0.002966667 -0.10030000 4.737897e-01 2.168168e-05 FALSE TRUE
ENST00000681440 ENSG00000079215 HEK293_OSMI2_6hA HEK293_TMG_6hB SLC1A3 protein_coding protein_coding 13.55123 6.419366 31.93638 1.789208 0.4448498 2.312904 0.4804075 0.5670176 0.10746197 0.5670176 0.10746197 -2.296422 0.07855833 0.07496667 0.003300000 -0.07166667 8.742643e-01 2.168168e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000079215 E001 0.0000000       5 36596588 36596678 91 +      
ENSG00000079215 E002 0.0000000       5 36606355 36606438 84 +      
ENSG00000079215 E003 0.0000000       5 36606439 36606464 26 +      
ENSG00000079215 E004 0.0000000       5 36606465 36606530 66 +      
ENSG00000079215 E005 1.0103762 0.0178182867 1.000000e+00   5 36606531 36606595 65 + 0.234 0.238 0.036
ENSG00000079215 E006 1.3309947 0.0304778844 7.462191e-01   5 36606596 36606605 10 + 0.301 0.238 -0.450
ENSG00000079215 E007 1.3309947 0.0304778844 7.462191e-01   5 36606606 36606606 1 + 0.301 0.238 -0.450
ENSG00000079215 E008 1.6232785 0.0119038447 8.185924e-01 9.072304e-01 5 36606607 36606610 4 + 0.331 0.391 0.357
ENSG00000079215 E009 3.8732511 0.0071759946 6.534858e-01 8.057570e-01 5 36606611 36606616 6 + 0.569 0.668 0.431
ENSG00000079215 E010 10.5333289 0.0246253726 4.771630e-01 6.850853e-01 5 36606617 36606622 6 + 0.962 0.877 -0.319
ENSG00000079215 E011 23.3470612 0.0017535942 6.232563e-01 7.860679e-01 5 36606623 36606629 7 + 1.271 1.250 -0.072
ENSG00000079215 E012 25.9975986 0.0022601538 3.897692e-01 6.202901e-01 5 36606630 36606631 2 + 1.321 1.268 -0.185
ENSG00000079215 E013 70.0554058 0.0007003205 4.190775e-02 1.596971e-01 5 36606632 36606735 104 + 1.742 1.651 -0.308
ENSG00000079215 E014 0.1426347 0.0327379577 1.000000e+00   5 36606736 36606889 154 + 0.058 0.000 -11.640
ENSG00000079215 E015 0.3453689 0.0269817872 2.483265e-01   5 36606890 36606994 105 + 0.058 0.239 2.364
ENSG00000079215 E016 0.2027342 0.0321818496 8.015182e-02   5 36606995 36607014 20 + 0.000 0.239 13.663
ENSG00000079215 E017 0.0000000       5 36607015 36607172 158 +      
ENSG00000079215 E018 0.6896403 0.4834696794 3.498635e-01   5 36607173 36607223 51 + 0.150 0.378 1.752
ENSG00000079215 E019 6.2411781 0.0051886747 9.673198e-01 9.856192e-01 5 36607224 36607311 88 + 0.756 0.786 0.119
ENSG00000079215 E020 0.0000000       5 36607331 36607452 122 +      
ENSG00000079215 E021 0.0000000       5 36608146 36608177 32 +      
ENSG00000079215 E022 0.0000000       5 36608178 36608193 16 +      
ENSG00000079215 E023 0.1426347 0.0327379577 1.000000e+00   5 36608194 36608328 135 + 0.058 0.000 -11.640
ENSG00000079215 E024 178.4776678 0.0003923317 9.683111e-03 5.676269e-02 5 36608329 36608600 272 + 2.138 2.072 -0.222
ENSG00000079215 E025 64.6086408 0.0138354967 9.432719e-01 9.739757e-01 5 36608601 36608604 4 + 1.688 1.695 0.024
ENSG00000079215 E026 4.2644115 0.1473386950 1.998249e-02 9.581246e-02 5 36608605 36609177 573 + 0.498 0.982 2.002
ENSG00000079215 E027 0.6260739 0.1223466562 1.493739e-01   5 36609178 36609299 122 + 0.109 0.390 2.350
ENSG00000079215 E028 0.2852693 0.3272829316 1.000000e+00   5 36609349 36609378 30 + 0.107 0.000 -11.856
ENSG00000079215 E029 0.0000000       5 36611552 36611783 232 +      
ENSG00000079215 E030 0.7310763 0.2114076565 1.550285e-01   5 36612746 36612809 64 + 0.110 0.396 2.367
ENSG00000079215 E031 0.9394200 0.7174028515 3.848290e-01   5 36612810 36613055 246 + 0.161 0.411 1.815
ENSG00000079215 E032 0.3807181 0.0292766131 2.494627e-01   5 36613056 36613098 43 + 0.058 0.239 2.361
ENSG00000079215 E033 0.5834523 0.2525263752 9.258355e-02   5 36613099 36613299 201 + 0.058 0.400 3.395
ENSG00000079215 E034 0.1779838 0.0362465534 1.000000e+00   5 36613300 36613487 188 + 0.058 0.000 -11.612
ENSG00000079215 E035 0.5775531 0.0205581656 6.829608e-01   5 36614937 36614979 43 + 0.154 0.238 0.774
ENSG00000079215 E036 0.1723744 0.0784968098 8.201308e-02   5 36615091 36615111 21 + 0.000 0.239 13.338
ENSG00000079215 E037 138.2711567 0.0004812097 7.543971e-02 2.357333e-01 5 36629450 36629587 138 + 2.022 1.976 -0.154
ENSG00000079215 E038 0.1426347 0.0327379577 1.000000e+00   5 36629588 36629832 245 + 0.058 0.000 -11.640
ENSG00000079215 E039 0.0000000       5 36629833 36629942 110 +      
ENSG00000079215 E040 1.1721518 0.0253291892 1.157400e-01   5 36629943 36630044 102 + 0.196 0.505 1.950
ENSG00000079215 E041 0.1614157 0.0346562081 1.000000e+00   5 36630045 36630414 370 + 0.058 0.000 -11.625
ENSG00000079215 E042 0.6957271 0.0191017515 1.326162e-01   5 36630415 36630482 68 + 0.109 0.392 2.362
ENSG00000079215 E043 0.1426347 0.0327379577 1.000000e+00   5 36630483 36630500 18 + 0.058 0.000 -11.640
ENSG00000079215 E044 0.9716304 0.5354832657 4.451026e-01   5 36630501 36631401 901 + 0.195 0.397 1.398
ENSG00000079215 E045 0.0000000       5 36636151 36636300 150 +      
ENSG00000079215 E046 0.1426347 0.0327379577 1.000000e+00   5 36663757 36663888 132 + 0.058 0.000 -11.640
ENSG00000079215 E047 9.3870933 0.0625171430 2.992475e-07 9.837163e-06 5 36667717 36670820 3104 + 0.634 1.415 2.922
ENSG00000079215 E048 1.0902369 0.1360530773 1.067168e-01   5 36670821 36670903 83 + 0.155 0.512 2.398
ENSG00000079215 E049 1.5309525 0.0127863390 7.016717e-01 8.366568e-01 5 36670904 36671028 125 + 0.300 0.392 0.554
ENSG00000079215 E050 163.9124842 0.0002791263 1.906348e-02 9.269894e-02 5 36671029 36671233 205 + 2.098 2.038 -0.201
ENSG00000079215 E051 0.6731895 0.0562592896 6.741515e-01   5 36671234 36671383 150 + 0.155 0.239 0.773
ENSG00000079215 E052 4.5450897 0.0465349377 9.415339e-01 9.729901e-01 5 36671384 36674048 2665 + 0.643 0.668 0.105
ENSG00000079215 E053 75.8557408 0.0005498685 7.744478e-01 8.813937e-01 5 36674049 36674091 43 + 1.757 1.769 0.041
ENSG00000079215 E054 1.1539909 0.3443289191 5.214874e-01   5 36674092 36674518 427 + 0.229 0.403 1.134
ENSG00000079215 E055 9.2240260 0.0154506083 5.802508e-01 7.573412e-01 5 36674519 36676857 2339 + 0.902 0.836 -0.254
ENSG00000079215 E056 183.1653690 0.0002500885 2.394608e-03 1.965108e-02 5 36676892 36677184 293 + 2.149 2.069 -0.269
ENSG00000079215 E057 11.4990110 0.0028798330 4.211091e-01 6.444901e-01 5 36677185 36679349 2165 + 0.999 0.919 -0.297
ENSG00000079215 E058 2.2923568 0.0127387779 2.385701e-01 4.749727e-01 5 36679350 36679490 141 + 0.476 0.238 -1.447
ENSG00000079215 E059 0.7673035 0.0193874923 4.030602e-01   5 36679491 36679579 89 + 0.233 0.000 -14.021
ENSG00000079215 E060 0.9169527 0.0156973323 1.000000e+00   5 36679580 36679626 47 + 0.233 0.238 0.036
ENSG00000079215 E061 116.2828137 0.0003989381 2.483007e-01 4.860833e-01 5 36679627 36679754 128 + 1.945 1.922 -0.078
ENSG00000079215 E062 106.9865491 0.0003827761 5.042289e-01 7.037386e-01 5 36679755 36679860 106 + 1.896 1.951 0.188
ENSG00000079215 E063 1.6373599 0.2337171270 1.301700e-01 3.320872e-01 5 36680101 36680346 246 + 0.237 0.609 2.074
ENSG00000079215 E064 1.3689166 0.0256030964 1.761923e-01   5 36680347 36680394 48 + 0.234 0.505 1.625
ENSG00000079215 E065 137.6268645 0.0016631583 2.168069e-01 4.496511e-01 5 36680395 36680589 195 + 2.000 2.079 0.266
ENSG00000079215 E066 1.9864535 0.1901754818 5.084844e-01 7.068360e-01 5 36680590 36680885 296 + 0.377 0.506 0.671
ENSG00000079215 E067 2.6827796 0.2105320688 4.426261e-01 6.604526e-01 5 36683347 36683863 517 + 0.434 0.605 0.816
ENSG00000079215 E068 123.4611645 0.0021224281 7.609203e-01 8.731293e-01 5 36683864 36683998 135 + 1.966 1.981 0.052
ENSG00000079215 E069 973.4232564 0.0050609878 1.397501e-01 3.470975e-01 5 36686065 36688334 2270 + 2.848 2.918 0.233