ENSG00000078114

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000417816 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding protein_coding 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 0.46109495 0.0000000 0.49202420 0.0000000 0.10101098 5.649685 0.12797917 0.00000000 0.24440000 0.24440000 0.001661395 0.001661395 FALSE TRUE
ENST00000460652 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding nonsense_mediated_decay 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 0.08032604 0.2696771 0.05688362 0.1350543 0.05688362 -2.064037 0.04767083 0.14540000 0.02413333 -0.12126667 0.579042810 0.001661395 TRUE FALSE
ENST00000473616 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding protein_coding 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 0.10977993 0.2045951 0.04620628 0.2045951 0.04620628 -1.932814 0.04725833 0.08846667 0.02870000 -0.05976667 0.956028998 0.001661395 FALSE FALSE
ENST00000482754 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding retained_intron 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 0.02353073 0.1882459 0.00000000 0.1882459 0.00000000 -4.309219 0.01017500 0.08140000 0.00000000 -0.08140000 0.788859951 0.001661395   FALSE
ENST00000493005 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding retained_intron 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 0.05218486 0.1572734 0.00000000 0.0694364 0.00000000 -4.064136 0.02529583 0.08743333 0.00000000 -0.08743333 0.002972632 0.001661395 TRUE TRUE
ENST00000675700 ENSG00000078114 HEK293_OSMI2_6hA HEK293_TMG_6hB NEBL protein_coding processed_transcript 2.560019 1.639022 2.289426 0.3691751 0.3742498 0.4796626 1.48953810 0.6298625 1.41175101 0.1816149 0.43631618 1.151835 0.55989583 0.47023333 0.58243333 0.11220000 0.898052955 0.001661395 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000078114 E001 0.3040503 0.02600627 0.2881213634   10 20779973 20780049 77 -      
ENSG00000078114 E002 98.9173966 1.19409319 0.7025227345 0.837165942 10 20780050 20783905 3856 -      
ENSG00000078114 E003 42.3887665 0.46801368 0.9250392968 0.964820597 10 20783906 20785663 1758 -      
ENSG00000078114 E004 11.4242330 0.04335178 0.2207103493 0.454293277 10 20785664 20785923 260 -      
ENSG00000078114 E005 11.0836949 0.03430148 0.6950089001 0.832315719 10 20787202 20787308 107 -      
ENSG00000078114 E006 0.0000000       10 20793333 20793376 44 -      
ENSG00000078114 E007 0.0000000       10 20808510 20808659 150 -      
ENSG00000078114 E008 0.0000000       10 20809806 20809866 61 -      
ENSG00000078114 E009 0.0000000       10 20809867 20809898 32 -      
ENSG00000078114 E010 14.2279068 0.20214435 0.3200599897 0.559809128 10 20812769 20812940 172 -      
ENSG00000078114 E011 1.9676992 0.11932750 0.0198615916 0.095394396 10 20813740 20813938 199 -      
ENSG00000078114 E012 2.9660486 0.65600483 0.2346375777 0.470436792 10 20813939 20814043 105 -      
ENSG00000078114 E013 2.8483520 0.35314631 0.0498445508 0.179269583 10 20815625 20815717 93 -      
ENSG00000078114 E014 0.4458772 0.02176816 0.4359520503   10 20815718 20815825 108 -      
ENSG00000078114 E015 0.5117739 0.04928085 0.7371385718   10 20817598 20817599 2 -      
ENSG00000078114 E016 3.7085154 0.15073958 0.1127196068 0.303695616 10 20817600 20817692 93 -      
ENSG00000078114 E017 0.2852693 0.16382772 0.3246003449   10 20818318 20818703 386 -      
ENSG00000078114 E018 1.9234843 0.01136984 0.2789752399 0.519055821 10 20818704 20818834 131 -      
ENSG00000078114 E019 2.7250688 0.11403654 0.0821055301 0.248940520 10 20818835 20819423 589 -      
ENSG00000078114 E020 2.2112698 0.63211449 0.3523024325 0.589347413 10 20819424 20819516 93 -      
ENSG00000078114 E021 2.1163710 0.33864300 0.4954702683 0.697783699 10 20823208 20823300 93 -      
ENSG00000078114 E022 2.0692553 0.29531876 0.1888942283 0.415558074 10 20826447 20826539 93 -      
ENSG00000078114 E023 1.8789574 0.01180545 0.0267565429 0.117551705 10 20828530 20828634 105 -      
ENSG00000078114 E024 0.0000000       10 20831146 20831195 50 -      
ENSG00000078114 E025 2.3733553 0.01188051 0.0040973862 0.029713486 10 20831196 20831306 111 -      
ENSG00000078114 E026 2.0527368 0.01462281 0.0002225386 0.002921177 10 20831473 20831583 111 -      
ENSG00000078114 E027 1.7022587 0.08179107 0.0312278234 0.131001498 10 20835513 20835623 111 -      
ENSG00000078114 E028 1.8748207 0.41053397 0.3333578164 0.571948163 10 20840739 20840849 111 -      
ENSG00000078114 E029 1.8107770 0.61410431 0.5072695560 0.705854708 10 20845258 20845368 111 -      
ENSG00000078114 E030 0.4873834 0.25095269 0.5110479007   10 20845369 20845495 127 -      
ENSG00000078114 E031 1.2325589 0.02334159 0.0724868496   10 20850395 20850502 108 -      
ENSG00000078114 E032 1.9697922 0.03772061 0.1252231847 0.324133900 10 20852545 20852649 105 -      
ENSG00000078114 E033 1.8681864 0.01320243 0.2924240611 0.533135447 10 20858240 20858344 105 -      
ENSG00000078114 E034 0.0000000       10 20859283 20859712 430 -      
ENSG00000078114 E035 1.2145857 0.01403415 0.6776712940   10 20859713 20859826 114 -      
ENSG00000078114 E036 0.0000000       10 20867759 20868663 905 -      
ENSG00000078114 E037 1.1603853 0.01537876 0.4520002444   10 20868664 20868765 102 -      
ENSG00000078114 E038 0.7844689 0.03490144 0.1092950835   10 20869740 20869841 102 -      
ENSG00000078114 E039 0.9706349 0.01558838 0.0449262260   10 20880794 20880873 80 -      
ENSG00000078114 E040 1.0177506 0.01646679 0.2480047298   10 20880874 20880904 31 -      
ENSG00000078114 E041 1.3928592 0.03218140 0.0761909400 0.237120861 10 20888097 20888207 111 -      
ENSG00000078114 E042 0.9706349 0.01558838 0.0449262260   10 20889845 20889949 105 -      
ENSG00000078114 E043 0.6064850 0.02011119 0.0220129449   10 20896958 20897029 72 -      
ENSG00000078114 E044 0.0000000       10 20897125 20897311 187 -      
ENSG00000078114 E045 0.5059767 0.02176816 0.0562975651   10 20899378 20899450 73 -      
ENSG00000078114 E046 0.0000000       10 20899451 20899691 241 -      
ENSG00000078114 E047 0.3751086 0.04075893 0.1538652394   10 20945338 20945425 88 -      
ENSG00000078114 E048 0.8100271 0.01682205 0.4433386708   10 20957731 20957815 85 -      
ENSG00000078114 E049 0.8995767 0.01651316 0.7217324505   10 20958846 20958966 121 -      
ENSG00000078114 E050 0.7499275 0.01807869 0.9120474871   10 20959924 20959999 76 -      
ENSG00000078114 E051 0.4764247 0.02176816 0.7523912380   10 20960000 20960012 13 -      
ENSG00000078114 E052 3.3334068 0.24856181 0.2968886966 0.537357382 10 20960089 20961671 1583 -      
ENSG00000078114 E053 10.8377985 0.22333165 0.4339363203 0.654156956 10 20961672 20961779 108 -      
ENSG00000078114 E054 0.0000000       10 21002634 21002696 63 -      
ENSG00000078114 E055 8.4453496 0.19668499 0.1667232886 0.386167555 10 21020117 21020201 85 -      
ENSG00000078114 E056 0.0000000       10 21054224 21054278 55 -      
ENSG00000078114 E057 0.0000000       10 21054977 21055033 57 -      
ENSG00000078114 E058 0.1308682 0.03898681 0.4132612306   10 21100318 21100464 147 -      
ENSG00000078114 E059 0.0000000       10 21101018 21101130 113 -      
ENSG00000078114 E060 0.0000000       10 21125763 21126123 361 -      
ENSG00000078114 E061 0.0000000       10 21126124 21126158 35 -      
ENSG00000078114 E062 0.0000000       10 21126332 21126463 132 -      
ENSG00000078114 E063 0.1308682 0.03898681 0.4132612306   10 21146342 21146559 218 -      
ENSG00000078114 E064 0.5421338 0.07341781 0.7408484703   10 21170262 21170727 466 -      
ENSG00000078114 E065 0.3503582 0.33306388 0.9456616409   10 21171547 21172382 836 -      
ENSG00000078114 E066 6.7759508 0.07586300 0.0663667392 0.216888266 10 21172383 21172477 95 -      
ENSG00000078114 E067 4.5006803 0.11861685 0.0480164523 0.175024865 10 21173765 21174187 423 -      
ENSG00000078114 E068 0.0000000       10 21174840 21174931 92 -      
ENSG00000078114 E069 0.0000000       10 21247921 21247989 69 -      
ENSG00000078114 E070 0.1426347 0.03403423 0.5962421095   10 21251732 21251828 97 -      
ENSG00000078114 E071 0.1426347 0.03403423 0.5962421095   10 21292830 21293011 182 -