• ENSG00000073670
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000073670

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000200557 ENSG00000073670 HEK293_OSMI2_6hA HEK293_TMG_6hB ADAM11 protein_coding protein_coding 9.67068 13.37464 7.178537 1.264564 0.6102902 -0.8968085 1.3319831 1.6409182 1.1765889 0.25947915 0.47612310 -0.4764485 0.1434750 0.12126667 0.1561000 0.03483333 0.9241296664 0.0004257019 FALSE TRUE
ENST00000355638 ENSG00000073670 HEK293_OSMI2_6hA HEK293_TMG_6hB ADAM11 protein_coding nonsense_mediated_decay 9.67068 13.37464 7.178537 1.264564 0.6102902 -0.8968085 2.1944433 3.1031490 1.4653370 0.76180747 0.74245125 -1.0773301 0.2324458 0.23696667 0.2229333 -0.01403333 0.9569732104 0.0004257019 FALSE TRUE
ENST00000587773 ENSG00000073670 HEK293_OSMI2_6hA HEK293_TMG_6hB ADAM11 protein_coding nonsense_mediated_decay 9.67068 13.37464 7.178537 1.264564 0.6102902 -0.8968085 2.6836265 3.9451249 0.8296516 0.99673975 0.57740806 -2.2358606 0.2552667 0.29263333 0.1046333 -0.18800000 0.5694204222 0.0004257019 TRUE TRUE
ENST00000588363 ENSG00000073670 HEK293_OSMI2_6hA HEK293_TMG_6hB ADAM11 protein_coding retained_intron 9.67068 13.37464 7.178537 1.264564 0.6102902 -0.8968085 0.7682635 0.8283756 1.7822994 0.07525498 0.40446651 1.0961431 0.0839375 0.06203333 0.2444333 0.18240000 0.0004257019 0.0004257019 FALSE FALSE
MSTRG.14457.3 ENSG00000073670 HEK293_OSMI2_6hA HEK293_TMG_6hB ADAM11 protein_coding   9.67068 13.37464 7.178537 1.264564 0.6102902 -0.8968085 2.6923638 3.8570753 1.9246602 0.48889434 0.09645201 -0.9991626 0.2848792 0.28713333 0.2718667 -0.01526667 0.9511721549 0.0004257019 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000073670 E001 3.5826938 0.0068367151 7.257114e-01 8.515809e-01 17 44758988 44759178 191 + 0.543 0.658 0.511
ENSG00000073670 E002 4.3264643 0.0058740609 6.756707e-01 8.199728e-01 17 44759179 44759190 12 + 0.698 0.696 -0.008
ENSG00000073670 E003 10.7763891 0.0034269058 5.760030e-01 7.544178e-01 17 44759191 44759260 70 + 1.040 1.050 0.035
ENSG00000073670 E004 0.5227326 0.3648257163 7.463101e-01   17 44759325 44759487 163 + 0.177 0.154 -0.249
ENSG00000073670 E005 31.2371222 0.0254180564 8.776646e-02 2.595607e-01 17 44759722 44759897 176 + 1.535 1.447 -0.304
ENSG00000073670 E006 29.0099808 0.0042063068 4.133660e-02 1.581997e-01 17 44769718 44769794 77 + 1.496 1.419 -0.267
ENSG00000073670 E007 17.9796596 0.0130624996 2.216940e-01 4.555366e-01 17 44769982 44769985 4 + 1.277 1.227 -0.177
ENSG00000073670 E008 27.6533104 0.0016188412 6.491798e-02 2.137124e-01 17 44769986 44770048 63 + 1.461 1.402 -0.203
ENSG00000073670 E009 37.7906374 0.0015006539 3.974030e-01 6.262552e-01 17 44771584 44771669 86 + 1.536 1.555 0.064
ENSG00000073670 E010 34.9064722 0.0011371965 1.662725e-01 3.855973e-01 17 44771756 44771831 76 + 1.530 1.515 -0.052
ENSG00000073670 E011 33.9411323 0.0363017624 4.431492e-01 6.608382e-01 17 44772267 44772333 67 + 1.513 1.499 -0.049
ENSG00000073670 E012 37.7723797 0.0149899742 4.751872e-01 6.836745e-01 17 44772399 44772462 64 + 1.538 1.555 0.060
ENSG00000073670 E013 22.9019938 0.0108768747 1.872681e-01 4.134321e-01 17 44772463 44772466 4 + 1.378 1.333 -0.157
ENSG00000073670 E014 48.0328813 0.0047328348 1.655425e-01 3.846214e-01 17 44772857 44772931 75 + 1.661 1.651 -0.034
ENSG00000073670 E015 45.4159933 0.0008385858 9.566006e-01 9.801752e-01 17 44773014 44773085 72 + 1.572 1.650 0.263
ENSG00000073670 E016 77.9809685 0.0059546374 7.531257e-01 8.686218e-01 17 44773261 44773427 167 + 1.815 1.874 0.197
ENSG00000073670 E017 58.9979004 0.0393664867 3.454705e-01 5.830675e-01 17 44774295 44774379 85 + 1.757 1.727 -0.102
ENSG00000073670 E018 54.2188250 0.0226801839 1.546572e-01 3.689253e-01 17 44774492 44774582 91 + 1.734 1.686 -0.163
ENSG00000073670 E019 40.6482237 0.0392940496 2.195323e-01 4.528561e-01 17 44774698 44774749 52 + 1.622 1.559 -0.217
ENSG00000073670 E020 57.7887923 0.0364222861 6.341081e-01 7.930297e-01 17 44775212 44775311 100 + 1.712 1.734 0.074
ENSG00000073670 E021 43.8475575 0.0330737755 9.854051e-01 9.944919e-01 17 44775394 44775465 72 + 1.559 1.630 0.240
ENSG00000073670 E022 4.1759576 0.0093288030 3.583345e-01 5.944922e-01 17 44775558 44775583 26 + 0.739 0.658 -0.333
ENSG00000073670 E023 36.9378561 0.0461567913 7.152192e-01 8.450895e-01 17 44775584 44775676 93 + 1.533 1.544 0.038
ENSG00000073670 E024 42.5178115 0.0131059206 6.044290e-01 7.731799e-01 17 44776127 44776207 81 + 1.573 1.605 0.109
ENSG00000073670 E025 44.4446507 0.0027562403 1.512335e-01 3.641199e-01 17 44776745 44776795 51 + 1.627 1.612 -0.051
ENSG00000073670 E026 45.9640174 0.0008231256 2.647880e-01 5.040930e-01 17 44776899 44776962 64 + 1.627 1.637 0.036
ENSG00000073670 E027 56.3448715 0.0006496258 1.570840e-02 8.076441e-02 17 44777166 44777265 100 + 1.754 1.707 -0.161
ENSG00000073670 E028 0.6376527 0.0193874923 3.131884e-01   17 44777472 44777481 10 + 0.300 0.152 -1.253
ENSG00000073670 E029 71.5796289 0.0007659832 2.535624e-06 6.421224e-05 17 44777482 44777601 120 + 1.915 1.783 -0.445
ENSG00000073670 E030 78.5045767 0.0123168243 1.692944e-02 8.519113e-02 17 44777695 44777863 169 + 1.916 1.838 -0.260
ENSG00000073670 E031 56.4152870 0.0023281646 1.507780e-01 3.634058e-01 17 44777952 44778066 115 + 1.611 1.769 0.536
ENSG00000073670 E032 51.0639665 0.0018997205 8.608214e-02 2.565769e-01 17 44778152 44778242 91 + 1.554 1.730 0.596
ENSG00000073670 E033 30.8911179 0.2479217367 3.329692e-01 5.715942e-01 17 44779222 44779239 18 + 1.312 1.515 0.701
ENSG00000073670 E034 107.1789477 0.6529702021 3.186677e-01 5.584679e-01 17 44779240 44779669 430 + 1.790 2.054 0.888
ENSG00000073670 E035 439.2701577 1.4558376856 4.270967e-01 6.487870e-01 17 44779739 44781846 2108 + 2.381 2.668 0.956