ENSG00000072071

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340736 ENSG00000072071 HEK293_OSMI2_6hA HEK293_TMG_6hB ADGRL1 protein_coding protein_coding 18.56029 28.67454 11.00327 1.076523 0.204336 -1.38103 1.7532931 3.105890 0.6389868 0.5306358 0.2363159 -2.263383 0.09858750 0.1073667 0.0578000 -0.04956667 4.922788e-01 2.1046e-09 FALSE  
ENST00000361434 ENSG00000072071 HEK293_OSMI2_6hA HEK293_TMG_6hB ADGRL1 protein_coding protein_coding 18.56029 28.67454 11.00327 1.076523 0.204336 -1.38103 10.8572616 16.719903 4.4285224 0.8535979 0.8552983 -1.914278 0.55922917 0.5828333 0.4054000 -0.17743333 4.483188e-01 2.1046e-09 FALSE  
ENST00000592164 ENSG00000072071 HEK293_OSMI2_6hA HEK293_TMG_6hB ADGRL1 protein_coding protein_coding 18.56029 28.67454 11.00327 1.076523 0.204336 -1.38103 1.8251504 3.256261 0.5468121 0.3260249 0.3176615 -2.552378 0.08574167 0.1146667 0.0488000 -0.06586667 6.429143e-01 2.1046e-09 FALSE  
MSTRG.16588.1 ENSG00000072071 HEK293_OSMI2_6hA HEK293_TMG_6hB ADGRL1 protein_coding   18.56029 28.67454 11.00327 1.076523 0.204336 -1.38103 0.3765337 0.000000 1.4093719 0.0000000 0.7495734 7.149109 0.02758333 0.0000000 0.1257333 0.12573333 1.947021e-01 2.1046e-09 FALSE  
MSTRG.16588.15 ENSG00000072071 HEK293_OSMI2_6hA HEK293_TMG_6hB ADGRL1 protein_coding   18.56029 28.67454 11.00327 1.076523 0.204336 -1.38103 0.4680430 0.000000 0.8900002 0.0000000 0.2976895 6.491853 0.03807083 0.0000000 0.0806000 0.08060000 2.104600e-09 2.1046e-09 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_OSMI2_6hA log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
ENSG00000072071 E001 1408.077540 0.0027120693 0.0023650113 0.019473130 19 14147743 14151157 3415 - 3.005 3.093 0.292
ENSG00000072071 E002 36.528700 0.0036242536 0.1259454738 0.325418224 19 14151158 14151168 11 - 1.387 1.525 0.477
ENSG00000072071 E003 47.171834 0.0081860254 0.2649907637 0.504303541 19 14151169 14151207 39 - 1.521 1.627 0.363
ENSG00000072071 E004 76.372343 0.0023502978 0.0105300172 0.060375126 19 14151208 14151330 123 - 1.684 1.848 0.555
ENSG00000072071 E005 56.546669 0.0006550538 0.0812272916 0.247311819 19 14151331 14151392 62 - 1.590 1.714 0.420
ENSG00000072071 E006 49.548854 0.0007253378 0.0753509541 0.235551313 19 14151393 14151399 7 - 1.527 1.660 0.452
ENSG00000072071 E007 168.326449 0.0003323791 0.0004624221 0.005331865 19 14151400 14151615 216 - 2.040 2.183 0.481
ENSG00000072071 E008 83.711244 0.0005084701 0.5426472580 0.730993663 19 14152133 14152150 18 - 1.814 1.865 0.172
ENSG00000072071 E009 26.081590 0.0014303952 0.4626301869 0.674921984 19 14152151 14152222 72 - 1.387 1.350 -0.126
ENSG00000072071 E010 155.787436 0.0003829312 0.2107848560 0.442733926 19 14152309 14152437 129 - 2.135 2.115 -0.066
ENSG00000072071 E011 150.622157 0.0011879500 0.0019872572 0.016981022 19 14152517 14152613 97 - 2.172 2.083 -0.300
ENSG00000072071 E012 147.652270 0.0071759166 0.3077518805 0.548397175 19 14152784 14152912 129 - 2.125 2.090 -0.118
ENSG00000072071 E013 151.806570 1.1072254111 0.5556999082 0.740290437 19 14155359 14155527 169 - 2.023 2.133 0.368
ENSG00000072071 E014 104.598762 0.0083638006 0.2887115174 0.529415041 19 14156110 14156201 92 - 1.886 1.967 0.272
ENSG00000072071 E015 84.651951 0.0062825551 0.6650877719 0.813119669 19 14156658 14156724 67 - 1.861 1.855 -0.021
ENSG00000072071 E016 155.889259 0.0005183611 0.9012518639 0.952491342 19 14156925 14157145 221 - 2.100 2.126 0.088
ENSG00000072071 E017 173.064114 0.0003991598 0.1410286521 0.349083325 19 14157251 14157460 210 - 2.186 2.161 -0.083
ENSG00000072071 E018 156.758236 0.0003086023 0.0006125747 0.006690416 19 14157882 14158052 171 - 2.191 2.103 -0.295
ENSG00000072071 E019 166.612535 0.0002873271 0.0003115870 0.003847073 19 14158338 14158552 215 - 2.218 2.127 -0.303
ENSG00000072071 E020 100.884087 0.0005098983 0.0315855032 0.132016069 19 14159090 14159174 85 - 1.983 1.917 -0.220
ENSG00000072071 E021 78.451933 0.0006533884 0.0673830035 0.219185809 19 14159175 14159215 41 - 1.872 1.810 -0.212
ENSG00000072071 E022 104.101997 0.0005318419 0.0452974696 0.168330865 19 14159401 14159488 88 - 1.991 1.932 -0.197
ENSG00000072071 E023 103.877789 0.0005079049 0.1121837910 0.302757562 19 14159489 14159584 96 - 1.980 1.939 -0.140
ENSG00000072071 E024 80.273196 0.0005986524 0.3187538183 0.558542389 19 14159735 14159773 39 - 1.859 1.836 -0.078
ENSG00000072071 E025 123.292348 0.0003172246 0.0571591503 0.196373498 19 14160112 14160297 186 - 2.058 2.010 -0.159
ENSG00000072071 E026 6.261729 0.1381708148 0.0691158118 0.223014089 19 14160298 14160580 283 - 1.049 0.667 -1.484
ENSG00000072071 E027 66.172073 0.0006445709 0.1013195258 0.284214704 19 14160593 14160696 104 - 1.802 1.743 -0.201
ENSG00000072071 E028 134.329273 0.0011180488 0.2415341861 0.478277793 19 14161312 14161626 315 - 2.077 2.056 -0.071
ENSG00000072071 E029 194.595671 0.0010490853 0.0007297298 0.007693376 19 14162606 14162947 342 - 2.283 2.199 -0.282
ENSG00000072071 E030 251.663466 0.0002592574 0.0006772949 0.007244047 19 14162948 14163406 459 - 2.381 2.316 -0.216
ENSG00000072071 E031 15.256859 0.0281107627 0.9362798718 0.970357787 19 14164621 14164705 85 - 1.121 1.163 0.149
ENSG00000072071 E032 10.855408 0.0031278655 0.0435422688 0.163964671 19 14167016 14167030 15 - 1.159 0.963 -0.713
ENSG00000072071 E033 6.990513 0.1897430642 0.2212969663 0.455056725 19 14170488 14170681 194 - 1.050 0.748 -1.154
ENSG00000072071 E034 66.964383 0.4868095642 0.3104995087 0.550986490 19 14170682 14170791 110 - 1.582 1.800 0.739
ENSG00000072071 E035 113.180705 0.0003980672 0.1037943748 0.288540852 19 14177531 14177744 214 - 1.918 2.006 0.298
ENSG00000072071 E036 90.786026 0.0025179329 0.6634641564 0.812066917 19 14183533 14183697 165 - 1.858 1.903 0.150
ENSG00000072071 E037 74.922510 0.0005650460 0.0014252259 0.013077379 19 14205985 14206137 153 - 1.657 1.846 0.640
ENSG00000072071 E038 39.385299 0.0090099658 0.0127876652 0.069574846 19 14206138 14206310 173 - 1.342 1.578 0.811
ENSG00000072071 E039 1.034866 0.3256675723 0.8272002898   19 14206843 14206944 102 - 0.198 0.285 0.681