ENSG00000070061

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-7 / 7
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000537196	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	protein_coding	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	12.3951540	10.2738716	13.8495885	1.9499186	0.5051469	0.4305009	0.39531250	0.51010000	0.31546667	-0.19463333	7.661874e-06	3.799136e-13	FALSE	TRUE
ENST00000674535	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	protein_coding	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	6.7644387	2.8447461	11.1835366	0.5158911	0.4653042	1.9712316	0.17750833	0.14246667	0.25483333	0.11236667	7.098471e-04	3.799136e-13	FALSE	TRUE
ENST00000675052	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	protein_coding	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	2.1791514	1.5211522	2.5740416	0.3994710	0.4042567	0.7550116	0.06365417	0.07336667	0.05866667	-0.01470000	8.205239e-01	3.799136e-13	FALSE	TRUE
ENST00000675321	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	nonsense_mediated_decay	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	2.2129243	0.0000000	2.5518406	0.0000000	0.2962656	8.0010369	0.04886250	0.00000000	0.05820000	0.05820000	3.799136e-13	3.799136e-13	TRUE	TRUE
ENST00000675335	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	nonsense_mediated_decay	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	2.0672441	0.4445291	4.2006686	0.4445291	0.5839767	3.2116048	0.04962083	0.03296667	0.09523333	0.06226667	2.893196e-01	3.799136e-13	FALSE	TRUE
ENST00000676162	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding	processed_transcript	34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	1.4044571	0.0000000	0.1468945	0.0000000	0.1468945	3.9717226	0.05659167	0.00000000	0.00320000	0.00320000	9.381889e-01	3.799136e-13	FALSE	TRUE
MSTRG.33210.3	ENSG00000070061	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ELP1	protein_coding		34.32196	19.91044	43.91596	3.21685	1.713174	1.140825	0.9366884	1.5315320	0.0000000	0.7759223	0.0000000	-7.2682210	0.03228333	0.06633333	0.00000000	-0.06633333	1.805770e-01	3.799136e-13	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 94
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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end
width
strand
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HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000070061	E001	0.5352391	0.2556594020	2.146460e-01		9	108866898	108867515	618	-	0.091	0.357	2.459
ENSG00000070061	E002	0.1308682	0.0326491905	2.664887e-01		9	108867516	108867516	1	-	0.000	0.159	12.701
ENSG00000070061	E003	0.1308682	0.0326491905	2.664887e-01		9	108867517	108867537	21	-	0.000	0.159	12.701
ENSG00000070061	E004	0.3336024	0.0244411696	8.080839e-02		9	108867538	108867539	2	-	0.000	0.276	13.705
ENSG00000070061	E005	14.7449848	0.0568132207	3.290497e-01	5.680614e-01	9	108867540	108868172	633	-	1.119	1.266	0.521
ENSG00000070061	E006	52.1017431	0.0007035001	3.724181e-02	1.475959e-01	9	108868173	108868445	273	-	1.663	1.779	0.393
ENSG00000070061	E007	53.8069638	0.0015450517	9.776514e-03	5.715607e-02	9	108868446	108868549	104	-	1.667	1.812	0.491
ENSG00000070061	E008	57.5289190	0.0067927243	1.967919e-03	1.685315e-02	9	108868550	108868640	91	-	1.666	1.870	0.690
ENSG00000070061	E009	39.4814630	0.0093673127	3.633156e-02	1.451442e-01	9	108868641	108868650	10	-	1.519	1.684	0.563
ENSG00000070061	E010	78.0359489	0.0024557275	8.757696e-03	5.274560e-02	9	108868651	108868670	20	-	1.823	1.957	0.450
ENSG00000070061	E011	95.3276676	0.0076074438	7.950317e-03	4.909446e-02	9	108868671	108868720	50	-	1.897	2.061	0.552
ENSG00000070061	E012	414.4724665	0.0070639987	6.612370e-05	1.057574e-03	9	108868721	108869030	310	-	2.519	2.714	0.648
ENSG00000070061	E013	260.4404884	0.0046309642	4.853610e-07	1.508243e-05	9	108869031	108869114	84	-	2.308	2.523	0.716
ENSG00000070061	E014	253.5547029	0.0065651981	5.108764e-04	5.776587e-03	9	108869115	108869182	68	-	2.315	2.491	0.588
ENSG00000070061	E015	6.8752358	0.0971236018	3.262141e-02	1.350331e-01	9	108870454	108870553	100	-	0.701	1.074	1.430
ENSG00000070061	E016	3.1596847	0.0078871060	8.410712e-03	5.120572e-02	9	108872661	108872801	141	-	0.421	0.830	1.815
ENSG00000070061	E017	232.2151238	0.0009488794	7.338793e-08	2.815215e-06	9	108874895	108874963	69	-	2.284	2.445	0.537
ENSG00000070061	E018	133.0392023	0.0003442587	2.899987e-05	5.239755e-04	9	108874964	108874970	7	-	2.050	2.194	0.485
ENSG00000070061	E019	0.7392585	0.0854015962	1.191893e-01		9	108874971	108875632	662	-	0.091	0.371	2.528
ENSG00000070061	E020	0.5067846	0.0206879980	1.000000e+00		9	108875633	108875735	103	-	0.167	0.160	-0.074
ENSG00000070061	E021	0.7860845	0.0170622932	7.723284e-02		9	108875736	108876701	966	-	0.337	0.000	-13.216
ENSG00000070061	E022	0.1779838	0.0359444683	9.086873e-01		9	108876898	108876986	89	-	0.092	0.000	-10.896
ENSG00000070061	E023	0.3447487	0.6521373335	1.927750e-01		9	108876987	108877612	626	-	0.000	0.281	13.731
ENSG00000070061	E024	0.5587019	0.3462794319	1.000000e+00		9	108877613	108877800	188	-	0.170	0.163	-0.073
ENSG00000070061	E025	1.3089191	0.4083671494	1.533459e-01		9	108877801	108877994	194	-	0.170	0.529	2.309
ENSG00000070061	E026	293.6675755	0.0002550197	1.282666e-08	5.869744e-07	9	108877995	108878149	155	-	2.397	2.533	0.455
ENSG00000070061	E027	267.7735317	0.0002265727	1.769555e-08	7.863664e-07	9	108878623	108878750	128	-	2.357	2.497	0.465
ENSG00000070061	E028	0.0000000				9	108878751	108878988	238	-
ENSG00000070061	E029	148.8498108	0.0011722461	7.458264e-03	4.682903e-02	9	108879446	108879460	15	-	2.121	2.223	0.341
ENSG00000070061	E030	235.5092925	0.0024341118	2.094884e-02	9.916933e-02	9	108879461	108879557	97	-	2.322	2.414	0.308
ENSG00000070061	E031	225.1997837	0.0002476137	5.860070e-04	6.456723e-03	9	108880052	108880165	114	-	2.299	2.397	0.325
ENSG00000070061	E032	3.6198617	0.4088933101	9.725758e-01	9.882499e-01	9	108880166	108880943	778	-	0.641	0.659	0.077
ENSG00000070061	E033	1.4209042	0.0132410403	9.136241e-01	9.589181e-01	9	108880944	108881662	719	-	0.381	0.368	-0.077
ENSG00000070061	E034	5.4474771	0.0055010828	3.670169e-01	6.015230e-01	9	108881663	108881704	42	-	0.755	0.884	0.506
ENSG00000070061	E035	151.7215874	0.0004290535	3.953325e-02	1.535497e-01	9	108881705	108881765	61	-	2.138	2.213	0.251
ENSG00000070061	E036	150.0000079	0.0011099285	8.595988e-02	2.563520e-01	9	108882125	108882187	63	-	2.135	2.204	0.230
ENSG00000070061	E037	2.4651229	0.1421704642	3.846652e-01	6.162231e-01	9	108882188	108882562	375	-	0.421	0.629	0.994
ENSG00000070061	E038	0.8030126	0.3015590261	7.144467e-01		9	108884796	108884912	117	-	0.227	0.282	0.412
ENSG00000070061	E039	0.2922838	0.0264064403	6.559737e-01		9	108885768	108885872	105	-	0.091	0.159	0.920
ENSG00000070061	E040	157.7155111	0.0003146636	4.740485e-02	1.735269e-01	9	108889332	108889393	62	-	2.156	2.226	0.236
ENSG00000070061	E041	0.0000000				9	108889645	108889684	40	-
ENSG00000070061	E042	299.8275202	0.0001607148	2.512940e-04	3.234218e-03	9	108891203	108891404	202	-	2.425	2.515	0.300
ENSG00000070061	E043	227.7699905	0.0001998134	1.698488e-02	8.541378e-02	9	108892986	108893083	98	-	2.314	2.385	0.235
ENSG00000070061	E044	1.0843377	0.0180211479	7.175338e-01		9	108893084	108893942	859	-	0.336	0.276	-0.397
ENSG00000070061	E045	225.6318390	0.0019768119	9.923088e-02	2.804314e-01	9	108893943	108894066	124	-	2.311	2.375	0.215
ENSG00000070061	E046	0.3641499	0.0308295091	6.524851e-01		9	108894067	108894088	22	-	0.091	0.160	0.926
ENSG00000070061	E047	240.3069941	0.0002098283	2.472729e-02	1.113745e-01	9	108896496	108896644	149	-	2.338	2.404	0.220
ENSG00000070061	E048	2.3599643	0.0977325846	3.667859e-01	6.013272e-01	9	108896645	108896890	246	-	0.558	0.369	-0.969
ENSG00000070061	E049	4.4074221	0.0089014948	2.420831e-01	4.789068e-01	9	108896891	108896952	62	-	0.655	0.830	0.712
ENSG00000070061	E050	181.2481052	0.0003206307	2.911024e-01	5.316773e-01	9	108896953	108897038	86	-	2.228	2.270	0.138
ENSG00000070061	E051	206.9459336	0.0003703009	7.362440e-01	8.581176e-01	9	108897148	108897283	136	-	2.299	2.302	0.009
ENSG00000070061	E052	83.3189607	0.0004770631	9.074380e-02	2.651295e-01	9	108897284	108897285	2	-	1.924	1.866	-0.196
ENSG00000070061	E053	1.6202418	0.0849340732	3.656863e-01	6.004984e-01	9	108897286	108898135	850	-	0.336	0.510	0.938
ENSG00000070061	E054	0.0000000				9	108898136	108898234	99	-
ENSG00000070061	E055	0.4536995	0.2030283929	1.000000e+00		9	108898235	108898501	267	-	0.167	0.158	-0.100
ENSG00000070061	E056	130.9757645	0.0006278495	1.295187e-01	3.310659e-01	9	108898502	108898581	80	-	2.113	2.073	-0.136
ENSG00000070061	E057	162.1291578	0.0004961276	1.014551e-01	2.844327e-01	9	108898671	108898749	79	-	2.205	2.167	-0.130
ENSG00000070061	E058	169.3668309	0.0010459525	4.515714e-01	6.667815e-01	9	108899822	108899895	74	-	2.216	2.202	-0.046
ENSG00000070061	E059	210.2090883	0.0003202238	5.278632e-01	7.205185e-01	9	108900260	108900375	116	-	2.306	2.301	-0.017
ENSG00000070061	E060	186.0115226	0.0002425815	7.199825e-02	2.288022e-01	9	108901425	108901530	106	-	2.264	2.226	-0.126
ENSG00000070061	E061	135.9559525	0.0003446310	5.722506e-04	6.328556e-03	9	108901628	108901681	54	-	2.148	2.046	-0.342
ENSG00000070061	E062	181.9603032	0.0003222274	1.245474e-04	1.793827e-03	9	108902839	108902942	104	-	2.277	2.179	-0.328
ENSG00000070061	E063	188.0918217	0.0002445813	1.594895e-02	8.161571e-02	9	108903563	108903658	96	-	2.276	2.222	-0.182
ENSG00000070061	E064	98.3074718	0.0007574568	7.322926e-02	2.312902e-01	9	108903659	108903669	11	-	1.997	1.938	-0.197
ENSG00000070061	E065	229.9943007	0.0019547522	1.072833e-01	2.944916e-01	9	108906303	108906485	183	-	2.359	2.316	-0.142
ENSG00000070061	E066	10.8726809	0.2682579643	3.547199e-01	5.914714e-01	9	108906486	108908304	1819	-	1.100	0.951	-0.547
ENSG00000070061	E067	170.5868553	0.0004261594	9.908014e-04	9.841543e-03	9	108908305	108908404	100	-	2.244	2.157	-0.291
ENSG00000070061	E068	236.0381584	0.0005339499	2.012501e-06	5.251521e-05	9	108911010	108911180	171	-	2.394	2.279	-0.385
ENSG00000070061	E069	0.1614157	0.0338335063	9.087376e-01		9	108911181	108911211	31	-	0.091	0.000	-10.895
ENSG00000070061	E070	256.9566523	0.0057072787	4.742885e-03	3.323777e-02	9	108912264	108912494	231	-	2.430	2.315	-0.383
ENSG00000070061	E071	142.5417028	0.0003383924	1.518080e-03	1.373934e-02	9	108916204	108916297	94	-	2.168	2.078	-0.302
ENSG00000070061	E072	0.8040577	0.0210759196	8.268959e-01		9	108916298	108917546	1249	-	0.231	0.276	0.335
ENSG00000070061	E073	168.1635912	0.0004933624	1.151146e-06	3.209507e-05	9	108917547	108917662	116	-	2.255	2.116	-0.463
ENSG00000070061	E074	104.7134659	0.0035429382	1.217173e-03	1.156063e-02	9	108917663	108917670	8	-	2.050	1.906	-0.484
ENSG00000070061	E075	73.5809192	0.1645315419	5.002564e-01	7.009365e-01	9	108917671	108918810	1140	-	1.870	1.818	-0.176
ENSG00000070061	E076	156.5127128	0.0002953011	2.407367e-06	6.136689e-05	9	108918811	108918901	91	-	2.221	2.087	-0.449
ENSG00000070061	E077	20.3947700	0.1621048883	2.173836e-01	4.502772e-01	9	108918902	108919252	351	-	1.370	1.169	-0.709
ENSG00000070061	E078	157.9020459	0.0002616613	9.432124e-06	1.993766e-04	9	108919253	108919349	97	-	2.221	2.097	-0.415
ENSG00000070061	E079	0.5767453	0.0199518516	1.097831e-01		9	108920316	108920690	375	-	0.091	0.367	2.506
ENSG00000070061	E080	0.5963342	0.0226449284	6.737173e-01		9	108920691	108920783	93	-	0.231	0.159	-0.664
ENSG00000070061	E081	2.0974743	0.3577415672	9.337416e-01	9.689631e-01	9	108920784	108922841	2058	-	0.487	0.454	-0.164
ENSG00000070061	E082	163.4851472	0.0002595634	1.505479e-04	2.104932e-03	9	108922842	108922927	86	-	2.228	2.127	-0.341
ENSG00000070061	E083	178.4500546	0.0003465718	1.723536e-08	7.670234e-07	9	108926523	108926595	73	-	2.282	2.126	-0.519
ENSG00000070061	E084	116.2670443	0.0025764844	2.366034e-05	4.408680e-04	9	108926596	108926603	8	-	2.103	1.932	-0.573
ENSG00000070061	E085	185.6286024	0.0014401496	1.034315e-05	2.159460e-04	9	108927372	108927453	82	-	2.295	2.160	-0.450
ENSG00000070061	E086	211.1561969	0.0005342539	3.320108e-10	2.109355e-08	9	108929769	108929921	153	-	2.360	2.194	-0.554
ENSG00000070061	E087	131.2965103	0.0003303214	1.780229e-13	2.109165e-11	9	108930997	108931056	60	-	2.175	1.929	-0.824
ENSG00000070061	E088	76.9840138	0.0005316083	3.646828e-07	1.171171e-05	9	108931057	108931080	24	-	1.938	1.720	-0.735
ENSG00000070061	E089	117.2644121	0.0005511391	6.656236e-07	1.995026e-05	9	108931081	108931199	119	-	2.106	1.936	-0.573
ENSG00000070061	E090	47.3233406	0.0009100959	4.844180e-04	5.533790e-03	9	108931200	108931201	2	-	1.721	1.535	-0.631
ENSG00000070061	E091	37.3160768	0.1916121511	2.784800e-01	5.185727e-01	9	108931202	108933863	2662	-	1.611	1.461	-0.513
ENSG00000070061	E092	146.4479284	0.0002873082	1.690430e-06	4.505947e-05	9	108933864	108934063	200	-	2.194	2.053	-0.473
ENSG00000070061	E093	46.1005724	0.0009028090	3.333896e-02	1.369948e-01	9	108934064	108934328	265	-	1.686	1.578	-0.368
ENSG00000070061	E094	0.1614157	0.0338335063	9.087376e-01		9	108934367	108934449	83	-	0.091	0.000	-10.895

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000070061

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3