• ENSG00000067992
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000067992

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000379162 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding protein_coding 6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 0.6697375 0.00000000 1.02904068 0.00000000 0.13757374 6.699108 0.08848333 0.0000000 0.161066667 0.16106667 3.402281e-10 3.402281e-10 FALSE TRUE
ENST00000568479 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding protein_coding 6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 2.3555497 1.86250097 3.02155597 0.31084958 0.39333638 0.695092 0.35875417 0.3806333 0.471466667 0.09083333 7.835464e-01 3.402281e-10 FALSE TRUE
MSTRG.34034.1 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding   6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 1.0192171 2.04098749 0.32710383 0.87170883 0.32710383 -2.605054 0.15600833 0.3684000 0.054266667 -0.31413333 1.465422e-01 3.402281e-10 TRUE TRUE
MSTRG.34034.2 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding   6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 0.4995805 0.08484434 0.28318406 0.08484434 0.28318406 1.628173 0.06153750 0.0241000 0.046966667 0.02286667 1.000000e+00 3.402281e-10 FALSE TRUE
MSTRG.34034.3 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding   6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 1.5706400 0.44779410 1.53002573 0.22707005 0.50963694 1.750184 0.20941250 0.0778000 0.236400000 0.15860000 6.033172e-01 3.402281e-10 FALSE TRUE
MSTRG.34034.4 ENSG00000067992 HEK293_OSMI2_6hA HEK293_TMG_6hB PDK3 protein_coding   6.994223 5.087779 6.376773 1.027164 0.2932718 0.3252184 0.7360823 0.46558588 0.03968273 0.23285807 0.03968273 -3.258890 0.10253750 0.1150667 0.006566667 -0.10850000 2.099893e-01 3.402281e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000067992 E001 0.2735028 0.0264598863 9.115683e-01   X 24382620 24382623 4 + 0.120 0.123 0.034
ENSG00000067992 E002 3.7540255 0.0853329201 1.429606e-01 3.519183e-01 X 24382624 24382662 39 + 0.467 0.798 1.451
ENSG00000067992 E003 0.1308682 0.0314494867 5.530030e-01   X 24465244 24465269 26 + 0.000 0.122 10.144
ENSG00000067992 E004 1.7014509 0.2091626073 5.874147e-03 3.911867e-02 X 24465270 24465285 16 + 0.000 0.637 12.680
ENSG00000067992 E005 22.6020333 0.0078010666 3.342138e-01 5.727900e-01 X 24465286 24465561 276 + 1.379 1.371 -0.028
ENSG00000067992 E006 38.1827084 0.0009050703 5.464092e-04 6.096771e-03 X 24494742 24494883 142 + 1.644 1.523 -0.411
ENSG00000067992 E007 37.3471918 0.0104948107 1.092837e-03 1.062147e-02 X 24498829 24498900 72 + 1.647 1.485 -0.553
ENSG00000067992 E008 0.9512567 0.2373027878 1.434371e-01   X 24498901 24500155 1255 + 0.409 0.125 -2.237
ENSG00000067992 E009 59.1796838 0.0009251142 6.680943e-06 1.480013e-04 X 24503327 24503511 185 + 1.836 1.702 -0.452
ENSG00000067992 E010 33.9053956 0.0062765897 9.321779e-02 2.697358e-01 X 24505209 24505256 48 + 1.561 1.516 -0.155
ENSG00000067992 E011 34.5564851 0.0011549471 3.718147e-02 1.473919e-01 X 24505257 24505298 42 + 1.572 1.523 -0.168
ENSG00000067992 E012 40.9637089 0.0010316870 2.612413e-03 2.104292e-02 X 24518933 24519010 78 + 1.662 1.571 -0.309
ENSG00000067992 E013 1.9626780 0.0121381584 9.068293e-03 5.413022e-02 X 24524183 24525396 1214 + 0.622 0.218 -2.290
ENSG00000067992 E014 0.7569420 0.1427655067 7.859159e-01   X 24525397 24526197 801 + 0.214 0.294 0.597
ENSG00000067992 E015 41.0836482 0.0011669567 2.004753e-01 4.302799e-01 X 24526198 24526274 77 + 1.614 1.619 0.015
ENSG00000067992 E016 42.2584971 0.0008114445 2.111885e-02 9.972657e-02 X 24527574 24527675 102 + 1.653 1.604 -0.166
ENSG00000067992 E017 46.0229623 0.0033009709 5.114916e-03 3.521998e-02 X 24528076 24528186 111 + 1.703 1.617 -0.291
ENSG00000067992 E018 48.3596044 0.0008595576 1.818529e-02 8.963488e-02 X 24531657 24531770 114 + 1.705 1.661 -0.151
ENSG00000067992 E019 50.6643408 0.0022390072 5.801594e-01 7.572742e-01 X 24533929 24534068 140 + 1.680 1.728 0.160
ENSG00000067992 E020 6.3288905 0.0042469280 1.198346e-02 6.636666e-02 X 24534069 24534656 588 + 0.968 0.720 -0.964
ENSG00000067992 E021 1.7375785 0.0114707741 8.005681e-02 2.449545e-01 X 24534657 24535492 836 + 0.550 0.296 -1.383
ENSG00000067992 E022 89.9536957 0.0011147328 5.031227e-01 7.029181e-01 X 24539134 24539726 593 + 1.930 1.980 0.167
ENSG00000067992 E023 33.6226327 0.0163999066 4.185327e-02 1.595756e-01 X 24539727 24540245 519 + 1.588 1.483 -0.360
ENSG00000067992 E024 960.9186497 0.0049653947 2.618652e-07 8.747193e-06 X 24540246 24550466 10221 + 2.887 3.060 0.575