ENSG00000067900

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-3 / 3
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000635540	ENSG00000067900	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ROCK1	protein_coding	nonsense_mediated_decay	14.90725	8.741415	26.51521	1.85857	0.5407197	1.599776	8.2415681	6.1082636	14.1321715	1.4056872	0.19891007	1.20880950	0.61300833	0.6910667	0.53316667	-0.15790000	0.012187475	0.001513802	TRUE	TRUE
MSTRG.15545.2	ENSG00000067900	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ROCK1	protein_coding		14.90725	8.741415	26.51521	1.85857	0.5407197	1.599776	0.4827848	0.5495243	0.5611882	0.2154062	0.08629171	0.02976545	0.05441667	0.0574000	0.02106667	-0.03633333	0.214115413	0.001513802	FALSE	TRUE
MSTRG.15545.5	ENSG00000067900	HEK293_OSMI2_6hA	HEK293_TMG_6hB	ROCK1	protein_coding		14.90725	8.741415	26.51521	1.85857	0.5407197	1.599776	4.1664286	1.2270261	8.0924187	0.2751895	0.12154774	2.71147668	0.19676667	0.1438333	0.30526667	0.16143333	0.001513802	0.001513802	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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width
strand
HEK293_TMG_6hB
HEK293_OSMI2_6hA
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_6hB	HEK293_OSMI2_6hA	log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hB

ENSG00000067900	E001	7.4688840	0.0043551046	7.061022e-03	4.490597e-02	18	20946906	20948492	1587	-	0.776	1.099	1.217
ENSG00000067900	E002	15.8554603	0.0025565720	3.464537e-02	1.406479e-01	18	20948493	20949951	1459	-	1.121	1.314	0.685
ENSG00000067900	E003	315.2492416	0.0052897038	2.335788e-08	1.008826e-06	18	20949952	20950948	997	-	2.380	2.610	0.766
ENSG00000067900	E004	40.9352495	0.0011131517	6.931720e-04	7.385442e-03	18	20950949	20950967	19	-	1.514	1.714	0.682
ENSG00000067900	E005	106.8039158	0.0003863236	2.695289e-07	8.978464e-06	18	20950968	20951083	116	-	1.930	2.120	0.634
ENSG00000067900	E006	215.0634797	0.0002492354	2.018505e-08	8.841593e-07	18	20951084	20951387	304	-	2.249	2.397	0.494
ENSG00000067900	E007	1.0835299	0.0148963668	1.337705e-01		18	20953290	20953577	288	-	0.210	0.479	1.697
ENSG00000067900	E008	139.0798678	0.0004502018	5.744237e-04	6.349695e-03	18	20953578	20953785	208	-	2.073	2.190	0.391
ENSG00000067900	E009	99.2926770	0.0011109137	5.802328e-01	7.573293e-01	18	20954783	20954853	71	-	1.959	1.986	0.093
ENSG00000067900	E010	152.1414479	0.0019203182	2.640456e-01	5.033226e-01	18	20954854	20955044	191	-	2.136	2.181	0.151
ENSG00000067900	E011	106.5381481	0.0005429858	1.946338e-02	9.405370e-02	18	20955167	20955245	79	-	1.967	2.059	0.309
ENSG00000067900	E012	1.2375010	0.2496319103	4.821915e-01		18	20955246	20955467	222	-	0.357	0.180	-1.317
ENSG00000067900	E013	114.7787520	0.0004455631	3.641871e-03	2.715700e-02	18	20959840	20959928	89	-	1.992	2.101	0.364
ENSG00000067900	E014	122.5458686	0.0003771316	5.552379e-03	3.748297e-02	18	20960136	20960206	71	-	2.022	2.123	0.336
ENSG00000067900	E015	0.1614157	0.0342227478	1.000000e+00		18	20960663	20960711	49	-	0.082	0.000	-7.813
ENSG00000067900	E016	162.8518450	0.0017586395	2.645719e-01	5.038169e-01	18	20966917	20967076	160	-	2.161	2.206	0.150
ENSG00000067900	E017	158.2908945	0.0006014090	7.940110e-01	8.927319e-01	18	20967752	20967940	189	-	2.159	2.172	0.046
ENSG00000067900	E018	0.4950181	0.0217681645	1.870207e-01		18	20968485	20968771	287	-	0.082	0.302	2.282
ENSG00000067900	E019	106.4047058	0.0062473953	6.427198e-01	7.986688e-01	18	20968772	20968860	89	-	2.000	1.986	-0.045
ENSG00000067900	E020	101.1331451	0.0007429920	4.609230e-01	6.738057e-01	18	20969115	20969208	94	-	1.962	1.997	0.118
ENSG00000067900	E021	5.4860010	0.0048512075	3.907786e-01	6.209940e-01	18	20969209	20969354	146	-	0.819	0.701	-0.474
ENSG00000067900	E022	7.4516997	0.0038733256	5.373265e-02	1.884366e-01	18	20969958	20970347	390	-	0.958	0.701	-1.005
ENSG00000067900	E023	105.3451349	0.0032779585	7.511552e-02	2.350706e-01	18	20970348	20970513	166	-	1.962	2.049	0.289
ENSG00000067900	E024	84.1932488	0.0057787369	6.976260e-01	8.339911e-01	18	20979910	20980004	95	-	1.886	1.910	0.081
ENSG00000067900	E025	85.3064978	0.0013745291	5.115550e-01	7.091681e-01	18	20982763	20982832	70	-	1.889	1.926	0.124
ENSG00000067900	E026	138.4810977	0.0036642811	8.674630e-01	9.345435e-01	18	20984351	20984535	185	-	2.104	2.120	0.053
ENSG00000067900	E027	166.2037441	0.0002803782	5.264358e-01	7.194884e-01	18	20986950	20987110	161	-	2.190	2.177	-0.044
ENSG00000067900	E028	152.3165184	0.0038938546	8.562231e-02	2.557135e-01	18	20991176	20991326	151	-	2.169	2.090	-0.266
ENSG00000067900	E029	118.5845180	0.0004272161	1.979312e-01	4.270847e-01	18	20992831	20992937	107	-	2.053	2.011	-0.140
ENSG00000067900	E030	198.8953094	0.0013524880	1.068423e-02	6.104254e-02	18	21006351	21006593	243	-	2.286	2.207	-0.266
ENSG00000067900	E031	72.3834924	0.0018977199	2.611077e-02	1.156742e-01	18	21006594	21006597	4	-	1.859	1.754	-0.357
ENSG00000067900	E032	112.2208147	0.0006501404	1.789069e-02	8.867440e-02	18	21006699	21006790	92	-	2.039	1.954	-0.286
ENSG00000067900	E033	134.3281276	0.0003483548	4.182903e-01	6.423491e-01	18	21008059	21008194	136	-	2.101	2.080	-0.071
ENSG00000067900	E034	89.8970008	0.0005337583	2.387347e-01	4.751611e-01	18	21015431	21015479	49	-	1.935	1.892	-0.144
ENSG00000067900	E035	1.7271674	0.0231437089	8.931629e-01	9.482576e-01	18	21017021	21017098	78	-	0.424	0.399	-0.132
ENSG00000067900	E036	81.8586623	0.0005069423	7.029807e-01	8.374825e-01	18	21020151	21020236	86	-	1.883	1.872	-0.037
ENSG00000067900	E037	42.4535882	0.0009389833	2.522035e-02	1.128791e-01	18	21020237	21020239	3	-	1.634	1.501	-0.453
ENSG00000067900	E038	77.1511596	0.0012942503	2.768250e-03	2.198225e-02	18	21023620	21023680	61	-	1.889	1.747	-0.478
ENSG00000067900	E039	121.2273160	0.0003416670	8.583124e-05	1.315772e-03	18	21028776	21028935	160	-	2.088	1.949	-0.465
ENSG00000067900	E040	101.0362662	0.0004783254	2.227667e-05	4.189933e-04	18	21039472	21039563	92	-	2.016	1.847	-0.567
ENSG00000067900	E041	103.3694826	0.0007836662	2.606697e-05	4.779320e-04	18	21042097	21042235	139	-	2.028	1.859	-0.567
ENSG00000067900	E042	102.9858297	0.0007093121	6.379644e-04	6.904220e-03	18	21042565	21042709	145	-	2.017	1.883	-0.451
ENSG00000067900	E043	83.7501685	0.0168888386	1.850273e-01	4.105505e-01	18	21044102	21044186	85	-	1.921	1.805	-0.390
ENSG00000067900	E044	1.1608332	0.0164118011	5.754481e-02		18	21045045	21045291	247	-	0.389	0.000	-10.622
ENSG00000067900	E045	106.4909620	0.0097254856	1.275696e-01	3.279977e-01	18	21045292	21045467	176	-	2.021	1.918	-0.347
ENSG00000067900	E046	97.4185242	0.0004571381	6.496796e-05	1.042134e-03	18	21049092	21049229	138	-	1.999	1.838	-0.540
ENSG00000067900	E047	87.8973757	0.0004636008	8.828557e-06	1.884243e-04	18	21049780	21049880	101	-	1.960	1.770	-0.641
ENSG00000067900	E048	67.9114472	0.0005974060	1.472886e-03	1.342403e-02	18	21070532	21070613	82	-	1.843	1.692	-0.510
ENSG00000067900	E049	172.3529939	0.0130686960	1.814626e-02	8.951785e-02	18	21110818	21111813	996	-	2.242	2.082	-0.537

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000067900

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3