• ENSG00000005812
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000005812

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000355619 ENSG00000005812 HEK293_OSMI2_6hA HEK293_TMG_6hB FBXL3 protein_coding protein_coding 32.74339 9.981388 54.54896 0.9207718 3.330671 2.449059 19.685862 4.692342 34.850495 0.5423246 0.6729000 2.8901418 0.55527500 0.4683333 0.64253333 0.17420000 4.470057e-02 1.528688e-12 FALSE TRUE
ENST00000477982 ENSG00000005812 HEK293_OSMI2_6hA HEK293_TMG_6hB FBXL3 protein_coding processed_transcript 32.74339 9.981388 54.54896 0.9207718 3.330671 2.449059 2.549662 1.154852 4.543704 0.5829920 0.4464367 1.9668934 0.08824583 0.1059667 0.08290000 -0.02306667 9.800349e-01 1.528688e-12 FALSE FALSE
ENST00000485797 ENSG00000005812 HEK293_OSMI2_6hA HEK293_TMG_6hB FBXL3 protein_coding processed_transcript 32.74339 9.981388 54.54896 0.9207718 3.330671 2.449059 1.807200 1.634001 2.856895 0.3786143 0.4095259 0.8022783 0.10966667 0.1698333 0.05183333 -0.11800000 9.039537e-02 1.528688e-12   FALSE
MSTRG.8917.2 ENSG00000005812 HEK293_OSMI2_6hA HEK293_TMG_6hB FBXL3 protein_coding   32.74339 9.981388 54.54896 0.9207718 3.330671 2.449059 1.124433 2.022854 1.809494 0.5096084 0.4337932 -0.1599692 0.07265000 0.2026333 0.03316667 -0.16946667 4.473304e-04 1.528688e-12   FALSE
MSTRG.8917.9 ENSG00000005812 HEK293_OSMI2_6hA HEK293_TMG_6hB FBXL3 protein_coding   32.74339 9.981388 54.54896 0.9207718 3.330671 2.449059 4.615225 0.000000 7.273411 0.0000000 1.3994550 9.5084704 0.08271250 0.0000000 0.13136667 0.13136667 1.528688e-12 1.528688e-12   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_6hBColumn filter
HEK293_OSMI2_6hAColumn filter
log2fold_HEK293_OSMI2_6hA_HEK293_TMG_6hBColumn filter
ENSG00000005812 E001 10.6537376 0.273774613 1.723057e-02 8.629505e-02 13 76992348 76992520 173 - 0.728 1.433 2.585
ENSG00000005812 E002 10.9579662 0.067057232 6.717296e-06 1.486127e-04 13 76992598 76992720 123 - 0.712 1.480 2.815
ENSG00000005812 E003 32.3306645 0.400633706 4.379787e-03 3.126213e-02 13 76992721 76992951 231 - 1.093 1.958 2.978
ENSG00000005812 E004 176.7341584 1.405673059 2.831450e-01 5.235914e-01 13 76999137 77002049 2913 - 1.982 2.481 1.668
ENSG00000005812 E005 1096.6601491 0.187399338 1.475705e-01 3.588276e-01 13 77005260 77007564 2305 - 2.892 2.889 -0.010
ENSG00000005812 E006 231.6849855 0.001581073 2.811619e-11 2.236429e-09 13 77007565 77007788 224 - 2.239 2.130 -0.364
ENSG00000005812 E007 1.0129490 0.032335463 8.785151e-02   13 77015165 77015408 244 - 0.145 0.527 2.571
ENSG00000005812 E008 190.7237023 1.493762734 5.623945e-01 7.449884e-01 13 77015409 77015510 102 - 2.101 2.291 0.638
ENSG00000005812 E009 161.2056473 1.435024499 5.596070e-01 7.430057e-01 13 77015511 77015580 70 - 2.029 2.216 0.626
ENSG00000005812 E010 0.2735028 0.027442404 2.841039e-01   13 77015581 77015581 1 - 0.054 0.251 2.563
ENSG00000005812 E011 167.7716592 1.448568865 5.698757e-01 7.501938e-01 13 77018600 77018722 123 - 2.048 2.226 0.596
ENSG00000005812 E012 0.6002783 0.330002838 6.598917e-01   13 77018723 77018744 22 - 0.142 0.253 1.030
ENSG00000005812 E013 107.9254305 0.014263565 1.556884e-01 3.704563e-01 13 77021513 77021656 144 - 1.892 1.902 0.034
ENSG00000005812 E014 87.0586132 0.003342810 2.645944e-03 2.124248e-02 13 77021657 77021751 95 - 1.808 1.770 -0.128
ENSG00000005812 E015 67.2331668 0.001902372 1.838223e-01 4.088864e-01 13 77021752 77021861 110 - 1.686 1.741 0.186
ENSG00000005812 E016 79.9382912 0.868810132 2.195957e-01 4.529240e-01 13 77026827 77027011 185 - 1.661 2.103 1.489
ENSG00000005812 E017 67.6182350 0.832969502 2.355239e-01 4.714444e-01 13 77027012 77027197 186 - 1.597 2.016 1.417