ENSG00000287737

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000659963 ENSG00000287737 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.311736 1.521974 0.7777845 0.1922848 0.06803248 -0.9595193 0.08991022 0.09686772 0.02698654 0.03539675 0.006905827 -1.5307537 0.07144167 0.0705000 0.03373333 -0.03676667 8.294532e-01 1.754276e-05   FALSE
ENST00000661217 ENSG00000287737 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.311736 1.521974 0.7777845 0.1922848 0.06803248 -0.9595193 0.19288456 0.25477218 0.16673202 0.02696090 0.019687688 -0.5831881 0.15689167 0.1685000 0.21456667 0.04606667 7.639948e-01 1.754276e-05   FALSE
ENST00000667248 ENSG00000287737 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.311736 1.521974 0.7777845 0.1922848 0.06803248 -0.9595193 0.14969499 0.26311819 0.02821304 0.17471312 0.028213040 -2.8373884 0.09822500 0.2017667 0.03843333 -0.16333333 6.388327e-01 1.754276e-05 FALSE FALSE
ENST00000671452 ENSG00000287737 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.311736 1.521974 0.7777845 0.1922848 0.06803248 -0.9595193 0.57569328 0.40636564 0.52162435 0.29559206 0.042733254 0.3525561 0.47373333 0.2292333 0.67573333 0.44650000 1.708402e-01 1.754276e-05   FALSE
ENST00000688894 ENSG00000287737 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.311736 1.521974 0.7777845 0.1922848 0.06803248 -0.9595193 0.28271497 0.50085075 0.00000000 0.10904631 0.000000000 -5.6748300 0.17180833 0.3299333 0.00000000 -0.32993333 1.754276e-05 1.754276e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000287737 E001 1.1844712 0.012199099 0.68109515 0.78489138 17 82273748 82273763 16 + 0.276 0.341 0.425
ENSG00000287737 E002 0.4513240 0.101293171 0.30782905 0.45006243 17 82273764 82273765 2 + 0.276 0.092 -1.907
ENSG00000287737 E003 0.4513240 0.101293171 0.30782905 0.45006243 17 82273766 82273777 12 + 0.276 0.092 -1.907
ENSG00000287737 E004 1.1113191 0.136395477 0.71133950 0.80831785 17 82273778 82273795 18 + 0.276 0.337 0.398
ENSG00000287737 E005 1.5446577 0.013065985 0.09148507 0.17745177 17 82273796 82273830 35 + 0.160 0.463 2.102
ENSG00000287737 E006 3.7556427 0.093895704 0.44693767 0.58838710 17 82273831 82273923 93 + 0.564 0.697 0.577
ENSG00000287737 E007 2.4658414 0.009117865 0.83462172 0.89648463 17 82273924 82273928 5 + 0.508 0.529 0.102
ENSG00000287737 E008 11.0045473 0.001912133 0.52960396 0.66236158 17 82273929 82274281 353 + 1.098 1.023 -0.275
ENSG00000287737 E009 7.8186796 0.002879518 0.87228237 0.92185763 17 82274282 82274483 202 + 0.909 0.912 0.011
ENSG00000287737 E010 12.1668276 0.001606823 0.89828074 0.93911436 17 82274484 82274891 408 + 1.083 1.078 -0.016
ENSG00000287737 E011 6.1581339 0.002868463 0.70272141 0.80151999 17 82274892 82275073 182 + 0.858 0.796 -0.243
ENSG00000287737 E012 23.0083932 0.060696035 0.31565683 0.45842492 17 82275074 82276261 1188 + 1.405 1.309 -0.332
ENSG00000287737 E013 4.0909973 0.004315013 0.01242126 0.03455059 17 82277731 82277886 156 + 0.368 0.761 1.841
ENSG00000287737 E014 0.0000000       17 82277887 82277889 3 +      
ENSG00000287737 E015 0.2214452 0.037744384 0.83681868   17 82277890 82279645 1756 + 0.000 0.093 7.958