ENSG00000286156

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000685339 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.46213561 0.4731784 0.58486763 0.05919207 0.006805861 0.3000126 0.22294167 0.26816667 0.23906667 -0.029100000 0.8406130592 0.0004379729 FALSE TRUE
ENST00000685969 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.25750968 0.0000000 0.32837087 0.00000000 0.091926969 5.0805335 0.10990000 0.00000000 0.13396667 0.133966667 0.0004379729 0.0004379729 FALSE TRUE
ENST00000686539 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.15281991 0.2651612 0.04584291 0.13670783 0.045842905 -2.3008309 0.07618750 0.15740000 0.01846667 -0.138933333 0.4361175413 0.0004379729 TRUE TRUE
ENST00000687639 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.08324969 0.0000000 0.15586928 0.00000000 0.155869281 4.0519748 0.03615833 0.00000000 0.06303333 0.063033333 0.8673380576 0.0004379729 FALSE TRUE
ENST00000690054 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.19542954 0.4162971 0.23981415 0.08035521 0.121755106 -0.7710041 0.10210417 0.23376667 0.09683333 -0.136933333 0.3808020984 0.0004379729 FALSE TRUE
ENST00000690135 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.11062533 0.1163336 0.15633557 0.11633356 0.078241760 0.3968588 0.05299167 0.06116667 0.06313333 0.001966667 0.8331925494 0.0004379729 TRUE TRUE
ENST00000690633 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.25580410 0.0000000 0.27002771 0.00000000 0.270027706 4.8074977 0.11107083 0.00000000 0.11296667 0.112966667 0.8832899385 0.0004379729 FALSE TRUE
ENST00000690934 ENSG00000286156 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene processed_transcript 2.117954 1.754572 2.447548 0.1434604 0.02885206 0.4779011 0.33914004 0.3337201 0.46163712 0.02527688 0.056225537 0.4564429 0.16052083 0.19040000 0.18853333 -0.001866667 1.0000000000 0.0004379729   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000286156 E001 5.2606100 0.003310511 0.042436695 0.095515083 2 94193659 94194936 1278 - 0.646 0.910 1.058
ENSG00000286156 E002 1.9218596 0.009335558 0.293731453 0.434782771 2 94194937 94195291 355 - 0.351 0.529 0.935
ENSG00000286156 E003 1.0245247 0.015378759 0.909908966 0.946724099 2 94195292 94195440 149 - 0.287 0.306 0.129
ENSG00000286156 E004 0.6579068 0.397131374 0.905864513 0.944139004 2 94195441 94195442 2 - 0.210 0.227 0.139
ENSG00000286156 E005 0.8030795 0.132057575 0.765105997 0.847950928 2 94195443 94195663 221 - 0.286 0.226 -0.453
ENSG00000286156 E006 0.0000000       2 94195664 94195799 136 -      
ENSG00000286156 E007 0.0000000       2 94195800 94195805 6 -      
ENSG00000286156 E008 0.0000000       2 94195806 94195807 2 -      
ENSG00000286156 E009 0.0000000       2 94195808 94195809 2 -      
ENSG00000286156 E010 0.0000000       2 94195810 94195810 1 -      
ENSG00000286156 E011 0.0000000       2 94195811 94195812 2 -      
ENSG00000286156 E012 0.1472490 0.042535225 0.537720507   2 94195813 94195855 43 - 0.118 0.000 -12.836
ENSG00000286156 E013 2.7732273 0.013348563 0.945341598 0.969679952 2 94195856 94195927 72 - 0.580 0.571 -0.044
ENSG00000286156 E014 2.7732273 0.013348563 0.945341598 0.969679952 2 94195928 94195932 5 - 0.580 0.571 -0.044
ENSG00000286156 E015 5.2746344 0.003405701 0.324261062 0.467626976 2 94195933 94196056 124 - 0.859 0.734 -0.495
ENSG00000286156 E016 4.4953891 0.003856450 0.194638599 0.319543295 2 94196057 94196188 132 - 0.820 0.644 -0.721
ENSG00000286156 E017 3.0665820 0.005746056 0.104916630 0.197971230 2 94196189 94196229 41 - 0.729 0.483 -1.097
ENSG00000286156 E018 2.0324909 0.107183062 0.603368320 0.724172715 2 94196230 94196230 1 - 0.544 0.429 -0.564
ENSG00000286156 E019 0.1515154 0.043761891 0.536133543   2 94196231 94196572 342 - 0.118 0.000 -12.835
ENSG00000286156 E020 0.0000000       2 94196573 94196720 148 -      
ENSG00000286156 E021 3.7568376 0.005395860 0.287998118 0.428541578 2 94196721 94197635 915 - 0.580 0.734 0.658
ENSG00000286156 E022 2.1776636 0.010708828 0.367290248 0.511655188 2 94197636 94197666 31 - 0.580 0.431 -0.723
ENSG00000286156 E023 3.4707732 0.004792576 0.395807695 0.539597165 2 94197667 94197758 92 - 0.580 0.706 0.541
ENSG00000286156 E024 3.3642961 0.048790363 0.184758814 0.307172534 2 94197759 94198669 911 - 0.503 0.733 1.017
ENSG00000286156 E025 0.2934659 0.029063616 0.960152799   2 94198670 94198671 2 - 0.118 0.127 0.124
ENSG00000286156 E026 0.2934659 0.029063616 0.960152799   2 94198672 94198672 1 - 0.118 0.127 0.124
ENSG00000286156 E027 0.4449813 0.023541665 0.618340634 0.736006396 2 94198673 94198744 72 - 0.210 0.127 -0.876
ENSG00000286156 E028 0.6330284 0.050129470 0.938924636 0.965651878 2 94198745 94198880 136 - 0.210 0.225 0.122
ENSG00000286156 E029 0.9630260 0.050726153 0.382458425 0.526666385 2 94198881 94198922 42 - 0.210 0.372 1.119
ENSG00000286156 E030 0.6330284 0.050129470 0.938924636 0.965651878 2 94198923 94198939 17 - 0.210 0.225 0.122
ENSG00000286156 E031 0.4815130 0.022104886 0.520530367 0.654487340 2 94198940 94198980 41 - 0.118 0.225 1.125
ENSG00000286156 E032 0.7813216 0.032138535 0.604143435 0.724772420 2 94198981 94199121 141 - 0.210 0.305 0.706
ENSG00000286156 E033 0.4513240 0.205394205 0.653714519 0.764102805 2 94199122 94199124 3 - 0.211 0.126 -0.894
ENSG00000286156 E034 0.4513240 0.205394205 0.653714519 0.764102805 2 94199125 94199126 2 - 0.211 0.126 -0.894
ENSG00000286156 E035 2.2582014 0.007773058 0.496998317 0.633570017 2 94199127 94199185 59 - 0.458 0.570 0.540
ENSG00000286156 E036 10.0423489 0.002394124 0.001115372 0.004354805 2 94199186 94199366 181 - 0.840 1.174 1.235
ENSG00000286156 E037 0.5931727 0.517305797 0.181128457 0.302634765 2 94199367 94199392 26 - 0.000 0.355 13.662
ENSG00000286156 E038 0.4448795 0.308650307 0.160928926 0.276335131 2 94199393 94199450 58 - 0.000 0.296 13.494
ENSG00000286156 E039 9.8205305 0.101877648 0.400374268 0.544072591 2 94199451 94199568 118 - 0.961 1.087 0.465
ENSG00000286156 E040 7.6259082 0.035847365 0.559654013 0.687735698 2 94199569 94199639 71 - 0.974 0.892 -0.307
ENSG00000286156 E041 0.3030308 0.413418854 0.332883590   2 94199640 94199674 35 - 0.211 0.000 -13.421
ENSG00000286156 E042 0.2934659 0.029063616 0.960152799   2 94200722 94200780 59 - 0.118 0.127 0.124
ENSG00000286156 E043 0.2966881 0.030329124 0.228196342   2 94200781 94200844 64 - 0.210 0.000 -13.646
ENSG00000286156 E044 0.8836184 0.024322416 0.584780751 0.708617322 2 94201820 94202043 224 - 0.210 0.306 0.714
ENSG00000286156 E045 9.6593672 0.014118790 0.221431391 0.352130173 2 94202397 94202568 172 - 1.087 0.947 -0.513
ENSG00000286156 E046 4.8890770 0.033810876 0.123022622 0.224266918 2 94203214 94203287 74 - 0.877 0.644 -0.941
ENSG00000286156 E047 0.4386386 0.198621254 0.647013460 0.758779506 2 94203288 94203407 120 - 0.210 0.126 -0.887
ENSG00000286156 E048 0.1515154 0.043761891 0.536133543   2 94207808 94207921 114 - 0.118 0.000 -12.835
ENSG00000286156 E049 0.1515154 0.043761891 0.536133543   2 94207922 94208122 201 - 0.118 0.000 -12.835
ENSG00000286156 E050 0.0000000       2 94208123 94208232 110 -      
ENSG00000286156 E051 0.0000000       2 94208233 94208307 75 -      
ENSG00000286156 E052 0.0000000       2 94208308 94208309 2 -      
ENSG00000286156 E053 2.7948729 0.005746056 0.212922700 0.341977098 2 94208310 94208312 3 - 0.676 0.483 -0.874
ENSG00000286156 E054 2.4950643 0.008459783 0.182269381 0.304047648 2 94208313 94208315 3 - 0.646 0.431 -1.011
ENSG00000286156 E055 2.2736191 0.015904858 0.101266093 0.192399686 2 94208316 94208317 2 - 0.646 0.373 -1.335
ENSG00000286156 E056 1.8296820 0.072636214 0.370815643 0.515228873 2 94208318 94208328 11 - 0.542 0.371 -0.880
ENSG00000286156 E057 1.6479776 0.070626378 0.209449601 0.337879873 2 94208329 94208330 2 - 0.543 0.304 -1.296
ENSG00000286156 E058 1.5028049 0.031914991 0.270097845 0.408680307 2 94208331 94208334 4 - 0.502 0.305 -1.100
ENSG00000286156 E059 1.3920876 0.012440993 0.837923503 0.898670716 2 94208335 94208342 8 - 0.408 0.373 -0.197
ENSG00000286156 E060 1.2103832 0.012384699 0.556943280 0.685480620 2 94208343 94208350 8 - 0.408 0.305 -0.612
ENSG00000286156 E061 0.9179615 0.014308081 0.920440549 0.953784518 2 94208351 94208364 14 - 0.287 0.305 0.124
ENSG00000286156 E062 0.4772466 0.021768165 0.518827609 0.652979113 2 94208365 94208367 3 - 0.118 0.225 1.125
ENSG00000286156 E063 0.4772466 0.021768165 0.518827609 0.652979113 2 94208368 94208371 4 - 0.118 0.225 1.125
ENSG00000286156 E064 0.4772466 0.021768165 0.518827609 0.652979113 2 94208372 94208376 5 - 0.118 0.225 1.125
ENSG00000286156 E065 0.4772466 0.021768165 0.518827609 0.652979113 2 94208377 94208378 2 - 0.118 0.225 1.125
ENSG00000286156 E066 0.4772466 0.021768165 0.518827609 0.652979113 2 94208379 94208379 1 - 0.118 0.225 1.125
ENSG00000286156 E067 0.4772466 0.021768165 0.518827609 0.652979113 2 94208380 94208381 2 - 0.118 0.225 1.125
ENSG00000286156 E068 0.4772466 0.021768165 0.518827609 0.652979113 2 94208382 94208385 4 - 0.118 0.225 1.125
ENSG00000286156 E069 0.4772466 0.021768165 0.518827609 0.652979113 2 94208386 94208387 2 - 0.118 0.225 1.125
ENSG00000286156 E070 0.4772466 0.021768165 0.518827609 0.652979113 2 94208388 94208390 3 - 0.118 0.225 1.125
ENSG00000286156 E071 0.4772466 0.021768165 0.518827609 0.652979113 2 94208391 94208396 6 - 0.118 0.225 1.125
ENSG00000286156 E072 0.4772466 0.021768165 0.518827609 0.652979113 2 94208397 94208400 4 - 0.118 0.225 1.125
ENSG00000286156 E073 0.3289534 0.028465923 0.948902511   2 94208401 94208408 8 - 0.118 0.127 0.127