ENSG00000282381

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000632111 ENSG00000282381 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 2.487427 1.06615 3.9351 0.1875963 0.4555593 1.874183 0.4218982 0.05048973 1.1140742 0.05048973 0.1266642 4.2159031 0.14496667 0.03543333 0.2998667 0.26443333 0.0175233845 0.0006501276 FALSE FALSE
ENST00000687368 ENSG00000282381 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 2.487427 1.06615 3.9351 0.1875963 0.4555593 1.874183 0.5801309 0.52739765 0.5687044 0.10743899 0.1449405 0.1068366 0.28317500 0.48963333 0.1471000 -0.34253333 0.0006501276 0.0006501276 TRUE FALSE
MSTRG.29932.1 ENSG00000282381 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   2.487427 1.06615 3.9351 0.1875963 0.4555593 1.874183 0.2142531 0.00000000 0.2067007 0.00000000 0.1094598 4.4376320 0.08079167 0.00000000 0.0469000 0.04690000 0.4437271247 0.0006501276 TRUE FALSE
MSTRG.29932.5 ENSG00000282381 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   2.487427 1.06615 3.9351 0.1875963 0.4555593 1.874183 0.4169143 0.00000000 0.5578896 0.00000000 0.3003395 5.8275386 0.12105417 0.00000000 0.1285667 0.12856667 0.3785905426 0.0006501276 FALSE FALSE
MSTRG.29932.6 ENSG00000282381 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   2.487427 1.06615 3.9351 0.1875963 0.4555593 1.874183 0.8542307 0.48826218 1.4877307 0.03274542 0.1814445 1.5878013 0.37002500 0.47493333 0.3775667 -0.09736667 0.5287666696 0.0006501276   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000282381 E001 0.1515154 0.042334693 1.0000000000   7 65269359 65269373 15 + 0.084 0.000 -9.202
ENSG00000282381 E002 0.8942170 0.013809474 0.0867802617 0.170252477 7 65269374 65269388 15 + 0.358 0.000 -11.787
ENSG00000282381 E003 1.1876829 0.010916502 0.2715523556 0.410327251 7 65269389 65269391 3 + 0.397 0.175 -1.589
ENSG00000282381 E004 8.0712014 0.002410563 0.0147092818 0.039834598 7 65269392 65269538 147 + 1.025 0.697 -1.272
ENSG00000282381 E005 12.2344160 0.001703013 0.0629561154 0.131638603 7 65303529 65303802 274 + 1.159 0.952 -0.757
ENSG00000282381 E006 2.3838866 0.007243862 0.0017908502 0.006570185 7 65306080 65306238 159 + 0.645 0.000 -13.202
ENSG00000282381 E007 3.6996991 0.004457885 0.6697014643 0.776394371 7 65306469 65306503 35 + 0.685 0.600 -0.366
ENSG00000282381 E008 6.4804943 0.002743169 0.0224970967 0.056715604 7 65308002 65308202 201 + 0.938 0.600 -1.365
ENSG00000282381 E009 9.2300832 0.017126774 0.9241485326 0.956230328 7 65309397 65309584 188 + 0.989 0.976 -0.045
ENSG00000282381 E010 14.2619389 0.001793752 0.0492461953 0.107824836 7 65313570 65313753 184 + 1.097 1.241 0.511
ENSG00000282381 E011 0.0000000       7 65313754 65313902 149 +      
ENSG00000282381 E012 12.3933080 0.001568192 0.0631889717 0.132018784 7 65317447 65317566 120 + 1.042 1.188 0.524
ENSG00000282381 E013 7.1350537 0.003038917 0.0003233767 0.001474363 7 65317567 65317938 372 + 0.703 1.095 1.497
ENSG00000282381 E014 3.5984319 0.004990765 0.5352485037 0.667149578 7 65338532 65338616 85 + 0.623 0.696 0.312
ENSG00000282381 E015 1.8467330 0.008456051 0.2447962924 0.379797417 7 65350059 65350100 42 + 0.358 0.542 0.958
ENSG00000282381 E016 0.6653823 0.017418135 0.8786442398 0.926044591 7 65373150 65373226 77 + 0.215 0.175 -0.363