ENSG00000280739

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000625390 ENSG00000280739 HEK293_OSMI2_2hA HEK293_TMG_2hB EIF1B-AS1 lncRNA lncRNA 1.674687 1.861734 1.80317 0.1571019 0.09241896 -0.04586134 0.18484774 0.19548679 0.17454890 0.075274479 0.02984102 -0.1550426 0.11362500 0.10020000 0.09800000 -0.00220000 0.91561258 0.02678302   FALSE
ENST00000629723 ENSG00000280739 HEK293_OSMI2_2hA HEK293_TMG_2hB EIF1B-AS1 lncRNA lncRNA 1.674687 1.861734 1.80317 0.1571019 0.09241896 -0.04586134 0.13244519 0.11826020 0.15349971 0.006922661 0.03539371 0.3502145 0.08110000 0.06500000 0.08616667 0.02116667 0.82198828 0.02678302   FALSE
ENST00000631175 ENSG00000280739 HEK293_OSMI2_2hA HEK293_TMG_2hB EIF1B-AS1 lncRNA lncRNA 1.674687 1.861734 1.80317 0.1571019 0.09241896 -0.04586134 0.39637264 0.31509912 0.37232658 0.047822858 0.02539910 0.2339258 0.25313333 0.17150000 0.20643333 0.03493333 0.75084660 0.02678302 FALSE TRUE
ENST00000657703 ENSG00000280739 HEK293_OSMI2_2hA HEK293_TMG_2hB EIF1B-AS1 lncRNA lncRNA 1.674687 1.861734 1.80317 0.1571019 0.09241896 -0.04586134 0.09157679 0.06798208 0.09715451 0.024120024 0.04934021 0.4584780 0.06091667 0.03853333 0.05123333 0.01270000 0.90499812 0.02678302 FALSE FALSE
ENST00000688606 ENSG00000280739 HEK293_OSMI2_2hA HEK293_TMG_2hB EIF1B-AS1 lncRNA lncRNA 1.674687 1.861734 1.80317 0.1571019 0.09241896 -0.04586134 0.61522945 1.00646769 0.59861537 0.091999108 0.05094468 -0.7399617 0.33506667 0.54086667 0.33236667 -0.20850000 0.02678302 0.02678302   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000280739 E001 1.1696989 0.379638188 0.316770066 0.45956600 3 40061110 40062432 1323 - 0.483 0.203 -1.770
ENSG00000280739 E002 0.5149111 0.021936661 0.611042781 0.73024704 3 40065399 40065575 177 - 0.128 0.209 0.857
ENSG00000280739 E003 0.0000000       3 40081089 40083687 2599 -      
ENSG00000280739 E004 0.5848540 0.165987709 0.108891865 0.20390666 3 40083688 40083772 85 - 0.000 0.288 11.377
ENSG00000280739 E005 1.4265429 0.033350381 0.821864605 0.88767900 3 40117544 40117736 193 - 0.374 0.406 0.175
ENSG00000280739 E006 8.5622524 0.042805372 0.515402765 0.65007819 3 40173145 40174722 1578 - 0.930 1.028 0.364
ENSG00000280739 E007 0.7426990 0.054627279 0.355636189 0.50000897 3 40184378 40184401 24 - 0.128 0.286 1.447
ENSG00000280739 E008 7.4072247 0.006565497 0.113774286 0.21102602 3 40184402 40184585 184 - 0.811 0.985 0.664
ENSG00000280739 E009 0.0000000       3 40184586 40186349 1764 -      
ENSG00000280739 E010 0.4502799 0.039978216 0.077299386 0.15515651 3 40232857 40233059 203 - 0.307 0.000 -12.769
ENSG00000280739 E011 1.3222570 0.011186365 0.921246756 0.95430472 3 40239568 40242486 2919 - 0.374 0.350 -0.143
ENSG00000280739 E012 0.0000000       3 40244452 40244456 5 -      
ENSG00000280739 E013 0.0000000       3 40244457 40244638 182 -      
ENSG00000280739 E014 0.1472490 0.043114683 0.467779246   3 40246819 40246829 11 - 0.128 0.000 -11.462
ENSG00000280739 E015 3.6994836 0.019060343 0.080320885 0.16006807 3 40246830 40248183 1354 - 0.811 0.540 -1.149
ENSG00000280739 E016 1.7465006 0.067427876 0.143937095 0.25337481 3 40248184 40248471 288 - 0.573 0.286 -1.559
ENSG00000280739 E017 8.2742882 0.002628180 0.678073402 0.78262786 3 40289128 40291227 2100 - 0.995 0.941 -0.201
ENSG00000280739 E018 4.8921088 0.004059470 0.263498969 0.40141438 3 40292550 40294924 2375 - 0.855 0.701 -0.614
ENSG00000280739 E019 0.3299976 0.027442404 0.219272224   3 40299069 40300048 980 - 0.000 0.209 11.024
ENSG00000280739 E020 19.0943614 0.001156966 0.367570358 0.51193623 3 40301237 40301396 160 - 1.274 1.325 0.177
ENSG00000280739 E021 1.0246279 0.162996996 0.009926176 0.02857966 3 40308818 40309073 256 - 0.530 0.000 -13.511
ENSG00000280739 E022 0.8814298 0.016231458 0.361938080 0.50634378 3 40309074 40309322 249 - 0.374 0.209 -1.146
ENSG00000280739 E023 7.4875663 0.002467490 0.726082908 0.81919940 3 40309323 40309327 5 - 0.913 0.941 0.107
ENSG00000280739 E024 12.5867216 0.001556997 0.615723945 0.73392469 3 40309328 40309698 371 - 1.113 1.146 0.119