ENSG00000273763

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000620999 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene transcribed_processed_pseudogene 1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.1543531 0.00000000 0.51805897 0.00000000 0.08102771 5.722627 0.10464167 0.00000000 0.30106667 0.3010667 9.114285e-08 9.114285e-08   FALSE
ENST00000650256 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene processed_transcript 1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.1475912 0.19173125 0.05278390 0.19173125 0.05278390 -1.683968 0.16155000 0.17566667 0.03510000 -0.1405667 9.207461e-01 9.114285e-08 FALSE FALSE
ENST00000688491 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene processed_transcript 1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.1339039 0.25385890 0.08525909 0.15073008 0.08525909 -1.469838 0.10906250 0.22926667 0.04983333 -0.1794333 5.481622e-01 9.114285e-08 FALSE FALSE
ENST00000691402 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene processed_transcript 1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.4113835 0.47918007 0.21033484 0.10936090 0.05516252 -1.150668 0.36787083 0.43316667 0.12800000 -0.3051667 3.126927e-02 9.114285e-08 FALSE FALSE
MSTRG.18540.4 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene   1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.2613383 0.06549651 0.54610457 0.06549651 0.35030701 2.880874 0.17157917 0.05946667 0.30833333 0.2488667 5.776164e-01 9.114285e-08 FALSE FALSE
MSTRG.18540.5 ENSG00000273763 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_processed_pseudogene   1.238855 1.104382 1.703167 0.00841084 0.1129585 0.6204223 0.1302855 0.11411495 0.29062551 0.06728880 0.16782909 1.276291 0.08528333 0.10243333 0.17763333 0.0752000 9.072260e-01 9.114285e-08 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000273763 E001 0.9544932 0.063961197 0.58709865 0.7104745 2 65203502 65203570 69 - 0.234 0.338 0.722
ENSG00000273763 E002 20.1892361 0.001724499 0.05525751 0.1184339 2 65203571 65204974 1404 - 1.378 1.280 -0.340
ENSG00000273763 E003 1.2199456 0.011393115 0.38887637 0.5329629 2 65204975 65204975 1 - 0.234 0.395 1.052
ENSG00000273763 E004 2.0377858 0.008425126 0.16390468 0.2802390 2 65204976 65204980 5 - 0.316 0.564 1.314
ENSG00000273763 E005 5.3978035 0.004433786 0.41626965 0.5596392 2 65204981 65205312 332 - 0.723 0.841 0.467
ENSG00000273763 E006 4.7190113 0.004757447 0.04993551 0.1090556 2 65207079 65207196 118 - 0.871 0.630 -0.979
ENSG00000273763 E007 0.8115992 0.017442567 0.48456887 0.6225256 2 65222467 65222540 74 - 0.316 0.202 -0.855
ENSG00000273763 E008 8.1034881 0.062119186 0.03753867 0.0864799 2 65226616 65227427 812 - 0.752 1.060 1.174
ENSG00000273763 E009 3.9398017 0.068662950 0.89480006 0.9367609 2 65227428 65227484 57 - 0.660 0.691 0.128
ENSG00000273763 E010 5.6777814 0.003619167 0.75121001 0.8377058 2 65227485 65227661 177 - 0.827 0.802 -0.099