ENSG00000271913

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000657923 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.03177041 0.08567053 0.005267684 0.01271092 0.005267684 -2.64759339 0.01955417 0.05613333 0.003733333 -0.0524000000 0.04154798 0.04154798    
ENST00000659171 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.48986477 0.62412821 0.776946554 0.17636182 0.264189172 0.31149109 0.29627500 0.39400000 0.393533333 -0.0004666667 0.99612696 0.04154798 FALSE  
ENST00000663014 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.26724844 0.09900767 0.147043041 0.06286548 0.017609274 0.52673035 0.14266250 0.05853333 0.074600000 0.0160666667 0.85373601 0.04154798 FALSE  
ENST00000665423 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.14057350 0.08069796 0.148764714 0.04321645 0.010418163 0.80774828 0.07866667 0.05076667 0.076733333 0.0259666667 0.80539045 0.04154798    
ENST00000667828 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.18112858 0.19847877 0.166222895 0.09950122 0.166222895 -0.24249909 0.12184167 0.13676667 0.077066667 -0.0597000000 0.63869987 0.04154798 FALSE  
ENST00000685651 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA lncRNA 1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.11213239 0.13891889 0.208730569 0.09413178 0.047643311 0.55462810 0.06639167 0.08203333 0.115766667 0.0337333333 0.82407199 0.04154798 FALSE  
MSTRG.29268.9 ENSG00000271913 HEK293_OSMI2_2hA HEK293_TMG_2hB TAGAP-AS1 lncRNA   1.707477 1.555589 2.042267 0.1119621 0.333403 0.390513 0.25760308 0.19671043 0.202886383 0.19671043 0.202886383 0.04247246 0.13350000 0.12890000 0.079433333 -0.0494666667 1.00000000 0.04154798 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000271913 E001 0.0000000       6 158988178 158988276 99 +      
ENSG00000271913 E002 0.0000000       6 158990436 158990572 137 +      
ENSG00000271913 E003 0.0000000       6 158999832 158999860 29 +      
ENSG00000271913 E004 0.0000000       6 158999861 158999862 2 +      
ENSG00000271913 E005 0.0000000       6 158999863 158999881 19 +      
ENSG00000271913 E006 0.4460135 0.022667184 0.089615923 0.17454140 6 158999882 158999885 4 + 0.293 0.000 -11.755
ENSG00000271913 E007 4.4295077 0.003995854 0.774901669 0.85495109 6 158999886 158999910 25 + 0.714 0.749 0.144
ENSG00000271913 E008 0.1817044 0.039585961 0.478161794   6 158999913 158999922 10 + 0.000 0.124 12.050
ENSG00000271913 E009 0.1817044 0.039585961 0.478161794   6 158999923 158999924 2 + 0.000 0.124 12.050
ENSG00000271913 E010 0.1817044 0.039585961 0.478161794   6 158999925 158999937 13 + 0.000 0.124 12.050
ENSG00000271913 E011 3.2000233 0.141028692 0.983767318 0.99393065 6 158999938 159000093 156 + 0.625 0.630 0.022
ENSG00000271913 E012 3.0475629 0.008887960 0.593453546 0.71584654 6 159000094 159000115 22 + 0.553 0.634 0.361
ENSG00000271913 E013 2.5724046 0.006955383 0.175085385 0.29479457 6 159000116 159000118 3 + 0.416 0.633 1.038
ENSG00000271913 E014 4.6780475 0.031057559 0.670458207 0.77688748 6 159000119 159000190 72 + 0.714 0.776 0.248
ENSG00000271913 E015 4.3168289 0.004009323 0.929400818 0.95958466 6 159000191 159000232 42 + 0.714 0.723 0.037
ENSG00000271913 E016 2.9151763 0.005746056 0.425312347 0.56825595 6 159000233 159000234 2 + 0.512 0.633 0.553
ENSG00000271913 E017 3.0269509 0.012240560 0.594563811 0.71677504 6 159000235 159000243 9 + 0.553 0.633 0.360
ENSG00000271913 E018 3.2086553 0.032306959 0.485963907 0.62378484 6 159000244 159000257 14 + 0.553 0.666 0.500
ENSG00000271913 E019 4.2781442 0.044784386 0.286067982 0.42645138 6 159000258 159000309 52 + 0.625 0.796 0.708
ENSG00000271913 E020 5.4272045 0.003662849 0.787493017 0.86390775 6 159000310 159000392 83 + 0.788 0.820 0.124
ENSG00000271913 E021 1.1081736 0.012087273 0.273478915 0.41252108 6 159020085 159020390 306 + 0.416 0.220 -1.285
ENSG00000271913 E022 2.3680886 0.069008615 0.370482772 0.51490987 6 159023603 159023941 339 + 0.590 0.427 -0.791
ENSG00000271913 E023 11.0338523 0.014438034 0.048291956 0.10614649 6 159023942 159025945 2004 + 0.940 1.154 0.783
ENSG00000271913 E024 1.4370503 0.042079012 0.095215276 0.18319824 6 159025946 159025948 3 + 0.216 0.517 1.833
ENSG00000271913 E025 12.4236940 0.001703013 0.697090535 0.79730077 6 159025949 159026041 93 + 1.110 1.142 0.113
ENSG00000271913 E026 14.0391312 0.001525403 0.238011353 0.37183472 6 159027144 159027230 87 + 1.224 1.121 -0.368
ENSG00000271913 E027 27.6688735 0.030257460 0.846273845 0.90443655 6 159027231 159028354 1124 + 1.462 1.446 -0.054
ENSG00000271913 E028 0.1482932 0.044352564 0.477861585   6 159040731 159040790 60 + 0.000 0.123 12.042
ENSG00000271913 E029 0.4427912 0.154460044 0.632225655 0.74711047 6 159040791 159040918 128 + 0.215 0.123 -0.975
ENSG00000271913 E030 1.1146155 0.327611290 0.976339317 0.98921577 6 159040919 159041055 137 + 0.294 0.311 0.112
ENSG00000271913 E031 0.2214452 0.039915884 0.476711989   6 159041056 159041797 742 + 0.000 0.124 12.052
ENSG00000271913 E032 6.3413565 0.005017345 0.144057766 0.25352834 6 159041798 159042308 511 + 0.956 0.774 -0.702
ENSG00000271913 E033 1.5553330 0.009055898 0.008297999 0.02453883 6 159042309 159042522 214 + 0.590 0.124 -3.132
ENSG00000271913 E034 0.8491631 0.014581546 0.686718726 0.78917508 6 159042523 159042676 154 + 0.293 0.220 -0.546
ENSG00000271913 E035 0.4783925 0.022195237 0.584463704 0.70837920 6 159042677 159042797 121 + 0.216 0.124 -0.963
ENSG00000271913 E036 5.5829769 0.003585761 0.075224188 0.15189125 6 159042798 159044618 1821 + 0.924 0.695 -0.902
ENSG00000271913 E037 4.3599667 0.153629579 0.616749665 0.73474133 6 159047674 159048736 1063 + 0.741 0.684 -0.232
ENSG00000271913 E038 0.0000000       6 159064879 159064925 47 +      
ENSG00000271913 E039 0.1472490 0.042643487 0.499687297   6 159067239 159067880 642 + 0.121 0.000 -12.995
ENSG00000271913 E040 0.0000000       6 159067881 159067950 70 +      
ENSG00000271913 E041 0.1451727 0.057827934 0.497516690   6 159068675 159069102 428 + 0.121 0.000 -12.978
ENSG00000271913 E042 0.1451727 0.057827934 0.497516690   6 159075880 159076955 1076 + 0.121 0.000 -12.978
ENSG00000271913 E043 0.1515154 0.041953976 0.499802594   6 159086553 159088114 1562 + 0.121 0.000 -12.997