ENSG00000264247

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000580048 ENSG00000264247 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF407-AS1 lncRNA lncRNA 3.345115 2.096024 4.895454 0.03300753 0.2712012 1.219865 0.2003682 0.00000000 0.3297897 0.00000000 0.1015835 5.0865703 0.04561667 0.00000000 0.0657000 0.06570000 0.005035758 0.005035758 TRUE FALSE
ENST00000585279 ENSG00000264247 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF407-AS1 lncRNA lncRNA 3.345115 2.096024 4.895454 0.03300753 0.2712012 1.219865 0.1525392 0.05452211 0.4405829 0.05452211 0.2204239 2.8039269 0.03853333 0.02526667 0.0947000 0.06943333 0.669654311 0.005035758   FALSE
ENST00000652782 ENSG00000264247 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF407-AS1 lncRNA lncRNA 3.345115 2.096024 4.895454 0.03300753 0.2712012 1.219865 2.2992580 1.67908201 3.0737892 0.10303521 0.2702678 0.8684648 0.68234583 0.80030000 0.6268667 -0.17343333 0.077116328 0.005035758 TRUE FALSE
ENST00000657978 ENSG00000264247 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF407-AS1 lncRNA lncRNA 3.345115 2.096024 4.895454 0.03300753 0.2712012 1.219865 0.1189251 0.00000000 0.0000000 0.00000000 0.0000000 0.0000000 0.05331250 0.00000000 0.0000000 0.00000000   0.005035758   FALSE
ENST00000664604 ENSG00000264247 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF407-AS1 lncRNA lncRNA 3.345115 2.096024 4.895454 0.03300753 0.2712012 1.219865 0.3943237 0.20112211 0.8189867 0.12558254 0.1471153 1.9732712 0.11812083 0.09710000 0.1653333 0.06823333 0.599769924 0.005035758   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000264247 E001 0.6287620 0.0172671820 0.54442333 0.67489426 18 74590317 74591668 1352 - 0.170 0.275 0.887
ENSG00000264247 E002 0.2955422 0.0297046002 0.65342752   18 74591669 74591773 105 - 0.093 0.159 0.886
ENSG00000264247 E003 0.1482932 0.0414049366 0.26643674   18 74591774 74591820 47 - 0.000 0.159 10.611
ENSG00000264247 E004 7.1633895 0.0024011347 0.38838351 0.53246192 18 74591821 74592827 1007 - 0.937 0.830 -0.411
ENSG00000264247 E005 1.4918596 0.0738907008 0.01160297 0.03258977 18 74592828 74592839 12 - 0.531 0.000 -12.437
ENSG00000264247 E006 34.9938393 0.0006439889 0.92091319 0.95411250 18 74592840 74593148 309 - 1.547 1.551 0.013
ENSG00000264247 E007 22.8293833 0.0009015680 0.99777503 1.00000000 18 74593149 74593200 52 - 1.366 1.364 -0.007
ENSG00000264247 E008 58.9117407 0.0004326143 0.88688458 0.93167141 18 74593201 74593623 423 - 1.766 1.771 0.015
ENSG00000264247 E009 24.1958163 0.0010880962 0.61265015 0.73153116 18 74593624 74593695 72 - 1.409 1.372 -0.127
ENSG00000264247 E010 30.1427958 0.0007642473 0.57715993 0.70246094 18 74593696 74593839 144 - 1.503 1.467 -0.124
ENSG00000264247 E011 23.4399992 0.0128573051 0.81867801 0.88541845 18 74596428 74596582 155 - 1.371 1.389 0.064
ENSG00000264247 E012 56.7874653 0.0030019755 0.53356897 0.66574180 18 74596583 74597257 675 - 1.739 1.765 0.089
ENSG00000264247 E013 31.0889243 0.0006587716 0.37146218 0.51590774 18 74597258 74597735 478 - 1.476 1.528 0.179
ENSG00000264247 E014 8.0999628 0.0293971345 0.90218476 0.94167146 18 74597736 74597842 107 - 0.949 0.970 0.077
ENSG00000264247 E015 3.5503486 0.0043854955 0.06287968 0.13150922 18 74598230 74598583 354 - 0.744 0.443 -1.360
ENSG00000264247 E016 0.0000000       18 74598760 74598885 126 -