ENSG00000260083

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000565573 ENSG00000260083 HEK293_OSMI2_2hA HEK293_TMG_2hB MIR762HG lncRNA lncRNA 3.010355 3.605012 3.266556 0.2764759 0.4863262 -0.1418201 0.1434347 0.1156450 0.24576533 0.06417604 0.12476408 1.0254678 0.04592083 0.03003333 0.08760000 0.05756667 0.81285087 0.02510904 FALSE FALSE
ENST00000570025 ENSG00000260083 HEK293_OSMI2_2hA HEK293_TMG_2hB MIR762HG lncRNA lncRNA 3.010355 3.605012 3.266556 0.2764759 0.4863262 -0.1418201 0.7354096 1.4122864 0.08499895 0.55537182 0.04252445 -3.9041565 0.24168333 0.42083333 0.02410000 -0.39673333 0.02510904 0.02510904 TRUE FALSE
ENST00000658747 ENSG00000260083 HEK293_OSMI2_2hA HEK293_TMG_2hB MIR762HG lncRNA lncRNA 3.010355 3.605012 3.266556 0.2764759 0.4863262 -0.1418201 0.7764344 0.8496688 0.66681027 0.29368255 0.31093492 -0.3450295 0.25272500 0.22656667 0.18556667 -0.04100000 0.88516608 0.02510904   FALSE
ENST00000662645 ENSG00000260083 HEK293_OSMI2_2hA HEK293_TMG_2hB MIR762HG lncRNA lncRNA 3.010355 3.605012 3.266556 0.2764759 0.4863262 -0.1418201 0.1969884 0.1125592 0.31308971 0.05706584 0.18044927 1.3984559 0.06950833 0.03360000 0.08516667 0.05156667 0.51704977 0.02510904   FALSE
ENST00000663816 ENSG00000260083 HEK293_OSMI2_2hA HEK293_TMG_2hB MIR762HG lncRNA lncRNA 3.010355 3.605012 3.266556 0.2764759 0.4863262 -0.1418201 1.0234128 1.0864198 1.91180971 0.55444824 0.12996658 0.8096652 0.34128333 0.27966667 0.60700000 0.32733333 0.48766090 0.02510904   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000260083 E001 6.4198197 0.1260618964 5.283033e-02 1.141848e-01 16 30875222 30875407 186 + 0.565 0.965 1.623
ENSG00000260083 E002 6.5796527 0.0027237920 5.522489e-04 2.355341e-03 16 30875408 30875460 53 + 0.517 0.995 1.954
ENSG00000260083 E003 5.4424110 0.0031337134 2.142932e-03 7.668676e-03 16 30875461 30875461 1 + 0.464 0.915 1.918
ENSG00000260083 E004 13.7485025 0.0015167634 3.755196e-05 2.179233e-04 16 30875462 30875486 25 + 0.852 1.267 1.517
ENSG00000260083 E005 36.4275140 0.0008021709 4.581555e-05 2.605944e-04 16 30875487 30875778 292 + 1.392 1.630 0.814
ENSG00000260083 E006 20.5776358 0.0011265943 4.365381e-08 4.764518e-07 16 30875779 30876029 251 + 1.514 1.130 -1.344
ENSG00000260083 E007 11.7336872 0.0017242950 4.049215e-03 1.327873e-02 16 30876030 30876081 52 + 1.231 0.970 -0.946
ENSG00000260083 E008 11.9270474 0.0020400804 8.287530e-04 3.361915e-03 16 30876082 30876118 37 + 1.260 0.956 -1.095
ENSG00000260083 E009 0.1482932 0.0413964153 6.587681e-01   16 30888122 30888216 95 + 0.000 0.106 8.692
ENSG00000260083 E010 2.5923385 0.1155362437 9.024108e-01 9.418503e-01 16 30888714 30888770 57 + 0.517 0.572 0.252
ENSG00000260083 E011 4.3907979 0.0044859677 7.716953e-01 8.526226e-01 16 30888771 30888958 188 + 0.747 0.712 -0.140
ENSG00000260083 E012 6.9828699 0.0034976497 6.291499e-01 7.445738e-01 16 30894296 30894516 221 + 0.852 0.914 0.239
ENSG00000260083 E013 5.3433128 0.0171423950 2.576987e-01 3.948638e-01 16 30894517 30894547 31 + 0.683 0.850 0.673
ENSG00000260083 E014 55.9657138 0.0008924722 1.673190e-02 4.434850e-02 16 30894548 30895220 673 + 1.798 1.709 -0.302