ENSG00000251141

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000503179 ENSG00000251141 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.992699 2.744447 2.186905 0.5990917 0.3134679 -0.3262904 0.09378037 0.06299200 0.1839515 0.03736101 0.04775394 1.4098857 0.05730000 0.03183333 0.09453333 0.06270000 0.3386940461 0.0006575988   FALSE
ENST00000505302 ENSG00000251141 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.992699 2.744447 2.186905 0.5990917 0.3134679 -0.3262904 0.07586681 0.00000000 0.1208844 0.00000000 0.06941773 3.7102216 0.05721667 0.00000000 0.06016667 0.06016667 0.1919741606 0.0006575988   FALSE
ENST00000505401 ENSG00000251141 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.992699 2.744447 2.186905 0.5990917 0.3134679 -0.3262904 0.09301809 0.05881765 0.1268243 0.03783914 0.07909457 0.9914741 0.05639583 0.02133333 0.05273333 0.03140000 0.7715360495 0.0006575988   FALSE
ENST00000505637 ENSG00000251141 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.992699 2.744447 2.186905 0.5990917 0.3134679 -0.3262904 1.41155081 2.45454378 1.2587229 0.57967155 0.31524838 -0.9579436 0.60240417 0.88573333 0.56156667 -0.32416667 0.0006575988 0.0006575988   FALSE
ENST00000508123 ENSG00000251141 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.992699 2.744447 2.186905 0.5990917 0.3134679 -0.3262904 0.15797990 0.08209591 0.3402640 0.08209591 0.02574634 1.9272339 0.10590833 0.02810000 0.16680000 0.13870000 0.1085739102 0.0006575988   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000251141 E001 6.1430400 0.003911723 0.52607566 0.65934979 5 44742420 44744899 2480 - 0.903 0.794 -0.421
ENSG00000251141 E002 1.0330444 0.015670450 0.77493684 0.85497994 5 44744900 44744912 13 - 0.282 0.311 0.197
ENSG00000251141 E003 1.1782171 0.016044872 0.94474184 0.96930400 5 44744913 44745008 96 - 0.346 0.311 -0.217
ENSG00000251141 E004 0.6298062 0.019329446 0.21576265 0.34531817 5 44745009 44745137 129 - 0.115 0.310 1.777
ENSG00000251141 E005 0.7480121 0.018948838 0.25913068 0.39649738 5 44745138 44745404 267 - 0.346 0.130 -1.807
ENSG00000251141 E006 0.2966881 0.029078516 0.26737706   5 44745405 44745408 4 - 0.206 0.000 -11.212
ENSG00000251141 E007 0.4783925 0.022677528 0.70734279 0.80528967 5 44745942 44745996 55 - 0.206 0.130 -0.804
ENSG00000251141 E008 0.6235652 0.020266808 0.42936134 0.57209223 5 44745997 44746038 42 - 0.282 0.130 -1.389
ENSG00000251141 E009 0.0000000       5 44746039 44746096 58 -      
ENSG00000251141 E010 0.0000000       5 44747627 44747696 70 -      
ENSG00000251141 E011 2.8871418 0.013763874 0.04832266 0.10620103 5 44775694 44776175 482 - 0.721 0.379 -1.609
ENSG00000251141 E012 0.2987644 0.031270298 0.26547963   5 44776756 44777036 281 - 0.206 0.000 -11.211
ENSG00000251141 E013 0.5848434 0.027248474 0.05936637 0.12555573 5 44777037 44777065 29 - 0.346 0.000 -11.948
ENSG00000251141 E014 0.6213751 0.025016589 0.42246210 0.56560457 5 44777066 44777101 36 - 0.282 0.130 -1.389
ENSG00000251141 E015 0.5911862 0.021768165 0.05901875 0.12495306 5 44777102 44777203 102 - 0.346 0.000 -11.952
ENSG00000251141 E016 7.1826983 0.002683832 0.01940074 0.05020231 5 44777204 44777328 125 - 0.790 1.002 0.809
ENSG00000251141 E017 1.8206095 0.072319437 0.83672431 0.89787256 5 44777909 44777992 84 - 0.496 0.434 -0.313
ENSG00000251141 E018 0.5922303 0.019055582 0.42553358 0.56848338 5 44785049 44785181 133 - 0.282 0.130 -1.391
ENSG00000251141 E019 1.3318220 0.012069993 0.69841802 0.79839010 5 44786826 44786952 127 - 0.402 0.311 -0.540
ENSG00000251141 E020 8.5446961 0.002259545 0.01909772 0.04955155 5 44808642 44808777 136 - 0.868 1.059 0.710