ENSG00000242759

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000657720 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.113978466 0.00000000 0.39879309 0.00000000 0.06023049 5.3532989 0.191720833 0.00000000 0.6041333 0.60413333 0.0005791782 0.0005791782 TRUE FALSE
ENST00000659503 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.004280817 0.03424654 0.00000000 0.01726809 0.00000000 -2.1455646 0.019183333 0.15346667 0.0000000 -0.15346667 0.1003207835 0.0005791782 TRUE TRUE
ENST00000659605 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.001481759 0.01185407 0.00000000 0.01185407 0.00000000 -1.1279022 0.016350000 0.13080000 0.0000000 -0.13080000 0.5958665491 0.0005791782   FALSE
ENST00000660310 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.019192428 0.04356109 0.03342526 0.04356109 0.01672345 -0.3026507 0.039662500 0.10483333 0.0397000 -0.06513333 0.3506213113 0.0005791782 TRUE FALSE
ENST00000661735 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.051316927 0.00000000 0.14157677 0.00000000 0.14157677 3.9219768 0.074454167 0.00000000 0.1382333 0.13823333 0.9851314926 0.0005791782   FALSE
ENST00000662455 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.013964385 0.02755949 0.00000000 0.02006139 0.00000000 -1.9091773 0.054029167 0.16593333 0.0000000 -0.16593333 0.1880753955 0.0005791782 TRUE TRUE
ENST00000662816 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.020660411 0.00000000 0.00000000 0.00000000 0.00000000 0.0000000 0.068791667 0.00000000 0.0000000 0.00000000   0.0005791782 TRUE FALSE
ENST00000665402 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.011475854 0.00776366 0.01145403 0.00776366 0.01145403 0.2723201 0.030354167 0.08566667 0.0294000 -0.05626667 0.7069175581 0.0005791782 TRUE FALSE
ENST00000666600 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.005234453 0.02855521 0.00000000 0.02855521 0.00000000 -1.9469258 0.011070833 0.06873333 0.0000000 -0.06873333 0.1654810739 0.0005791782 TRUE FALSE
ENST00000668075 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.003149697 0.02519757 0.00000000 0.02519757 0.00000000 -1.8154760 0.007579167 0.06063333 0.0000000 -0.06063333 0.2146104717 0.0005791782   FALSE
ENST00000669116 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.035066311 0.00000000 0.00000000 0.00000000 0.00000000 0.0000000 0.082545833 0.00000000 0.0000000 0.00000000   0.0005791782   FALSE
ENST00000669924 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.045216871 0.01059481 0.02792789 0.01059481 0.02792789 0.8809786 0.111625000 0.11690000 0.0393000 -0.07760000 0.8643505953 0.0005791782 TRUE FALSE
ENST00000671373 ENSG00000242759 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.4368077 0.2170715 0.7080379 0.1004641 0.1832346 1.660914 0.022199647 0.00000000 0.00000000 0.00000000 0.00000000 0.0000000 0.081266667 0.00000000 0.0000000 0.00000000   0.0005791782   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000242759 E001 0.1482932 0.048760277 1.770033e-01   3 106449775 106450097 323 - 0.000 0.171 12.908
ENSG00000242759 E002 0.0000000       3 106500717 106500813 97 -      
ENSG00000242759 E003 0.1817044 1.857675078 3.476629e-01   3 106557279 106557391 113 - 0.000 0.174 14.489
ENSG00000242759 E004 0.0000000       3 106630469 106630531 63 -      
ENSG00000242759 E005 0.0000000       3 106631817 106631873 57 -      
ENSG00000242759 E006 0.0000000       3 106809285 106811014 1730 -      
ENSG00000242759 E007 0.0000000       3 106811414 106811624 211 -      
ENSG00000242759 E008 0.0000000       3 106812770 106812861 92 -      
ENSG00000242759 E009 0.1472490 0.314358164 1.000000e+00   3 106830686 106833050 2365 - 0.086 0.000 -13.209
ENSG00000242759 E010 0.0000000       3 106836811 106837620 810 -      
ENSG00000242759 E011 0.0000000       3 106837621 106837621 1 -      
ENSG00000242759 E012 1.1081710 0.150636554 1.424811e-02 0.0387886146 3 106837622 106838326 705 - 0.086 0.539 3.495
ENSG00000242759 E013 0.3686942 0.242035905 4.708437e-01 0.6100354606 3 106838327 106838328 2 - 0.086 0.174 1.179
ENSG00000242759 E014 0.3686942 0.242035905 4.708437e-01 0.6100354606 3 106838329 106838329 1 - 0.086 0.174 1.179
ENSG00000242759 E015 0.3686942 0.242035905 4.708437e-01 0.6100354606 3 106838330 106838782 453 - 0.086 0.174 1.179
ENSG00000242759 E016 0.0000000       3 106839475 106839592 118 -      
ENSG00000242759 E017 0.0000000       3 106842893 106842893 1 -      
ENSG00000242759 E018 0.0000000       3 106842894 106842906 13 -      
ENSG00000242759 E019 0.0000000       3 106842907 106843067 161 -      
ENSG00000242759 E020 0.0000000       3 106843179 106843256 78 -      
ENSG00000242759 E021 0.0000000       3 106877303 106877857 555 -      
ENSG00000242759 E022 0.1817044 1.857675078 3.476629e-01   3 106877858 106878107 250 - 0.000 0.174 14.489
ENSG00000242759 E023 0.0000000       3 106878108 106878162 55 -      
ENSG00000242759 E024 0.0000000       3 106878163 106878255 93 -      
ENSG00000242759 E025 0.1451727 0.305645914 1.000000e+00   3 106878256 106878474 219 - 0.086 0.000 -13.209
ENSG00000242759 E026 0.1451727 0.305645914 1.000000e+00   3 106878990 106879072 83 - 0.086 0.000 -13.209
ENSG00000242759 E027 0.0000000       3 106909801 106909864 64 -      
ENSG00000242759 E028 0.0000000       3 106912865 106913024 160 -      
ENSG00000242759 E029 0.0000000       3 106913025 106913041 17 -      
ENSG00000242759 E030 0.0000000       3 106913042 106913166 125 -      
ENSG00000242759 E031 0.0000000       3 106913167 106913169 3 -      
ENSG00000242759 E032 0.1482932 0.048760277 1.770033e-01   3 106920832 106920965 134 - 0.000 0.171 14.960
ENSG00000242759 E033 0.2934659 0.031360943 4.971023e-01   3 106920966 106921060 95 - 0.086 0.172 1.152
ENSG00000242759 E034 0.1482932 0.048760277 1.770033e-01   3 106922058 106922093 36 - 0.000 0.171 14.960
ENSG00000242759 E035 0.3697384 0.035786163 5.002777e-02 0.1092230449 3 106925928 106926375 448 - 0.000 0.295 15.750
ENSG00000242759 E036 0.0000000       3 106927348 106927834 487 -      
ENSG00000242759 E037 0.7384326 0.145540281 7.687490e-02 0.1544976268 3 106927835 106927994 160 - 0.086 0.393 2.756
ENSG00000242759 E038 0.0000000       3 107007066 107007164 99 -      
ENSG00000242759 E039 0.0000000       3 107039655 107040074 420 -      
ENSG00000242759 E040 0.0000000       3 107040075 107040116 42 -      
ENSG00000242759 E041 0.2214452 0.467969172 2.037855e-01   3 107049797 107049902 106 - 0.000 0.176 14.828
ENSG00000242759 E042 0.1515154 0.704521069 1.000000e+00   3 107057670 107057932 263 - 0.086 0.000 -13.156
ENSG00000242759 E043 0.0000000       3 107108631 107109111 481 -      
ENSG00000242759 E044 0.0000000       3 107109112 107109112 1 -      
ENSG00000242759 E045 0.0000000       3 107109113 107109113 1 -      
ENSG00000242759 E046 0.0000000       3 107109114 107109114 1 -      
ENSG00000242759 E047 0.0000000       3 107109115 107109115 1 -      
ENSG00000242759 E048 0.0000000       3 107109116 107109120 5 -      
ENSG00000242759 E049 0.0000000       3 107109121 107109760 640 -      
ENSG00000242759 E050 0.0000000       3 107109761 107109789 29 -      
ENSG00000242759 E051 0.0000000       3 107109790 107109791 2 -      
ENSG00000242759 E052 0.1482932 0.048760277 1.770033e-01   3 107109792 107109804 13 - 0.000 0.171 14.960
ENSG00000242759 E053 2.0573696 0.047294244 4.328781e-01 0.5753334779 3 107109805 107110004 200 - 0.438 0.588 0.719
ENSG00000242759 E054 0.0000000       3 107110592 107110653 62 -      
ENSG00000242759 E055 0.0000000       3 107111409 107111481 73 -      
ENSG00000242759 E056 0.0000000       3 107111482 107111484 3 -      
ENSG00000242759 E057 2.3721315 0.060227707 2.307283e-02 0.0578989004 3 107111485 107112059 575 - 0.631 0.171 -2.758
ENSG00000242759 E058 3.5367353 0.005771505 3.610852e-05 0.0002103551 3 107112060 107112146 87 - 0.795 0.000 -16.495
ENSG00000242759 E059 0.0000000       3 107112147 107112166 20 -      
ENSG00000242759 E060 0.0000000       3 107114753 107114843 91 -      
ENSG00000242759 E061 0.0000000       3 107120974 107121308 335 -      
ENSG00000242759 E062 0.1472490 0.314358164 1.000000e+00   3 107129193 107129317 125 - 0.086 0.000 -13.209
ENSG00000242759 E063 0.0000000       3 107129408 107129887 480 -      
ENSG00000242759 E064 5.2358018 0.003615506 6.886564e-01 0.7907381238 3 107129888 107129989 102 - 0.810 0.767 -0.170
ENSG00000242759 E065 2.8752996 0.005894348 1.000000e+00 1.0000000000 3 107129990 107129992 3 - 0.584 0.592 0.037
ENSG00000242759 E066 0.0000000       3 107129993 107132074 2082 -      
ENSG00000242759 E067 0.0000000       3 107132418 107132815 398 -      
ENSG00000242759 E068 0.1482932 0.048760277 1.770033e-01   3 107135626 107135712 87 - 0.000 0.171 14.960
ENSG00000242759 E069 0.0000000       3 107139444 107139637 194 -      
ENSG00000242759 E070 0.0000000       3 107171267 107171331 65 -      
ENSG00000242759 E071 0.0000000       3 107189543 107189664 122 -      
ENSG00000242759 E072 0.0000000       3 107202914 107202981 68 -      
ENSG00000242759 E073 0.0000000       3 107202982 107203010 29 -      
ENSG00000242759 E074 0.0000000       3 107209462 107209646 185 -      
ENSG00000242759 E075 0.0000000       3 107209647 107209762 116 -      
ENSG00000242759 E076 0.0000000       3 107220727 107220895 169 -      
ENSG00000242759 E077 0.4448795 0.027025143 1.541751e-02 0.0414380237 3 107237696 107238459 764 - 0.000 0.389 16.190
ENSG00000242759 E078 0.0000000       3 107240439 107240442 4 -      
ENSG00000242759 E079 5.6639330 0.003847892 2.525849e-01 0.3889571564 3 107240443 107241087 645 - 0.865 0.729 -0.536