ENSG00000241472

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000466893 ENSG00000241472 HEK293_OSMI2_2hA HEK293_TMG_2hB PTPRG-AS1 lncRNA lncRNA 13.55019 15.81466 19.62397 0.5895101 0.8564221 0.3111781 1.0327280 0.8082034 2.233627 0.07500841 0.04250422 1.4553015 0.07042917 0.05133333 0.11446667 0.06313333 4.868562e-04 8.29677e-09   FALSE
ENST00000664758 ENSG00000241472 HEK293_OSMI2_2hA HEK293_TMG_2hB PTPRG-AS1 lncRNA lncRNA 13.55019 15.81466 19.62397 0.5895101 0.8564221 0.3111781 0.6371045 0.1737941 1.194503 0.17379411 0.61200827 2.7122755 0.04827083 0.01116667 0.06350000 0.05233333 5.499574e-01 8.29677e-09 FALSE FALSE
MSTRG.23186.28 ENSG00000241472 HEK293_OSMI2_2hA HEK293_TMG_2hB PTPRG-AS1 lncRNA   13.55019 15.81466 19.62397 0.5895101 0.8564221 0.3111781 0.3454957 0.0000000 1.277482 0.00000000 0.68669547 7.0084090 0.02507083 0.00000000 0.06826667 0.06826667 2.173401e-01 8.29677e-09   FALSE
MSTRG.23186.33 ENSG00000241472 HEK293_OSMI2_2hA HEK293_TMG_2hB PTPRG-AS1 lncRNA   13.55019 15.81466 19.62397 0.5895101 0.8564221 0.3111781 6.5177297 9.8891429 7.266875 0.33015326 0.62489491 -0.4439847 0.48615417 0.62570000 0.36983333 -0.25586667 8.296770e-09 8.29677e-09   FALSE
MSTRG.23186.6 ENSG00000241472 HEK293_OSMI2_2hA HEK293_TMG_2hB PTPRG-AS1 lncRNA   13.55019 15.81466 19.62397 0.5895101 0.8564221 0.3111781 1.3549355 0.7335888 2.247797 0.73358877 1.12413713 1.6023388 0.09809583 0.04330000 0.11003333 0.06673333 5.346354e-01 8.29677e-09   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000241472 E001 0.0000000       3 62167970 62168104 135 -      
ENSG00000241472 E002 2.3228206 0.0065883959 2.200547e-01 3.504755e-01 3 62217295 62217342 48 - 0.418 0.617 0.952
ENSG00000241472 E003 1.6585867 0.0084273112 3.606905e-01 5.050424e-01 3 62217777 62217841 65 - 0.500 0.337 -0.879
ENSG00000241472 E004 8.3969921 0.0315855799 5.029325e-01 6.389340e-01 3 62221249 62222517 1269 - 1.020 0.923 -0.359
ENSG00000241472 E005 3.3130194 0.0049144309 5.009224e-01 6.371405e-01 3 62222518 62222672 155 - 0.680 0.573 -0.462
ENSG00000241472 E006 1.2555363 0.0108647759 3.605221e-01 5.048402e-01 3 62250772 62250832 61 - 0.418 0.251 -1.047
ENSG00000241472 E007 0.7500885 0.1103221544 3.660033e-01 5.103314e-01 3 62260865 62260866 2 - 0.319 0.143 -1.475
ENSG00000241472 E008 0.7500885 0.1103221544 3.660033e-01 5.103314e-01 3 62260867 62260872 6 - 0.319 0.143 -1.475
ENSG00000241472 E009 5.5482046 0.0361896588 8.102348e-01 8.795574e-01 3 62260873 62261005 133 - 0.806 0.856 0.192
ENSG00000241472 E010 9.1567611 0.0019322773 7.166633e-02 1.461203e-01 3 62261006 62261095 90 - 0.919 1.106 0.688
ENSG00000241472 E011 9.7564957 0.0021107055 6.485918e-01 7.600663e-01 3 62261096 62261630 535 - 1.019 1.064 0.161
ENSG00000241472 E012 4.7348449 0.0037170834 6.639103e-01 7.718628e-01 3 62261631 62261822 192 - 0.788 0.725 -0.252
ENSG00000241472 E013 2.4118949 0.0067138219 9.618282e-01 9.799279e-01 3 62261823 62261824 2 - 0.535 0.525 -0.048
ENSG00000241472 E014 2.4118949 0.0067138219 9.618282e-01 9.799279e-01 3 62261825 62261826 2 - 0.535 0.525 -0.048
ENSG00000241472 E015 2.8600984 0.0161725492 5.436938e-01 6.742590e-01 3 62261827 62261844 18 - 0.628 0.525 -0.464
ENSG00000241472 E016 2.3420669 0.0261357933 1.095846e-01 2.049628e-01 3 62261845 62261845 1 - 0.628 0.338 -1.463
ENSG00000241472 E017 2.3420669 0.0261357933 1.095846e-01 2.049628e-01 3 62261846 62261850 5 - 0.628 0.338 -1.463
ENSG00000241472 E018 2.3420669 0.0261357933 1.095846e-01 2.049628e-01 3 62261851 62261852 2 - 0.628 0.338 -1.463
ENSG00000241472 E019 2.3420669 0.0261357933 1.095846e-01 2.049628e-01 3 62261853 62261859 7 - 0.628 0.338 -1.463
ENSG00000241472 E020 47.8486655 0.0005531362 1.306783e-01 2.350966e-01 3 62261860 62262619 760 - 1.723 1.645 -0.267
ENSG00000241472 E021 78.2593199 0.0004337621 1.544229e-04 7.667398e-04 3 62262620 62263874 1255 - 1.959 1.807 -0.511
ENSG00000241472 E022 17.1216684 0.0055542261 8.007523e-01 8.730038e-01 3 62263875 62263928 54 - 1.268 1.242 -0.092
ENSG00000241472 E023 21.9231521 0.0009104964 7.673213e-02 1.542598e-01 3 62263929 62264041 113 - 1.299 1.423 0.430
ENSG00000241472 E024 10.4999499 0.0016968545 9.589533e-01 9.782777e-01 3 62264042 62264045 4 - 1.062 1.064 0.007
ENSG00000241472 E025 19.7184263 0.0009727251 7.049299e-01 8.033733e-01 3 62264046 62264142 97 - 1.305 1.330 0.088
ENSG00000241472 E026 23.6793348 0.0007689400 5.015486e-10 7.847446e-09 3 62276427 62276774 348 - 1.551 1.064 -1.708
ENSG00000241472 E027 17.1229662 0.0339542701 2.668073e-04 1.244481e-03 3 62276775 62277004 230 - 1.411 0.946 -1.662
ENSG00000241472 E028 0.8010032 0.1957676820 9.981510e-01 1.000000e+00 3 62278680 62278726 47 - 0.257 0.252 -0.038
ENSG00000241472 E029 0.8062886 0.0251760125 3.392464e-01 4.831541e-01 3 62290531 62290858 328 - 0.318 0.144 -1.459
ENSG00000241472 E030 4.4254619 0.0050134295 2.507441e-02 6.202860e-02 3 62290859 62292613 1755 - 0.858 0.525 -1.402
ENSG00000241472 E031 21.5362141 0.0009363651 2.222366e-02 5.613981e-02 3 62292614 62292633 20 - 1.426 1.252 -0.607
ENSG00000241472 E032 34.7292101 0.0006391734 6.462826e-03 1.982646e-02 3 62292634 62292717 84 - 1.624 1.460 -0.561
ENSG00000241472 E033 0.2214452 0.0414014961 3.359111e-01   3 62294273 62294699 427 - 0.000 0.144 8.800
ENSG00000241472 E034 42.0236619 0.0005795706 2.073462e-02 5.302599e-02 3 62294700 62294778 79 - 1.691 1.564 -0.431
ENSG00000241472 E035 2.6131686 0.0060851327 3.432348e-01 4.872926e-01 3 62313894 62313970 77 - 0.627 0.471 -0.726
ENSG00000241472 E036 21.9901606 0.0012895951 1.105122e-09 1.625481e-08 3 62315822 62315884 63 - 1.092 1.546 1.588
ENSG00000241472 E037 85.2012499 0.0003720233 1.002999e-03 3.968742e-03 3 62317106 62317192 87 - 1.877 1.992 0.388
ENSG00000241472 E038 7.7007127 0.0029091887 4.786714e-06 3.423674e-05 3 62317193 62317230 38 - 0.599 1.145 2.124
ENSG00000241472 E039 81.9948493 0.0003875610 8.174018e-06 5.540207e-05 3 62317808 62317900 93 - 1.836 1.997 0.543
ENSG00000241472 E040 18.6527800 0.0014627173 1.386270e-02 3.791539e-02 3 62317901 62317903 3 - 1.200 1.389 0.662
ENSG00000241472 E041 0.0000000       3 62318597 62318651 55 -      
ENSG00000241472 E042 5.5314788 0.0049038022 3.560884e-01 5.004738e-01 3 62318652 62318790 139 - 0.768 0.884 0.453
ENSG00000241472 E043 3.3485058 0.0048929714 8.347810e-01 8.965711e-01 3 62318791 62318865 75 - 0.627 0.656 0.122
ENSG00000241472 E044 38.7044195 0.0005857522 1.675364e-03 6.204044e-03 3 62318866 62318960 95 - 1.513 1.682 0.574
ENSG00000241472 E045 0.0000000       3 62369192 62369305 114 -      
ENSG00000241472 E046 0.0000000       3 62369306 62369406 101 -