ENSG00000241316

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000464420 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.05555506 0.034399043 0.21914824 0.0343990425 0.009167159 2.3676807 0.12692917 0.17913333 0.24030000 0.06116667 9.914443e-01 6.694517e-05   FALSE
ENST00000496640 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.02380408 0.014866433 0.02104966 0.0148664327 0.021049664 0.3203781 0.08525000 0.12530000 0.02233333 -0.10296667 6.524158e-01 6.694517e-05 FALSE FALSE
ENST00000656446 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.03979708 0.000000000 0.21015932 0.0000000000 0.123865396 4.4604760 0.06267500 0.00000000 0.24296667 0.24296667 6.290620e-01 6.694517e-05 FALSE FALSE
ENST00000659205 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.03992266 0.024786260 0.05236848 0.0247862600 0.052368478 0.8422995 0.10637917 0.15810000 0.06376667 -0.09433333 7.604878e-01 6.694517e-05 FALSE FALSE
ENST00000659899 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.19188623 0.008830588 0.35774115 0.0088305884 0.180657974 4.2875406 0.33018333 0.04596667 0.37360000 0.32763333 6.086717e-01 6.694517e-05 FALSE FALSE
ENST00000665078 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.02512272 0.000000000 0.00000000 0.0000000000 0.000000000 0.0000000 0.08324167 0.00000000 0.00000000 0.00000000   6.694517e-05   FALSE
ENST00000671174 ENSG00000241316 HEK293_OSMI2_2hA HEK293_TMG_2hB SUCLG2-DT lncRNA lncRNA 0.4495446 0.1558186 0.913195 0.02119307 0.04687729 2.477029 0.02952328 0.062674763 0.00000000 0.0008920672 0.000000000 -2.8614545 0.10789583 0.41940000 0.00000000 -0.41940000 6.694517e-05 6.694517e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000241316 E001 0.0000000       3 67654669 67654676 8 +      
ENSG00000241316 E002 0.4460135 0.031685439 1.000000000 1.000000000 3 67654677 67654711 35 + 0.142 0.000 -10.590
ENSG00000241316 E003 0.5911862 0.019018501 1.000000000 1.000000000 3 67654712 67654731 20 + 0.180 0.000 -12.559
ENSG00000241316 E004 0.8909948 0.014074143 0.733042300 0.824365812 3 67654732 67654737 6 + 0.215 0.261 0.360
ENSG00000241316 E005 0.8909948 0.014074143 0.733042300 0.824365812 3 67654738 67654741 4 + 0.215 0.261 0.360
ENSG00000241316 E006 1.0382438 0.012198908 0.884178056 0.929962692 3 67654742 67654751 10 + 0.248 0.261 0.097
ENSG00000241316 E007 1.0382438 0.012198908 0.884178056 0.929962692 3 67654752 67654757 6 + 0.248 0.261 0.097
ENSG00000241316 E008 1.1854928 0.013066934 1.000000000 1.000000000 3 67654758 67654759 2 + 0.278 0.261 -0.125
ENSG00000241316 E009 4.0522727 0.064526128 0.077248388 0.155077147 3 67654760 67654966 207 + 0.552 0.825 1.148
ENSG00000241316 E010 3.6117602 0.005117639 0.493303401 0.630323733 3 67654967 67655046 80 + 0.552 0.633 0.361
ENSG00000241316 E011 3.5010428 0.004668761 0.178118846 0.298781475 3 67655047 67655102 56 + 0.520 0.709 0.835
ENSG00000241316 E012 0.4502799 0.064817626 1.000000000 1.000000000 3 67668247 67668277 31 + 0.142 0.000 -12.280
ENSG00000241316 E013 2.7271081 0.006020509 0.554678154 0.683620960 3 67669816 67669909 94 + 0.466 0.541 0.361
ENSG00000241316 E014 0.2966881 0.029607388 1.000000000   3 67670829 67670881 53 + 0.099 0.000 -11.907
ENSG00000241316 E015 1.7788691 0.008196461 0.709927693 0.807183199 3 67670882 67670959 78 + 0.382 0.261 -0.777
ENSG00000241316 E016 1.3338878 0.010864776 0.303066727 0.444974674 3 67670960 67671004 45 + 0.334 0.000 -13.211
ENSG00000241316 E017 0.0000000       3 67693549 67693682 134 +      
ENSG00000241316 E018 3.0784257 0.015350728 0.683541677 0.786722424 3 67746771 67746957 187 + 0.503 0.541 0.181
ENSG00000241316 E019 5.5368686 0.003505174 0.001905737 0.006933135 3 67746958 67748468 1511 + 0.624 1.003 1.498
ENSG00000241316 E020 1.6264232 0.010091000 0.209827903 0.338348966 3 67749853 67749970 118 + 0.382 0.000 -13.357
ENSG00000241316 E021 3.8207380 0.038720629 0.025148486 0.062186642 3 67750414 67750660 247 + 0.637 0.000 -13.930
ENSG00000241316 E022 23.7294801 0.001114734 0.004179735 0.013648854 3 67750661 67753596 2936 + 1.301 0.966 -1.204
ENSG00000241316 E023 0.1472490 0.049499401 0.720370880   3 67768330 67768433 104 + 0.052 0.000 -11.155
ENSG00000241316 E024 0.1472490 0.049499401 0.720370880   3 67809900 67810115 216 + 0.052 0.000 -11.155
ENSG00000241316 E025 0.4502799 0.064817626 1.000000000 1.000000000 3 67815893 67819215 3323 + 0.142 0.000 -12.280
ENSG00000241316 E026 0.1451727 0.049834040 0.720420072   3 67840022 67840839 818 + 0.052 0.000 -11.155
ENSG00000241316 E027 0.1817044 0.078149773 0.042435362   3 67844233 67844352 120 + 0.000 0.261 13.714
ENSG00000241316 E028 0.0000000       3 67889010 67889109 100 +      
ENSG00000241316 E029 0.0000000       3 67947141 67947713 573 +