ENSG00000237505

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000425750 ENSG00000237505 HEK293_OSMI2_2hA HEK293_TMG_2hB PKN2-AS1 lncRNA lncRNA 0.4518293 0.2303437 1.119013 0.07960735 0.2193313 2.231891 0.26280694 0.08325651 0.71784885 0.061946321 0.19792294 2.964363 0.43411250 0.2506333 0.61413333 0.3635000000 0.2618190228 0.0007464609   FALSE
ENST00000642677 ENSG00000237505 HEK293_OSMI2_2hA HEK293_TMG_2hB PKN2-AS1 lncRNA lncRNA 0.4518293 0.2303437 1.119013 0.07960735 0.2193313 2.231891 0.05236061 0.08837518 0.01387359 0.022433035 0.01387359 -2.042879 0.22814583 0.4407333 0.01023333 -0.4305000000 0.0007464609 0.0007464609   FALSE
ENST00000645890 ENSG00000237505 HEK293_OSMI2_2hA HEK293_TMG_2hB PKN2-AS1 lncRNA lncRNA 0.4518293 0.2303437 1.119013 0.07960735 0.2193313 2.231891 0.07447561 0.02907294 0.21726515 0.015297327 0.01486422 2.540135 0.17630000 0.1048000 0.21793333 0.1131333333 0.7621547495 0.0007464609   FALSE
ENST00000646400 ENSG00000237505 HEK293_OSMI2_2hA HEK293_TMG_2hB PKN2-AS1 lncRNA lncRNA 0.4518293 0.2303437 1.119013 0.07960735 0.2193313 2.231891 0.01203710 0.01342383 0.05971154 0.013423827 0.04185684 1.573421 0.03438333 0.1517333 0.05440000 -0.0973333333 0.9230617980 0.0007464609   FALSE
MSTRG.1545.2 ENSG00000237505 HEK293_OSMI2_2hA HEK293_TMG_2hB PKN2-AS1 lncRNA   0.4518293 0.2303437 1.119013 0.07960735 0.2193313 2.231891 0.02895051 0.01621525 0.05229774 0.009519776 0.01992910 1.248774 0.06900000 0.0521000 0.05306667 0.0009666667 0.7927291187 0.0007464609   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000237505 E001 0.0000000       1 87620803 87622207 1405 -      
ENSG00000237505 E002 0.0000000       1 87624713 87624794 82 -      
ENSG00000237505 E003 0.0000000       1 87627464 87627534 71 -      
ENSG00000237505 E004 0.0000000       1 87630415 87630497 83 -      
ENSG00000237505 E005 0.0000000       1 87637897 87638056 160 -      
ENSG00000237505 E006 0.0000000       1 87686230 87688728 2499 -      
ENSG00000237505 E007 0.0000000       1 87802864 87803005 142 -      
ENSG00000237505 E008 0.0000000       1 87899454 87899455 2 -      
ENSG00000237505 E009 0.0000000       1 87899456 87900241 786 -      
ENSG00000237505 E010 0.0000000       1 87903830 87903867 38 -      
ENSG00000237505 E011 0.0000000       1 87903868 87903898 31 -      
ENSG00000237505 E012 0.0000000       1 87903899 87904077 179 -      
ENSG00000237505 E013 0.0000000       1 87905440 87905545 106 -      
ENSG00000237505 E014 0.0000000       1 87905546 87906035 490 -      
ENSG00000237505 E015 0.0000000       1 87906060 87906163 104 -      
ENSG00000237505 E016 0.0000000       1 87906320 87906409 90 -      
ENSG00000237505 E017 0.0000000       1 87909097 87909199 103 -      
ENSG00000237505 E018 0.1482932 0.055818220 0.07234986   1 87965303 87965406 104 - 0.000 0.235 12.071
ENSG00000237505 E019 0.1482932 0.055818220 0.07234986   1 87986938 87987046 109 - 0.000 0.235 14.282
ENSG00000237505 E020 0.0000000       1 87992448 87992549 102 -      
ENSG00000237505 E021 0.0000000       1 87992997 87993277 281 -      
ENSG00000237505 E022 0.0000000       1 88034851 88034899 49 -      
ENSG00000237505 E023 0.0000000       1 88160907 88163113 2207 -      
ENSG00000237505 E024 0.0000000       1 88228096 88228297 202 -      
ENSG00000237505 E025 0.0000000       1 88269152 88269344 193 -      
ENSG00000237505 E026 0.0000000       1 88270890 88270949 60 -      
ENSG00000237505 E027 0.0000000       1 88327187 88327216 30 -      
ENSG00000237505 E028 0.0000000       1 88328946 88329083 138 -      
ENSG00000237505 E029 0.1515154 0.255651250 1.00000000   1 88472177 88472899 723 - 0.060 0.000 -10.618
ENSG00000237505 E030 0.0000000       1 88474104 88474188 85 -      
ENSG00000237505 E031 6.2276124 0.087307981 0.97929257 0.99110958 1 88513130 88515053 1924 - 0.778 0.778 0.000
ENSG00000237505 E032 0.8438645 0.016222189 0.02883194 0.06966996 1 88528836 88528930 95 - 0.112 0.500 2.883
ENSG00000237505 E033 0.9096442 0.166351647 1.00000000 1.00000000 1 88528931 88529090 160 - 0.238 0.236 -0.017
ENSG00000237505 E034 0.8042123 0.258830608 0.71484850 0.81092870 1 88530123 88530249 127 - 0.200 0.239 0.328
ENSG00000237505 E035 0.1472490 0.064772649 1.00000000   1 88537513 88537753 241 - 0.059 0.000 -10.603
ENSG00000237505 E036 1.4747940 0.009744377 0.12442667 0.22628863 1 88537754 88540302 2549 - 0.392 0.000 -13.307
ENSG00000237505 E037 2.3959778 0.006659921 0.61229645 0.73124709 1 88540303 88540571 269 - 0.485 0.388 -0.510
ENSG00000237505 E038 3.4321452 0.004953275 0.57376872 0.69969336 1 88540572 88540659 88 - 0.595 0.500 -0.440
ENSG00000237505 E039 6.2822905 0.003220097 0.30373724 0.44570699 1 88556904 88557048 145 - 0.808 0.663 -0.590
ENSG00000237505 E040 5.7277378 0.004290904 0.21566500 0.34520504 1 88569987 88570195 209 - 0.777 0.590 -0.790
ENSG00000237505 E041 1.6866874 0.009815724 0.97430558 0.98797461 1 88570810 88570859 50 - 0.366 0.388 0.128
ENSG00000237505 E042 0.0000000       1 88570860 88570860 1 -      
ENSG00000237505 E043 3.2450522 0.034471268 0.21034011 0.33895564 1 88684572 88684863 292 - 0.505 0.726 0.972
ENSG00000237505 E044 0.7686361 0.032433516 0.03164401 0.07515844 1 88684864 88684945 82 - 0.112 0.499 2.878
ENSG00000237505 E045 0.0000000       1 88685164 88685204 41 -