ENSG00000236144

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000444728	ENSG00000236144	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMEM147-AS1	lncRNA	lncRNA	20.16342	26.59209	13.48661	1.725165	0.47634	-0.9789429	1.157182	2.369745	1.0758513	0.7399932	0.4219891	-1.1319806	0.05572083	0.0889	0.0814000	-0.0075000	0.920229408	0.004010295		FALSE
ENST00000588286	ENSG00000236144	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMEM147-AS1	lncRNA	lncRNA	20.16342	26.59209	13.48661	1.725165	0.47634	-0.9789429	5.591700	5.225470	4.6365580	0.8682802	0.5399546	-0.1721566	0.28180417	0.1944	0.3418000	0.1474000	0.009261972	0.004010295	FALSE	FALSE
ENST00000589137	ENSG00000236144	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMEM147-AS1	lncRNA	lncRNA	20.16342	26.59209	13.48661	1.725165	0.47634	-0.9789429	4.780006	9.884620	2.0722429	1.6449232	0.5190682	-2.2485060	0.21273750	0.3740	0.1539000	-0.2201000	0.055751380	0.004010295		FALSE
ENST00000590717	ENSG00000236144	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMEM147-AS1	lncRNA	lncRNA	20.16342	26.59209	13.48661	1.725165	0.47634	-0.9789429	5.145903	4.114111	4.2950622	0.8096131	0.3995944	0.0619509	0.27465417	0.1526	0.3172667	0.1646667	0.004010295	0.004010295		FALSE
ENST00000670097	ENSG00000236144	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMEM147-AS1	lncRNA	lncRNA	20.16342	26.59209	13.48661	1.725165	0.47634	-0.9789429	2.135346	3.300024	0.4812424	0.3651564	0.4812424	-2.7523345	0.10411250	0.1251	0.0384000	-0.0867000	0.149786496	0.004010295	TRUE	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000236144	E001	3.32570	0.0051325525	9.513291e-01	9.735445e-01	19	35540738	35540738	1	-	0.589	0.587	-0.009
ENSG00000236144	E002	79.73665	0.0052334085	4.717241e-04	2.052002e-03	19	35540739	35540859	121	-	1.708	1.899	0.646
ENSG00000236144	E003	84.34110	0.0017363576	7.040751e-06	4.846659e-05	19	35540860	35540914	55	-	1.720	1.926	0.694
ENSG00000236144	E004	60.25320	0.0008341704	1.273757e-04	6.472891e-04	19	35540915	35540916	2	-	1.585	1.777	0.651
ENSG00000236144	E005	99.53346	0.0004077899	1.867653e-05	1.166611e-04	19	35540917	35540970	54	-	1.825	1.986	0.542
ENSG00000236144	E006	164.02247	0.0019847229	3.710540e-09	4.947222e-08	19	35540971	35541137	167	-	2.002	2.215	0.713
ENSG00000236144	E007	89.61996	0.0012689598	7.844201e-06	5.338819e-05	19	35541138	35541183	46	-	1.761	1.952	0.643
ENSG00000236144	E008	71.99778	0.0035014955	6.306892e-06	4.388855e-05	19	35541184	35541202	19	-	1.627	1.869	0.819
ENSG00000236144	E009	87.11496	0.0025026180	2.703879e-05	1.625958e-04	19	35541203	35541282	80	-	1.747	1.941	0.656
ENSG00000236144	E010	70.72058	0.0123828040	2.913671e-02	7.026302e-02	19	35541283	35541314	32	-	1.700	1.843	0.485
ENSG00000236144	E011	230.01437	0.0030816973	1.653603e-02	4.391967e-02	19	35541315	35541581	267	-	2.261	2.333	0.241
ENSG00000236144	E012	88.32309	0.0073033684	2.724302e-01	4.113092e-01	19	35541582	35541584	3	-	1.866	1.915	0.164
ENSG00000236144	E013	39.14106	0.0005380240	4.381895e-01	5.800771e-01	19	35541585	35541626	42	-	1.528	1.559	0.109
ENSG00000236144	E014	52.90840	0.0004378166	6.842257e-01	7.872443e-01	19	35541627	35541750	124	-	1.703	1.667	-0.125
ENSG00000236144	E015	226.36178	0.0001788656	8.191912e-01	8.858319e-01	19	35541751	35541928	178	-	2.317	2.296	-0.072
ENSG00000236144	E016	189.08963	0.0028421749	9.003454e-01	9.404149e-01	19	35541929	35542074	146	-	2.236	2.219	-0.056
ENSG00000236144	E017	218.31765	0.0001853347	1.670927e-01	2.844210e-01	19	35542075	35542910	836	-	2.322	2.272	-0.170
ENSG00000236144	E018	212.26282	0.0001907378	3.507075e-01	4.948938e-01	19	35542911	35543097	187	-	2.304	2.264	-0.134
ENSG00000236144	E019	144.19558	0.0002689664	1.003331e-01	1.909872e-01	19	35543098	35543273	176	-	2.155	2.087	-0.226
ENSG00000236144	E020	342.83099	0.0002174344	1.319680e-06	1.067778e-05	19	35543274	35544111	838	-	2.560	2.447	-0.375
ENSG00000236144	E021	449.31576	0.0040553638	2.916661e-09	3.967492e-08	19	35544112	35545318	1207	-	2.733	2.539	-0.647
ENSG00000236144	E022	50.00047	0.0028959755	1.429265e-05	9.159084e-05	19	35545319	35545389	71	-	1.822	1.564	-0.875
ENSG00000236144	E023	50.62116	0.0172003096	1.213348e-03	4.686342e-03	19	35545390	35545563	174	-	1.835	1.568	-0.903
ENSG00000236144	E024	17.62662	0.0124242320	4.010653e-01	5.447421e-01	19	35545937	35546029	93	-	1.285	1.188	-0.343

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000236144

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3